DE602007009986D1 - Nanostrukturierte lipidträger mit riluzol und diese teilchen enthaltende pharmazeutische formulierungen - Google Patents

Nanostrukturierte lipidträger mit riluzol und diese teilchen enthaltende pharmazeutische formulierungen

Info

Publication number
DE602007009986D1
DE602007009986D1 DE602007009986T DE602007009986T DE602007009986D1 DE 602007009986 D1 DE602007009986 D1 DE 602007009986D1 DE 602007009986 T DE602007009986 T DE 602007009986T DE 602007009986 T DE602007009986 T DE 602007009986T DE 602007009986 D1 DE602007009986 D1 DE 602007009986D1
Authority
DE
Germany
Prior art keywords
riluzol
pharmaceutical formulations
formulations containing
lipid carrier
nanostructured lipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007009986T
Other languages
English (en)
Inventor
Maria Luisa Bondi
Gaetano Giammona
Emanuela Fabiola Craparo
Filippo Drago
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consiglio Nazionale delle Richerche CNR
Universita degli Studi di Catania
Universita degli Studi di Palermo
Original Assignee
Consiglio Nazionale delle Richerche CNR
Universita degli Studi di Catania
Universita degli Studi di Palermo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consiglio Nazionale delle Richerche CNR, Universita degli Studi di Catania, Universita degli Studi di Palermo filed Critical Consiglio Nazionale delle Richerche CNR
Publication of DE602007009986D1 publication Critical patent/DE602007009986D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE602007009986T 2006-06-30 2007-06-26 Nanostrukturierte lipidträger mit riluzol und diese teilchen enthaltende pharmazeutische formulierungen Active DE602007009986D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001274A ITMI20061274A1 (it) 2006-06-30 2006-06-30 Vettori nanoparticellari lipidici contenenti riluzolo e composizioni farmaceutiche che li contengono
PCT/EP2007/005654 WO2008000448A2 (en) 2006-06-30 2007-06-26 Nanostructured lipid carriers containing riluzole and pharmaceutical formulations containing said particles

Publications (1)

Publication Number Publication Date
DE602007009986D1 true DE602007009986D1 (de) 2010-12-02

Family

ID=38739887

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007009986T Active DE602007009986D1 (de) 2006-06-30 2007-06-26 Nanostrukturierte lipidträger mit riluzol und diese teilchen enthaltende pharmazeutische formulierungen

Country Status (9)

Country Link
US (1) US20100247619A1 (de)
EP (1) EP2037889B1 (de)
JP (1) JP2009541391A (de)
AT (1) ATE485032T1 (de)
AU (1) AU2007264060A1 (de)
CA (1) CA2656438A1 (de)
DE (1) DE602007009986D1 (de)
IT (1) ITMI20061274A1 (de)
WO (1) WO2008000448A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2228054A1 (de) 2009-03-13 2010-09-15 ITALFARMACO S.p.A. Wässrige Riluzol-Suspensionen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4131562A1 (de) * 1991-09-18 1993-03-25 Medac Klinische Spezialpraep Arzneistofftraeger aus festen lipidteilchen-feste lipidnanosphaeren (sln)
ATE287713T1 (de) * 1999-06-04 2005-02-15 Vereniging Voor Christelijk Wetenschappelijk Onderwijs Verwendung von riluzol zur behandlung multipler sklerose
WO2003083067A2 (en) * 2002-03-28 2003-10-09 Brigham And Women's Hospital, Inc. Histone deacetylase inhibitors for the treatment of multiple sclerosis, amyotrophic lateral sclerosis and alzheimer's disease
PT1477166E (pt) * 2003-04-28 2006-12-29 Biofrontera Bioscience Gmbh Utilização de riluzole combinado com substâncias auxiliares e aditivos adequados, para o tratamento de doenças caracterizadas por uma hiperproliferação de queratinócitos, especialmente de neurodermite e psoríase
SI1797109T1 (sl) * 2004-09-09 2016-07-29 Yeda Research And Development Co., Ltd. Zmesi polipeptidov, sestavki, ki jih vsebujejo, in postopki za njihovo pripravo ter njihove uporabe

Also Published As

Publication number Publication date
ITMI20061274A1 (it) 2008-01-01
US20100247619A1 (en) 2010-09-30
JP2009541391A (ja) 2009-11-26
EP2037889B1 (de) 2010-10-20
CA2656438A1 (en) 2008-01-03
ATE485032T1 (de) 2010-11-15
EP2037889A2 (de) 2009-03-25
WO2008000448A2 (en) 2008-01-03
AU2007264060A1 (en) 2008-01-03
WO2008000448A3 (en) 2008-02-28

Similar Documents

Publication Publication Date Title
CL2017000829A1 (es) Formulación farmacéutica que comprende mezcla de anticuerpo anti-alfa4beta7, un agente tamponante, y citrato; uso de dicha formulación para tratar enfermedad inflamatoria del intestino.
CY1119140T1 (el) Συνθεσεις αντικωδικευσης και μεθοδοι κατασκευης και χρησης τους
MX2009005727A (es) Nanoparticulas de entidad anfifilica.
PH12015500407B1 (en) Methods of treating hypertriglyceridemia
BRPI0918139A2 (pt) composição, alimento medicinal ou funcional, suplemento alimentar ou dietético para tratamento de distúrbios de desenvolvimento pervasivos com terapêuticos redox-ativos e uso
WO2006108405A3 (de) Nanopartikel-wirkstoff-konjugate
EA200802208A1 (ru) Применение флибансерина для лечения расстройств полового влечения в постклимактерический период
BRPI0815577A2 (pt) Peptídeo foxm1 e agente medicinal compreendendo o mesmo.
FR2902007B1 (fr) Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s) ainsi que leurs applications notamment therapeutiques
BRPI0809667A2 (pt) Composto, medicamento e composição farmacêutica que o contém e uso do composto
MA32600B1 (fr) Formulations liquides filmogenes pour la liberation d'un medicament sur les cheveux et le cuir chevelu
CO6311006A2 (es) Composicion farmaceutica que comprende un agente que activa las celulas t regulatorias cd4+cd25+ efectiva a dosis altas
EA202091999A3 (ru) Применение ингибиторов dpp iv
IL206296A (en) History of aminopyrazole, and their medicinal products and their use in the preparation of drugs for the prevention and treatment of diseases
IL206080A0 (en) Pharmaceutical composition for use in the treatment and/or the prevention of osteoarticular diseases
RS52867B (en) GLATIRAMER ACETATOM AND RAZAGILIN COMBINED THERAPY FOR MULTIPLE SCLEROSIS
UY30215A1 (es) Derivados de cromanol sustituidos, procedimientos para su preparacion, composiciones farmacéuticas que los contienen y aplicaciones
MX2009011316A (es) Derivados del acido lipoico.
MX2009006327A (es) Compuestos heterociclicos y metodos de uso de los mismos.
IL222432A (en) Mixtures of Declofenac and low-dose beta-cyclodextrin drugs
FR2937972B1 (fr) Derives d'oxoazetidine, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique
BRPI0717369A2 (pt) Composto, medicamento, composição farmacêutica que o contém e uso do composto.
CL2009001841A1 (es) Uso de una composición de liberación sostenida de 4-aminopiridina para preparar un medicamento útil para tratar esclerosis multiple en un sujeto.
MA32635B1 (fr) Produit medicamenteux et traitement associe
WO2012097264A3 (en) Pharmaceutical compositions for topical delivery of photosensitizers and uses thereof