DE602007011563D1 - Vorrichtung zur analyse einer fluid-probe durch mikrodialyse und verfahren zum überwachen eines parameters einer fluid-probe - Google Patents

Vorrichtung zur analyse einer fluid-probe durch mikrodialyse und verfahren zum überwachen eines parameters einer fluid-probe

Info

Publication number
DE602007011563D1
DE602007011563D1 DE602007011563T DE602007011563T DE602007011563D1 DE 602007011563 D1 DE602007011563 D1 DE 602007011563D1 DE 602007011563 T DE602007011563 T DE 602007011563T DE 602007011563 T DE602007011563 T DE 602007011563T DE 602007011563 D1 DE602007011563 D1 DE 602007011563D1
Authority
DE
Germany
Prior art keywords
fluid sample
microdialysis
parameter
monitoring
analyzing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007011563T
Other languages
English (en)
Inventor
Franz Feichtner
Lukas Schaupp
Hans Koehler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Joanneum Research Forschungs GmbH
Original Assignee
Joanneum Research Forschungs GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Joanneum Research Forschungs GmbH filed Critical Joanneum Research Forschungs GmbH
Publication of DE602007011563D1 publication Critical patent/DE602007011563D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14525—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using microdialysis
    • A61B5/14528—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using microdialysis invasively
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/686—Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1619—Sampled collection of used dialysate, i.e. obviating the need for recovery of whole dialysate quantity for post-dialysis analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/3406—Physical characteristics of the filtrate, e.g. urea
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/031—Two or more types of hollow fibres within one bundle or within one potting or tube-sheet
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/087—Single membrane modules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/08—Flow guidance means within the module or the apparatus
    • B01D2313/086—Meandering flow path over the membrane
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/02—Details relating to pores or porosity of the membranes
    • B01D2325/022—Asymmetric membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/28—Degradation or stability over time
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/48—Antimicrobial properties

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
DE602007011563T 2006-10-19 2007-10-18 Vorrichtung zur analyse einer fluid-probe durch mikrodialyse und verfahren zum überwachen eines parameters einer fluid-probe Active DE602007011563D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86210006P 2006-10-19 2006-10-19
PCT/EP2007/009056 WO2008046630A1 (en) 2006-10-19 2007-10-18 Devices for and methods of monitoring a parameter of a fluidic sample by microdialysis

Publications (1)

Publication Number Publication Date
DE602007011563D1 true DE602007011563D1 (de) 2011-02-10

Family

ID=39083233

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007011563T Active DE602007011563D1 (de) 2006-10-19 2007-10-18 Vorrichtung zur analyse einer fluid-probe durch mikrodialyse und verfahren zum überwachen eines parameters einer fluid-probe

Country Status (5)

Country Link
US (1) US8535537B2 (de)
EP (1) EP1962993B1 (de)
AT (1) ATE493194T1 (de)
DE (1) DE602007011563D1 (de)
WO (1) WO2008046630A1 (de)

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CN103083747B (zh) * 2011-10-31 2016-08-31 深圳光启高等理工研究院 一种气液交换器
US20170000937A1 (en) * 2014-01-21 2017-01-05 Nephro-Solutions Ag Dialysis Apparatus Comprising a Dialyzer
WO2015153370A2 (en) * 2014-03-29 2015-10-08 Labib Mohamed E Blood processing cartridges and systems, and methods for extracorporeal blood therapies
EP3180065A4 (de) 2014-07-24 2018-04-11 Thomas Jefferson University Implantierbares langzeitüberwachungssystem und verfahren zur verwendung
WO2016129401A1 (ja) * 2015-02-13 2016-08-18 株式会社 村田製作所 送受信モジュール
US10426884B2 (en) 2015-06-26 2019-10-01 Novaflux Inc. Cartridges and systems for outside-in flow in membrane-based therapies
WO2017053805A1 (en) 2015-09-24 2017-03-30 Labib Mohamed E Cartridges for hollow fibre membrane-based therapies
MX2018004596A (es) * 2015-10-14 2019-09-04 Ccore Tech Gmbh Cateter de membrana.
US10709827B2 (en) 2015-10-14 2020-07-14 Technische Universität Wien Membrane catheter
WO2017100028A1 (en) 2015-12-08 2017-06-15 The Regents Of The University Of Michigan Microfabrication of a microdialysis probe with nanoporous membrane
JP6715038B2 (ja) * 2016-03-09 2020-07-01 学校法人慶應義塾 血液濾過装置
US10413658B2 (en) 2017-03-31 2019-09-17 Capillary Biomedical, Inc. Helical insertion infusion device
CN108854599B (zh) * 2018-05-14 2020-10-16 陕西师范大学 一种基于交联溶菌酶的透析膜及其应用
US20230314396A1 (en) * 2020-04-20 2023-10-05 Ortiv-Q3 Research Pvt. Ltd System and method for microdialysis for in-vitro release testing of dosage forms

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EP0038866A3 (de) 1980-04-26 1982-03-17 Ghen M. G. Raj Kompakter Dialysator mit geringer Austauschfläche, Verfahren und Gerät
FR2497114A1 (fr) 1980-12-31 1982-07-02 Hospal Sodip Appareil, utilisable comme hemodialyseur, comprenant des plaques munies de nervures ayant des zones de hauteur maximale
US4777953A (en) 1987-02-25 1988-10-18 Ash Medical Systems, Inc. Capillary filtration and collection method for long-term monitoring of blood constituents
US4832034A (en) 1987-04-09 1989-05-23 Pizziconi Vincent B Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids
PL311273A1 (en) 1993-04-29 1996-02-05 Danfoss As Fluid analyser
DE19612105C2 (de) 1996-03-27 1998-11-05 Inst Diabetestechnologie Gemei Verfahren und Anordnung zur Bestimmung der Konzentration eines Metaboliten in Biogewebe
SE513034C2 (sv) 1997-06-02 2000-06-19 Gambro Lundia Ab Metod och anordning för beräkning av dialyseffektivitet
SE511932C2 (sv) 1998-03-11 1999-12-20 Jan Liska En metod och en kateter för detektering av substanser
DE19941271A1 (de) * 1999-08-31 2001-04-05 Lienhard Pagel Mikrofluidisches Membranmodul
US6284115B1 (en) 1999-09-21 2001-09-04 Agilent Technologies, Inc. In-line flow through micro-dialysis apparatus and method for high performance liquid phase separations
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AT412060B (de) 2001-07-06 2004-09-27 Schaupp Lukas Dipl Ing Dr Tech Verfahren zur messung von konzentrationen in lebenden organismen mittels mikrodialyse und und vorrichtung zur durchführung dieses verfahrens
JP4287373B2 (ja) 2002-07-12 2009-07-01 株式会社クラレ 多孔質膜
SE0203857L (sv) * 2002-12-20 2004-06-21 Gambro Lundia Ab Permselektivt membran och förfarande för tillverkning därav
JP2005224604A (ja) 2004-01-16 2005-08-25 Asahi Kasei Medical Co Ltd 血液浄化膜およびそれを用いた血液浄化器
EP2077762B8 (de) 2006-10-18 2014-09-17 Maquet Critical Care AB Mikrodialyse-katheter und verfahren zur herstellung eines mikrodialyse-katheters
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Also Published As

Publication number Publication date
US20110011786A1 (en) 2011-01-20
EP1962993A1 (de) 2008-09-03
WO2008046630A1 (en) 2008-04-24
ATE493194T1 (de) 2011-01-15
US8535537B2 (en) 2013-09-17
EP1962993B1 (de) 2010-12-29

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