DE602007007204D1 - Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln - Google Patents

Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln

Info

Publication number
DE602007007204D1
DE602007007204D1 DE602007007204T DE602007007204T DE602007007204D1 DE 602007007204 D1 DE602007007204 D1 DE 602007007204D1 DE 602007007204 T DE602007007204 T DE 602007007204T DE 602007007204 T DE602007007204 T DE 602007007204T DE 602007007204 D1 DE602007007204 D1 DE 602007007204D1
Authority
DE
Germany
Prior art keywords
compound
racemating
fluorocco
dkr
substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007007204T
Other languages
English (en)
Inventor
Jason Micklefield
Anthony John Ball
Stuart Corr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ineos Fluor Holdings Ltd
Original Assignee
Ineos Fluor Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ineos Fluor Holdings Ltd filed Critical Ineos Fluor Holdings Ltd
Publication of DE602007007204D1 publication Critical patent/DE602007007204D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
DE602007007204T 2006-04-21 2007-04-19 Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln Active DE602007007204D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0607911.5A GB0607911D0 (en) 2006-04-21 2006-04-21 Process
PCT/GB2007/001426 WO2007129018A1 (en) 2006-04-21 2007-04-19 Process for dynamic kinetic resolution (dkr) of racemic compounds in (hydro) fluorocarbon solvents

Publications (1)

Publication Number Publication Date
DE602007007204D1 true DE602007007204D1 (de) 2010-07-29

Family

ID=36581012

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007007204T Active DE602007007204D1 (de) 2006-04-21 2007-04-19 Verfahren für die dynamische kinetische racematspaltung (dkr) racemischer verbindungen in fluorkohlen(wasser)stofflösungsmitteln

Country Status (10)

Country Link
US (1) US20090280558A1 (de)
EP (1) EP2010666B1 (de)
JP (1) JP2009533067A (de)
AT (1) ATE471386T1 (de)
AU (1) AU2007246952B2 (de)
CA (1) CA2644268C (de)
DE (1) DE602007007204D1 (de)
ES (1) ES2360245T3 (de)
GB (1) GB0607911D0 (de)
WO (1) WO2007129018A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100081849A1 (en) * 2006-08-25 2010-04-01 The University Of Sydney Reaction system
FR2986804A1 (fr) * 2012-02-09 2013-08-16 Servier Lab Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique ou de ses esters, et application a la synthese de l'ivabradine et de ses sels
CN104230667B (zh) * 2014-09-12 2016-04-06 王际宽 R-3,5-双三氟甲基苯乙醇的制备
CN104388516A (zh) * 2014-10-08 2015-03-04 王同俊 (r)-(+)-3-氯-1-苯丙醇的制备
JP2019532959A (ja) * 2016-10-06 2019-11-14 ヤンセン ファーマシューティカ エヌ．ベー． Ｂｔｋ阻害剤を調製するための方法および中間体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0725707B2 (ja) * 1989-04-14 1995-03-22 昭和電工株式会社 １，１，１，２―テトラフルオロエタンの精製法
DE4422045A1 (de) * 1994-06-26 1996-01-04 Hoechst Schering Agrevo Gmbh Verfahren zur enzymatischen Spaltung von 2-Amino-4-methylphosphinobutansäureamid-Derivaten
US6201151B1 (en) * 1998-12-17 2001-03-13 National Science Council Of Republic Of China Processes for preparing optically active (S)-α-aryl propionic acid or ester therof
CN1390192A (zh) * 1999-10-18 2003-01-08 三星精密化学株式会社 手性酯的制备方法
AUPR732601A0 (en) * 2001-08-28 2001-09-20 Polychip Pharmaceuticals Pty Ltd Methods for the synthesis of amines such as ephedrine and inter mediates
KR100644165B1 (ko) * 2002-03-14 2006-11-10 학교법인 포항공과대학교 아미노시클로펜타디에닐 루테늄 촉매를 이용한 키랄화합물 분할 방법
GB0306267D0 (en) * 2003-03-19 2003-04-23 Ineos Fluor Ltd Process

Also Published As

Publication number Publication date
US20090280558A1 (en) 2009-11-12
AU2007246952B2 (en) 2010-10-28
JP2009533067A (ja) 2009-09-17
CA2644268A1 (en) 2007-11-15
EP2010666A1 (de) 2009-01-07
EP2010666B1 (de) 2010-06-16
ATE471386T1 (de) 2010-07-15
ES2360245T3 (es) 2011-06-02
GB0607911D0 (en) 2006-05-31
CA2644268C (en) 2012-01-17
AU2007246952A1 (en) 2007-11-15
WO2007129018A1 (en) 2007-11-15

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