DE602007011756D1 - Verwendung eines p38-kinasehemmers zur behandlung von psychiatrischen erkrankungen - Google Patents
Verwendung eines p38-kinasehemmers zur behandlung von psychiatrischen erkrankungenInfo
- Publication number
- DE602007011756D1 DE602007011756D1 DE602007011756T DE602007011756T DE602007011756D1 DE 602007011756 D1 DE602007011756 D1 DE 602007011756D1 DE 602007011756 T DE602007011756 T DE 602007011756T DE 602007011756 T DE602007011756 T DE 602007011756T DE 602007011756 D1 DE602007011756 D1 DE 602007011756D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- kinase
- psychiatrical
- heather
- diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0612026.5A GB0612026D0 (en) | 2006-06-16 | 2006-06-16 | New use |
PCT/EP2007/055858 WO2007144390A1 (en) | 2006-06-16 | 2007-06-13 | Use of a p38 kinase inhibitor for treating psychiatric disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602007011756D1 true DE602007011756D1 (de) | 2011-02-17 |
Family
ID=36775828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602007011756T Active DE602007011756D1 (de) | 2006-06-16 | 2007-06-13 | Verwendung eines p38-kinasehemmers zur behandlung von psychiatrischen erkrankungen |
Country Status (13)
Country | Link |
---|---|
US (1) | US7989479B2 (de) |
EP (1) | EP2029139B1 (de) |
JP (1) | JP2010528980A (de) |
KR (1) | KR20090020703A (de) |
CN (1) | CN101500567B (de) |
AT (1) | ATE494008T1 (de) |
AU (1) | AU2007259224A1 (de) |
CA (1) | CA2657390A1 (de) |
DE (1) | DE602007011756D1 (de) |
EA (1) | EA015483B1 (de) |
ES (1) | ES2358931T3 (de) |
GB (1) | GB0612026D0 (de) |
WO (1) | WO2007144390A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1864975E (pt) * | 2002-02-12 | 2010-12-27 | Glaxosmithkline Llc | Derivados de nicotinamida úteis como inibidores de p38 |
CN102633715B (zh) * | 2012-03-23 | 2014-03-26 | 无锡爱内特营养保健品科技有限公司 | 一种丝裂原蛋白激酶p38的抑制剂及其制备方法 |
US9707219B2 (en) * | 2013-07-10 | 2017-07-18 | Glaxosmithkline Intellectual Property (No.2) Limited | Losmapimod for use in treating glomerular disease |
US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
CA3128468A1 (en) | 2017-10-05 | 2019-04-11 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce dux4 and downstream gene expression for the treatment of fshd |
WO2019103926A1 (en) * | 2017-11-21 | 2019-05-31 | Saint Louis University | P38 inhibitors for the treatment of fshd |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2373883A1 (en) * | 1999-07-02 | 2001-01-11 | Stuart A. Lipton | Method of reducing neuronal injury or apoptosis |
GB0124936D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124931D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124932D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124934D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124938D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124933D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124939D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
GB0124941D0 (en) | 2001-10-17 | 2001-12-05 | Glaxo Group Ltd | Chemical compounds |
PT1864975E (pt) | 2002-02-12 | 2010-12-27 | Glaxosmithkline Llc | Derivados de nicotinamida úteis como inibidores de p38 |
GB0209891D0 (en) | 2002-04-30 | 2002-06-05 | Glaxo Group Ltd | Novel compounds |
US20050165232A1 (en) * | 2002-05-13 | 2005-07-28 | Richard Beresis | Phenyl substituted imidaopyridines and phenyl substituted benzimidazoles |
GB0217757D0 (en) | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Novel compounds |
GB0308201D0 (en) | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
GB0308186D0 (en) | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
GB0308185D0 (en) | 2003-04-09 | 2003-05-14 | Smithkline Beecham Corp | Novel compounds |
GB0318814D0 (en) | 2003-08-11 | 2003-09-10 | Smithkline Beecham Corp | Novel compounds |
GB0402138D0 (en) | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
GB0402140D0 (en) | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
US7887802B2 (en) * | 2004-07-16 | 2011-02-15 | Atsuo Sekiyama | IL-18 receptor antagonist and pharmaceutical composition containing the antagonist |
US20080051416A1 (en) | 2004-10-05 | 2008-02-28 | Smithkline Beecham Corporation | Novel Compounds |
GB0512429D0 (en) | 2005-06-17 | 2005-07-27 | Smithkline Beecham Corp | Novel compound |
EP2032142A4 (de) | 2006-06-16 | 2010-07-21 | Glaxo Group Ltd | Neuartige verbindungen |
EP2031965A4 (de) | 2006-06-16 | 2010-06-30 | Glaxo Group Ltd | Neuartige verbindungen |
US20100144755A1 (en) | 2006-06-16 | 2010-06-10 | Glaxo Group Limited | Novel Compounds |
-
2006
- 2006-06-16 GB GBGB0612026.5A patent/GB0612026D0/en not_active Ceased
-
2007
- 2007-06-13 ES ES07730142T patent/ES2358931T3/es active Active
- 2007-06-13 EA EA200900034A patent/EA015483B1/ru not_active IP Right Cessation
- 2007-06-13 US US12/305,045 patent/US7989479B2/en not_active Expired - Fee Related
- 2007-06-13 AU AU2007259224A patent/AU2007259224A1/en not_active Abandoned
- 2007-06-13 EP EP07730142A patent/EP2029139B1/de active Active
- 2007-06-13 JP JP2009514798A patent/JP2010528980A/ja active Pending
- 2007-06-13 DE DE602007011756T patent/DE602007011756D1/de active Active
- 2007-06-13 WO PCT/EP2007/055858 patent/WO2007144390A1/en active Application Filing
- 2007-06-13 AT AT07730142T patent/ATE494008T1/de not_active IP Right Cessation
- 2007-06-13 CA CA002657390A patent/CA2657390A1/en not_active Abandoned
- 2007-06-13 CN CN2007800290002A patent/CN101500567B/zh not_active Expired - Fee Related
- 2007-06-13 KR KR1020097000928A patent/KR20090020703A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2010528980A (ja) | 2010-08-26 |
AU2007259224A1 (en) | 2007-12-21 |
CN101500567A (zh) | 2009-08-05 |
KR20090020703A (ko) | 2009-02-26 |
EP2029139A1 (de) | 2009-03-04 |
US20100016377A1 (en) | 2010-01-21 |
EP2029139B1 (de) | 2011-01-05 |
WO2007144390A1 (en) | 2007-12-21 |
US7989479B2 (en) | 2011-08-02 |
ES2358931T3 (es) | 2011-05-16 |
EA015483B1 (ru) | 2011-08-30 |
EA200900034A1 (ru) | 2009-06-30 |
ATE494008T1 (de) | 2011-01-15 |
CN101500567B (zh) | 2012-05-16 |
GB0612026D0 (en) | 2006-07-26 |
CA2657390A1 (en) | 2007-12-21 |
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