DE602007004212D1 - Hydrogele von polysaccharidmischungen für das gewebe-engineering und als wirkstoffträger - Google Patents

Hydrogele von polysaccharidmischungen für das gewebe-engineering und als wirkstoffträger

Info

Publication number
DE602007004212D1
DE602007004212D1 DE602007004212T DE602007004212T DE602007004212D1 DE 602007004212 D1 DE602007004212 D1 DE 602007004212D1 DE 602007004212 T DE602007004212 T DE 602007004212T DE 602007004212 T DE602007004212 T DE 602007004212T DE 602007004212 D1 DE602007004212 D1 DE 602007004212D1
Authority
DE
Germany
Prior art keywords
hydrogele
tissue engineering
medium carrier
polysaccharide mixtures
mixtures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007004212T
Other languages
English (en)
Inventor
Sergio Paoletti
Ivan Donati
Eleonora Marsich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universita degli Studi di Trieste
Original Assignee
Universita degli Studi di Trieste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universita degli Studi di Trieste filed Critical Universita degli Studi di Trieste
Publication of DE602007004212D1 publication Critical patent/DE602007004212D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Colloid Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE602007004212T 2006-05-22 2007-05-21 Hydrogele von polysaccharidmischungen für das gewebe-engineering und als wirkstoffträger Active DE602007004212D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000203A ITPD20060203A1 (it) 2006-05-22 2006-05-22 Idrogeli di miscele di polisaccaridi per l'ingegneria tissutale e la veicolazione di composti attivi
PCT/EP2007/054857 WO2007135114A1 (en) 2006-05-22 2007-05-21 Hydrogels of polysaccharide mixtures for tissue engineering and as carriers of active compounds

Publications (1)

Publication Number Publication Date
DE602007004212D1 true DE602007004212D1 (de) 2010-02-25

Family

ID=38481293

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007004212T Active DE602007004212D1 (de) 2006-05-22 2007-05-21 Hydrogele von polysaccharidmischungen für das gewebe-engineering und als wirkstoffträger

Country Status (10)

Country Link
US (1) US20090202640A1 (de)
EP (1) EP2029629B1 (de)
JP (1) JP5357015B2 (de)
CN (1) CN101454348A (de)
AT (1) ATE454405T1 (de)
BR (1) BRPI0711380A2 (de)
CA (1) CA2652967C (de)
DE (1) DE602007004212D1 (de)
IT (1) ITPD20060203A1 (de)
WO (1) WO2007135114A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563066B2 (en) 2007-12-17 2013-10-22 New World Pharmaceuticals, Llc Sustained release of nutrients in vivo
DE102008016998A1 (de) * 2008-04-03 2009-10-08 GÖPFERICH, Achim, Prof. Dr. Langsam lösliche quervernetzte Matrices zur Verabreichung von Proteinarzneistoffen
IT1391669B1 (it) * 2008-07-23 2012-01-17 Universita' Degli Studi Di Trieste Materiali nanocompositi formati da una matrice polisaccaridica e nanoparticelle metalliche, loro preparazione ed uso
IT1391668B1 (it) * 2008-07-23 2012-01-17 Universita' Degli Studi Di Trieste Materiali nanocompositi basati su nanoparticelle metalliche stabilizzate con polisaccaridi a struttura ramificata.
EP2547328B1 (de) * 2010-02-11 2017-06-07 Ecole Polytechnique Federale de Lausanne (EPFL) Ccr7-liganden-verabreichung und co-verabreichung in einer immuntherapie
US20130064861A1 (en) * 2010-02-17 2013-03-14 Zvi Schwartz Compositions and methods for modifying in vivo calcification of hydrogels
EP2361640A1 (de) * 2010-02-25 2011-08-31 Université de Liège Zellkultivierung in Chitosanalginathydrogelkügelchen
WO2011130528A1 (en) * 2010-04-15 2011-10-20 Fresenius Medical Care Holdings, Inc. Anticoagulant-free dialysis systems and methods
GB201020193D0 (en) * 2010-11-29 2011-01-12 Biotec Pharmacon Asa Glucan compositions
EP2776068A4 (de) 2011-11-13 2015-05-20 Suneris Inc In-situ vernetzbare polymerzusammensetzung und verfahren dafür
CN102911278B (zh) * 2012-10-18 2014-05-14 成都连接流体分离科技有限公司 一种用于卡拉胶生产的膜浓缩工艺
JP5721240B2 (ja) * 2013-05-15 2015-05-20 国立大学法人 鹿児島大学 サッチ分解菌内包マイクロカプセルと、これを用いた芝生地の保全方法、及び該マイクロカプセルの製造方法
CN103768643B (zh) * 2014-02-17 2016-04-20 周继胡 一种银离子海藻酸盐缓释抗菌凝胶及其制备方法
FR3029422B1 (fr) 2014-12-05 2017-01-13 Synolyne Pharma Microbille d'hydrogel
JP7493961B2 (ja) 2015-06-22 2024-06-03 クレシロン， インコーポレイテッド 高度に有用な止血用接着性ポリマー足場
IT201600130342A1 (it) 2016-12-22 2018-06-22 Biopolife S R L Addotti solubili di acido borico o suoi derivati e precursori con derivati oligosaccaridici del chitosano
IT201700060530A1 (it) * 2017-06-01 2018-12-01 Jointherapeutics S R L Derivati polisaccaridici idrosolubili, loro procedimento di preparazione e loro usi
IT201700111939A1 (it) * 2017-10-05 2019-04-05 Jointherapeutics S R L Composizione farmaceutica per l’uso nel trattamento di stati infiammatori
CN108948381B (zh) * 2018-07-24 2020-10-30 阿里生物新材料（常州）有限公司 一种用于去除水中银离子的壳聚糖基水凝胶及其制备方法
JP7018685B2 (ja) * 2019-03-12 2022-02-14 国立研究開発法人理化学研究所 ハイドロゲル・マイクロカプセルの製造方法、カプセルを製造するためのキット、およびその利用
EP3733755A1 (de) 2019-04-30 2020-11-04 Universita Degli Studi di Trieste Homogene hydrogele aus chitosan-oligosaccharid-derivaten und deren anwendungen
IT201900010740A1 (it) * 2019-07-02 2021-01-02 Medacta Int Sa Biocompatible compositions comprising a biocompatible thickening polymer and a chitosan derivative
WO2022240264A1 (ko) * 2021-05-14 2022-11-17 (주)유레 폴리머 조성물 및 이의 제조방법
WO2024118457A1 (en) * 2022-11-30 2024-06-06 Corning Incorporated Hydrogel material having enhanced transport properties for living organisms encapsulation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0708662A1 (de) * 1993-04-30 1996-05-01 Massachusetts Institute Of Technology Injizierbare polysaccarid-zell-zusammensetzungen
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5620706A (en) * 1995-04-10 1997-04-15 Universite De Sherbrooke Polyionic insoluble hydrogels comprising xanthan and chitosan
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
CA2212300A1 (en) * 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
US6277792B1 (en) * 1998-12-28 2001-08-21 Venture Innovations, Inc. Viscosified aqueous fluids and viscosifier therefor
KR100880622B1 (ko) * 2000-06-29 2009-01-30 바이오신텍 캐나다 인코포레이티드 연골 및 다른 조직의 복구 및 재생용 조성물 및 방법
CA2323382C (en) * 2000-10-17 2004-04-13 Pharma Mag Inc. Wound dressing
US6756363B1 (en) * 2000-11-17 2004-06-29 Wound Healing Of Oklahoma, Inc. Solutions and films of glycated chitosan
JP3616344B2 (ja) * 2001-03-29 2005-02-02 紳一郎 西村 軟骨細胞培養方法および軟骨組織再生基材
JP4607522B2 (ja) * 2004-08-31 2011-01-05 焼津水産化学工業株式会社 高分子複合体の製造方法及び該製造方法によって得られる高分子複合体、並びに該高分子複合体を用いた動物細胞の培養方法
MX2007004261A (es) * 2004-10-12 2007-06-18 Fmc Biopolymer As Sistemas de alginato auto-gelificantes y usos de los mismos.

Also Published As

Publication number Publication date
WO2007135114A1 (en) 2007-11-29
US20090202640A1 (en) 2009-08-13
CA2652967C (en) 2014-09-02
BRPI0711380A2 (pt) 2017-06-13
JP2009537268A (ja) 2009-10-29
EP2029629B1 (de) 2010-01-06
EP2029629A1 (de) 2009-03-04
ATE454405T1 (de) 2010-01-15
CN101454348A (zh) 2009-06-10
JP5357015B2 (ja) 2013-12-04
ITPD20060203A1 (it) 2007-11-23
CA2652967A1 (en) 2007-11-29

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