DE602006021791D1 - Vorrichtung zur behandlung von epilepsie und rhythmusstörungen - Google Patents

Vorrichtung zur behandlung von epilepsie und rhythmusstörungen

Info

Publication number
DE602006021791D1
DE602006021791D1 DE602006021791T DE602006021791T DE602006021791D1 DE 602006021791 D1 DE602006021791 D1 DE 602006021791D1 DE 602006021791 T DE602006021791 T DE 602006021791T DE 602006021791 T DE602006021791 T DE 602006021791T DE 602006021791 D1 DE602006021791 D1 DE 602006021791D1
Authority
DE
Germany
Prior art keywords
therapy
proximate
electrical signal
pulse generator
electrode positioned
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006021791T
Other languages
English (en)
Inventor
Imad Libbus
Andrew P Kramer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiac Pacemakers Inc
Original Assignee
Cardiac Pacemakers Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiac Pacemakers Inc filed Critical Cardiac Pacemakers Inc
Publication of DE602006021791D1 publication Critical patent/DE602006021791D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36064—Epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
    • A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3956—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
    • A61N1/3962—Implantable devices for applying electric shocks to the heart, e.g. for cardioversion in combination with another heart therapy
    • A61N1/39622—Pacing therapy
DE602006021791T 2005-12-20 2006-11-01 Vorrichtung zur behandlung von epilepsie und rhythmusstörungen Active DE602006021791D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/312,178 US7570999B2 (en) 2005-12-20 2005-12-20 Implantable device for treating epilepsy and cardiac rhythm disorders
PCT/US2006/042727 WO2007078410A1 (en) 2005-12-20 2006-11-01 Device for treating epilepsy and rhythm disorders

Publications (1)

Publication Number Publication Date
DE602006021791D1 true DE602006021791D1 (de) 2011-06-16

Family

ID=37872217

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006021791T Active DE602006021791D1 (de) 2005-12-20 2006-11-01 Vorrichtung zur behandlung von epilepsie und rhythmusstörungen

Country Status (6)

Country Link
US (1) US7570999B2 (de)
EP (1) EP1962953B1 (de)
JP (1) JP5249779B2 (de)
AT (1) ATE507872T1 (de)
DE (1) DE602006021791D1 (de)
WO (1) WO2007078410A1 (de)

Families Citing this family (171)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US7189204B2 (en) 2002-12-04 2007-03-13 Cardiac Pacemakers, Inc. Sleep detection using an adjustable threshold
US7887493B2 (en) * 2003-09-18 2011-02-15 Cardiac Pacemakers, Inc. Implantable device employing movement sensing for detecting sleep-related disorders
EP1670547B1 (de) 2003-08-18 2008-11-12 Cardiac Pacemakers, Inc. Patientenüberwachungssystem
US8606356B2 (en) 2003-09-18 2013-12-10 Cardiac Pacemakers, Inc. Autonomic arousal detection system and method
US8002553B2 (en) 2003-08-18 2011-08-23 Cardiac Pacemakers, Inc. Sleep quality data collection and evaluation
US7572226B2 (en) 2003-10-28 2009-08-11 Cardiac Pacemakers, Inc. System and method for monitoring autonomic balance and physical activity
US7657312B2 (en) 2003-11-03 2010-02-02 Cardiac Pacemakers, Inc. Multi-site ventricular pacing therapy with parasympathetic stimulation
US7783353B2 (en) 2003-12-24 2010-08-24 Cardiac Pacemakers, Inc. Automatic neural stimulation modulation based on activity and circadian rhythm
US20050149133A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Sensing with compensation for neural stimulator
US7460906B2 (en) 2003-12-24 2008-12-02 Cardiac Pacemakers, Inc. Baroreflex stimulation to treat acute myocardial infarction
US8200331B2 (en) 2004-11-04 2012-06-12 Cardiac Pacemakers, Inc. System and method for filtering neural stimulation
US20050149132A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation based on cardiac activity
US7869881B2 (en) 2003-12-24 2011-01-11 Cardiac Pacemakers, Inc. Baroreflex stimulator with integrated pressure sensor
US7668594B2 (en) 2005-08-19 2010-02-23 Cardiac Pacemakers, Inc. Method and apparatus for delivering chronic and post-ischemia cardiac therapies
US8024050B2 (en) 2003-12-24 2011-09-20 Cardiac Pacemakers, Inc. Lead for stimulating the baroreceptors in the pulmonary artery
US7509166B2 (en) 2003-12-24 2009-03-24 Cardiac Pacemakers, Inc. Automatic baroreflex modulation responsive to adverse event
US7486991B2 (en) 2003-12-24 2009-02-03 Cardiac Pacemakers, Inc. Baroreflex modulation to gradually decrease blood pressure
US20080015659A1 (en) * 2003-12-24 2008-01-17 Yi Zhang Neurostimulation systems and methods for cardiac conditions
US9020595B2 (en) * 2003-12-24 2015-04-28 Cardiac Pacemakers, Inc. Baroreflex activation therapy with conditional shut off
US8126559B2 (en) 2004-11-30 2012-02-28 Cardiac Pacemakers, Inc. Neural stimulation with avoidance of inappropriate stimulation
US7706884B2 (en) 2003-12-24 2010-04-27 Cardiac Pacemakers, Inc. Baroreflex stimulation synchronized to circadian rhythm
US8126560B2 (en) 2003-12-24 2012-02-28 Cardiac Pacemakers, Inc. Stimulation lead for stimulating the baroreceptors in the pulmonary artery
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
US7260431B2 (en) * 2004-05-20 2007-08-21 Cardiac Pacemakers, Inc. Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device
US7747323B2 (en) 2004-06-08 2010-06-29 Cardiac Pacemakers, Inc. Adaptive baroreflex stimulation therapy for disordered breathing
US7596413B2 (en) * 2004-06-08 2009-09-29 Cardiac Pacemakers, Inc. Coordinated therapy for disordered breathing including baroreflex modulation
US8175705B2 (en) 2004-10-12 2012-05-08 Cardiac Pacemakers, Inc. System and method for sustained baroreflex stimulation
EP1833559B1 (de) 2004-12-27 2010-11-24 The Feinstein Institute for Medical Research Behandlung von entzündlichen erkrankungen durch elektrische stimulation des vagus-nervs
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US7840266B2 (en) * 2005-03-11 2010-11-23 Cardiac Pacemakers, Inc. Integrated lead for applying cardiac resynchronization therapy and neural stimulation therapy
US7587238B2 (en) 2005-03-11 2009-09-08 Cardiac Pacemakers, Inc. Combined neural stimulation and cardiac resynchronization therapy
US7660628B2 (en) 2005-03-23 2010-02-09 Cardiac Pacemakers, Inc. System to provide myocardial and neural stimulation
US8406876B2 (en) 2005-04-05 2013-03-26 Cardiac Pacemakers, Inc. Closed loop neural stimulation synchronized to cardiac cycles
US7542800B2 (en) * 2005-04-05 2009-06-02 Cardiac Pacemakers, Inc. Method and apparatus for synchronizing neural stimulation to cardiac cycles
US7493161B2 (en) * 2005-05-10 2009-02-17 Cardiac Pacemakers, Inc. System and method to deliver therapy in presence of another therapy
US8473049B2 (en) 2005-05-25 2013-06-25 Cardiac Pacemakers, Inc. Implantable neural stimulator with mode switching
US7499748B2 (en) 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US7881782B2 (en) * 2005-04-20 2011-02-01 Cardiac Pacemakers, Inc. Neural stimulation system to prevent simultaneous energy discharges
US8862243B2 (en) 2005-07-25 2014-10-14 Rainbow Medical Ltd. Electrical stimulation of blood vessels
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
EP2083910B1 (de) * 2006-11-13 2019-08-14 Washington University of St. Louis Herz-pacing mit inferiorer nodaler verlängerung
EP2170456A4 (de) * 2007-07-11 2016-09-21 Mayo Foundation Vorhersage von krampfanfällen, mikroanfalls-vorläuferereignissen und relevante therapeutische verfahren und vorrichtungen
WO2009029614A1 (en) * 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
US8934971B1 (en) * 2007-11-14 2015-01-13 Pacesetter, Inc. Implantable cardiac stimulation device and method that stabilizes ventricular rate during episodes of atrial fibrillation
EP2254660A1 (de) 2008-01-29 2010-12-01 Cardiac Pacemakers, Inc. Konfigurierbare intermittierende schrittmachertherapie
US8538535B2 (en) 2010-08-05 2013-09-17 Rainbow Medical Ltd. Enhancing perfusion by contraction
US9005106B2 (en) 2008-01-31 2015-04-14 Enopace Biomedical Ltd Intra-aortic electrical counterpulsation
US8140155B2 (en) * 2008-03-11 2012-03-20 Cardiac Pacemakers, Inc. Intermittent pacing therapy delivery statistics
US8483826B2 (en) * 2008-03-17 2013-07-09 Cardiac Pacemakers, Inc. Deactivation of intermittent pacing therapy
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
US9211409B2 (en) 2008-03-31 2015-12-15 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of T-cell activity
US8417344B2 (en) * 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
US8548593B2 (en) * 2008-11-10 2013-10-01 Cardiac Pacemakers, Inc. Distal end converter for a medical device lead
CN102215909B (zh) 2008-11-18 2014-09-10 赛博恩特医疗器械公司 优化用于消炎刺激的电极放置的装置和方法
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US8172759B2 (en) * 2009-04-24 2012-05-08 Cyberonics, Inc. Methods and systems for detecting epileptic events using nonlinear analysis parameters
US8612002B2 (en) 2009-12-23 2013-12-17 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8954167B2 (en) 2009-05-26 2015-02-10 Cardiac Pacemakers, Inc. Helically formed coil for a neural cuff electrode
US8958873B2 (en) 2009-05-28 2015-02-17 Cardiac Pacemakers, Inc. Method and apparatus for safe and efficient delivery of cardiac stress augmentation pacing
EP2440284B1 (de) 2009-06-09 2018-09-12 Setpoint Medical Corporation Nervenmanschette mit tasche für einen bleifreien stimulator
US8812104B2 (en) 2009-09-23 2014-08-19 Cardiac Pacemakers, Inc. Method and apparatus for automated control of pacing post-conditioning
JP5816408B2 (ja) * 2009-11-13 2015-11-18 オリンパス株式会社 神経刺激装置
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
WO2014169145A1 (en) 2013-04-10 2014-10-16 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
EP2509683B1 (de) 2009-12-08 2017-08-23 Cardiac Pacemakers, Inc. Erkennung einer gleichzeitigen therapie bei implantierbaren medizinischen vorrichtungen
CN102858405B (zh) 2010-02-12 2015-08-19 布里格姆女子医院有限公司 心脏再同步治疗控制参数自动调节的系统和方法
WO2011140022A2 (en) 2010-05-07 2011-11-10 Cardiac Pacemakers, Inc. Output circuit for both electrostimulation and neuromodulation
JP5577469B2 (ja) 2010-09-15 2014-08-20 カーディアック ペースメイカーズ， インコーポレイテッド 神経刺激リードのリード構成の自動選択
US9155891B2 (en) 2010-09-20 2015-10-13 Neuropace, Inc. Current management system for a stimulation output stage of an implantable neurostimulation system
WO2012106297A2 (en) * 2011-02-01 2012-08-09 Brigham And Women's Hospital, Inc. System and method for cardiac resychronization therapy control parameter generation using ventricular activation simulation and surface ecg registration
US8972228B2 (en) 2011-05-03 2015-03-03 Medtronic, Inc. Assessing intra-cardiac activation patterns
WO2012154865A2 (en) 2011-05-09 2012-11-15 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
EP2726142B1 (de) 2011-06-28 2017-05-10 Cardiac Pacemakers, Inc. Zugentlastung für die elektrode einer implantierbaren medizinischen vorrichtung
JP2014521400A (ja) 2011-07-07 2014-08-28 カーディアック ペースメイカーズ， インコーポレイテッド 植え込み型医療装置リード用の絶縁および安定機構
CN103796714B (zh) 2011-07-14 2016-03-09 布里格姆女子医院有限公司 用于自动调整心脏再同步治疗控制参数的系统与方法
US9526637B2 (en) 2011-09-09 2016-12-27 Enopace Biomedical Ltd. Wireless endovascular stent-based electrodes
EP3536375A1 (de) 2011-10-04 2019-09-11 Smartstent, Pty Ltd. Messung oder stimulierung von gewebeaktivität
US8918190B2 (en) 2011-12-07 2014-12-23 Cyberonics, Inc. Implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction
US10188856B1 (en) 2011-12-07 2019-01-29 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US8600505B2 (en) 2011-12-07 2013-12-03 Cyberonics, Inc. Implantable device for facilitating control of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US8630709B2 (en) 2011-12-07 2014-01-14 Cyberonics, Inc. Computer-implemented system and method for selecting therapy profiles of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction
US8918191B2 (en) 2011-12-07 2014-12-23 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
US8577458B1 (en) 2011-12-07 2013-11-05 Cyberonics, Inc. Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with leadless heart rate monitoring
US8571654B2 (en) 2012-01-17 2013-10-29 Cyberonics, Inc. Vagus nerve neurostimulator with multiple patient-selectable modes for treating chronic cardiac dysfunction
US8700150B2 (en) 2012-01-17 2014-04-15 Cyberonics, Inc. Implantable neurostimulator for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration
WO2013142053A1 (en) 2012-03-21 2013-09-26 Cardiac Pacemakers, Inc. Systems and methods for stimulation of vagus nerve
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US8688212B2 (en) 2012-07-20 2014-04-01 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing bradycardia through vagus nerve stimulation
US9114250B2 (en) 2012-10-02 2015-08-25 Cardiac Pacemakers, Inc. Pinch to open cuff electrode
EP2903685B1 (de) 2012-10-02 2019-08-07 Cardiac Pacemakers, Inc. Manschettenelektrode mit knifföffnung
US9452290B2 (en) 2012-11-09 2016-09-27 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing tachyarrhythmia through vagus nerve stimulation
US9643008B2 (en) 2012-11-09 2017-05-09 Cyberonics, Inc. Implantable neurostimulator-implemented method for enhancing post-exercise recovery through vagus nerve stimulation
US8923964B2 (en) 2012-11-09 2014-12-30 Cyberonics, Inc. Implantable neurostimulator-implemented method for enhancing heart failure patient awakening through vagus nerve stimulation
CN104884124B (zh) 2012-12-28 2016-11-16 心脏起搏器股份公司 刺激封套与植入工具
JP6069523B2 (ja) 2013-02-13 2017-02-01 カーディアック ペースメイカーズ， インコーポレイテッド 一体型つる状体を備えたカフ電極
EP2968936A1 (de) * 2013-03-11 2016-01-20 Ohio State Innovation Foundation Systeme und verfahren zur behandlung autonomer instabilität und damit assoziierter medizinischer leiden
US9643011B2 (en) 2013-03-14 2017-05-09 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing tachyarrhythmic risk during sleep through vagus nerve stimulation
US9278219B2 (en) 2013-03-15 2016-03-08 Medtronic, Inc. Closed loop optimization of control parameters during cardiac pacing
US20140276551A1 (en) * 2013-03-15 2014-09-18 Flint Hills Scientific, L.L.C. Epileptic seizure therapies comprising partial reduction or cooling of blood flow to brain regions
US9931048B2 (en) 2013-04-30 2018-04-03 Medtronic, Inc. Systems, methods, and interfaces for identifying effective electrodes
US10064567B2 (en) 2013-04-30 2018-09-04 Medtronic, Inc. Systems, methods, and interfaces for identifying optimal electrical vectors
US10251555B2 (en) 2013-06-12 2019-04-09 Medtronic, Inc. Implantable electrode location selection
US9877789B2 (en) 2013-06-12 2018-01-30 Medtronic, Inc. Implantable electrode location selection
US9474457B2 (en) 2013-06-12 2016-10-25 Medtronic, Inc. Metrics of electrical dyssynchrony and electrical activation patterns from surface ECG electrodes
US9278220B2 (en) 2013-07-23 2016-03-08 Medtronic, Inc. Identification of healthy versus unhealthy substrate for pacing from a multipolar lead
US9282907B2 (en) 2013-07-23 2016-03-15 Medtronic, Inc. Identification of healthy versus unhealthy substrate for pacing from a multipolar lead
US9265954B2 (en) 2013-07-26 2016-02-23 Medtronic, Inc. Method and system for improved estimation of time of left ventricular pacing with respect to intrinsic right ventricular activation in cardiac resynchronization therapy
US9265955B2 (en) 2013-07-26 2016-02-23 Medtronic, Inc. Method and system for improved estimation of time of left ventricular pacing with respect to intrinsic right ventricular activation in cardiac resynchronization therapy
US9999773B2 (en) 2013-10-30 2018-06-19 Cyberonics, Inc. Implantable neurostimulator-implemented method utilizing multi-modal stimulation parameters
CN105899166B (zh) 2013-11-06 2018-07-06 伊诺佩斯生医有限公司 无线型血管内基于支架的电极
US9320446B2 (en) 2013-12-09 2016-04-26 Medtronic, Inc. Bioelectric sensor device and methods
US9986928B2 (en) 2013-12-09 2018-06-05 Medtronic, Inc. Noninvasive cardiac therapy evaluation
US9511228B2 (en) 2014-01-14 2016-12-06 Cyberonics, Inc. Implantable neurostimulator-implemented method for managing hypertension through renal denervation and vagus nerve stimulation
US9776009B2 (en) 2014-03-20 2017-10-03 Medtronic, Inc. Non-invasive detection of phrenic nerve stimulation
US9415224B2 (en) 2014-04-25 2016-08-16 Cyberonics, Inc. Neurostimulation and recording of physiological response for the treatment of chronic cardiac dysfunction
US9713719B2 (en) 2014-04-17 2017-07-25 Cyberonics, Inc. Fine resolution identification of a neural fulcrum for the treatment of chronic cardiac dysfunction
US9950169B2 (en) 2014-04-25 2018-04-24 Cyberonics, Inc. Dynamic stimulation adjustment for identification of a neural fulcrum
US9409024B2 (en) 2014-03-25 2016-08-09 Cyberonics, Inc. Neurostimulation in a neural fulcrum zone for the treatment of chronic cardiac dysfunction
US9272143B2 (en) 2014-05-07 2016-03-01 Cyberonics, Inc. Responsive neurostimulation for the treatment of chronic cardiac dysfunction
US9591982B2 (en) 2014-07-31 2017-03-14 Medtronic, Inc. Systems and methods for evaluating cardiac therapy
US9737716B2 (en) 2014-08-12 2017-08-22 Cyberonics, Inc. Vagus nerve and carotid baroreceptor stimulation system
US9770599B2 (en) 2014-08-12 2017-09-26 Cyberonics, Inc. Vagus nerve stimulation and subcutaneous defibrillation system
US9533153B2 (en) 2014-08-12 2017-01-03 Cyberonics, Inc. Neurostimulation titration process
US9586052B2 (en) 2014-08-15 2017-03-07 Medtronic, Inc. Systems and methods for evaluating cardiac therapy
US9764143B2 (en) 2014-08-15 2017-09-19 Medtronic, Inc. Systems and methods for configuration of interventricular interval
US9586050B2 (en) 2014-08-15 2017-03-07 Medtronic, Inc. Systems and methods for configuration of atrioventricular interval
WO2016028608A1 (en) 2014-08-17 2016-02-25 Nine Continents Medical, Inc. Miniature implatable neurostimulator system for sciatic nerves and their branches
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US9504832B2 (en) 2014-11-12 2016-11-29 Cyberonics, Inc. Neurostimulation titration process via adaptive parametric modification
US11253178B2 (en) 2015-01-29 2022-02-22 Medtronic, Inc. Noninvasive assessment of cardiac resynchronization therapy
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US20160310740A1 (en) * 2015-04-24 2016-10-27 Guy P. Curtis Method for stimulating heart muscle activity during the refractory period
EP3364915B1 (de) 2015-10-20 2020-10-07 The University of Melbourne Medizinische vorrichtung zur erfassung und/oder stimulation von gewebe
EP3377171B1 (de) * 2015-11-20 2022-11-09 Cardiac Pacemakers, Inc. Single-pass-koronarvenenelektrode zur mehrkammererfassung und zum schrittmachen
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US10314501B2 (en) 2016-01-20 2019-06-11 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
EP3405107B1 (de) 2016-01-20 2023-04-12 Setpoint Medical Corporation Steuerung der vagalstimulierung
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10780279B2 (en) 2016-02-26 2020-09-22 Medtronic, Inc. Methods and systems of optimizing right ventricular only pacing for patients with respect to an atrial event and left ventricular event
US11219769B2 (en) 2016-02-26 2022-01-11 Medtronic, Inc. Noninvasive methods and systems of determining the extent of tissue capture from cardiac pacing
US10532213B2 (en) 2017-03-03 2020-01-14 Medtronic, Inc. Criteria for determination of local tissue latency near pacing electrode
US10987517B2 (en) 2017-03-15 2021-04-27 Medtronic, Inc. Detection of noise signals in cardiac signals
WO2018195083A1 (en) 2017-04-18 2018-10-25 The University Of Melbourne Endovascular device for sensing and or stimulating tissue
WO2019023472A1 (en) 2017-07-28 2019-01-31 Medtronic, Inc. GENERATION OF ACTIVATION TIME
CN111050841B (zh) 2017-07-28 2023-09-26 美敦力公司 心动周期选择
WO2019036470A1 (en) 2017-08-14 2019-02-21 Setpoint Medical Corporation TESTING TEST FOR STIMULATION OF NERVE WAVE
US11419539B2 (en) 2017-12-22 2022-08-23 Regents Of The University Of Minnesota QRS onset and offset times and cycle selection using anterior and posterior electrode signals
US10492705B2 (en) 2017-12-22 2019-12-03 Regents Of The University Of Minnesota Anterior and posterior electrode signals
US10786167B2 (en) 2017-12-22 2020-09-29 Medtronic, Inc. Ectopic beat-compensated electrical heterogeneity information
US10433746B2 (en) 2017-12-22 2019-10-08 Regents Of The University Of Minnesota Systems and methods for anterior and posterior electrode signal analysis
US10799703B2 (en) 2017-12-22 2020-10-13 Medtronic, Inc. Evaluation of his bundle pacing therapy
US11529523B2 (en) 2018-01-04 2022-12-20 Cardiac Pacemakers, Inc. Handheld bridge device for providing a communication bridge between an implanted medical device and a smartphone
US10617318B2 (en) 2018-02-27 2020-04-14 Medtronic, Inc. Mapping electrical activity on a model heart
US10668290B2 (en) 2018-03-01 2020-06-02 Medtronic, Inc. Delivery of pacing therapy by a cardiac pacing device
US10918870B2 (en) 2018-03-07 2021-02-16 Medtronic, Inc. Atrial lead placement for treatment of atrial dyssynchrony
US10780281B2 (en) 2018-03-23 2020-09-22 Medtronic, Inc. Evaluation of ventricle from atrium pacing therapy
EP3773187A1 (de) 2018-03-29 2021-02-17 Medtronic, Inc. Einstellung und beurteilung einer linksventrikulären unterstützungsvorrichtung
US10940321B2 (en) 2018-06-01 2021-03-09 Medtronic, Inc. Systems, methods, and interfaces for use in cardiac evaluation
US11304641B2 (en) 2018-06-01 2022-04-19 Medtronic, Inc. Systems, methods, and interfaces for use in cardiac evaluation
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
US11697025B2 (en) 2019-03-29 2023-07-11 Medtronic, Inc. Cardiac conduction system capture
US11547858B2 (en) 2019-03-29 2023-01-10 Medtronic, Inc. Systems, methods, and devices for adaptive cardiac therapy
US11497431B2 (en) 2019-10-09 2022-11-15 Medtronic, Inc. Systems and methods for configuring cardiac therapy
US11642533B2 (en) 2019-11-04 2023-05-09 Medtronic, Inc. Systems and methods for evaluating cardiac therapy
CA3178409A1 (en) 2020-05-21 2021-11-25 Stavros ZANOS Systems and methods for vagus nerve stimulation
US11813464B2 (en) 2020-07-31 2023-11-14 Medtronic, Inc. Cardiac conduction system evaluation
US11400299B1 (en) 2021-09-14 2022-08-02 Rainbow Medical Ltd. Flexible antenna for stimulator

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4702254A (en) 1983-09-14 1987-10-27 Jacob Zabara Neurocybernetic prosthesis
CA1290813C (en) 1985-08-12 1991-10-15 Michael B. Sweeney Pacemaker for detecting and terminating a tachycardia
US4791931A (en) 1987-08-13 1988-12-20 Pacesetter Infusion, Ltd. Demand pacemaker using an artificial baroreceptor reflex
US5014698A (en) 1987-10-06 1991-05-14 Leonard Bloom Method of and system for monitoring and treating a malfunctioning heart
US5111815A (en) 1990-10-15 1992-05-12 Cardiac Pacemakers, Inc. Method and apparatus for cardioverter/pacer utilizing neurosensing
US5437285A (en) 1991-02-20 1995-08-01 Georgetown University Method and apparatus for prediction of sudden cardiac death by simultaneous assessment of autonomic function and cardiac electrical stability
US5199428A (en) 1991-03-22 1993-04-06 Medtronic, Inc. Implantable electrical nerve stimulator/pacemaker with ischemia for decreasing cardiac workload
US5318592A (en) 1991-09-12 1994-06-07 BIOTRONIK, Mess- und Therapiegerate GmbH & Co., Ingenieurburo Berlin Cardiac therapy system
US5224475A (en) 1991-11-20 1993-07-06 Medtronic, Inc. Method and apparatus for termination of ventricular tachycardia and ventricular fibrillation
US5203326A (en) 1991-12-18 1993-04-20 Telectronics Pacing Systems, Inc. Antiarrhythmia pacer using antiarrhythmia pacing and autonomic nerve stimulation therapy
US5330507A (en) * 1992-04-24 1994-07-19 Medtronic, Inc. Implantable electrical vagal stimulation for prevention or interruption of life threatening arrhythmias
WO1994000190A1 (en) 1992-06-30 1994-01-06 Medtronic, Inc. Method and apparatus for treatment of heart disorders
EP0647151B1 (de) * 1992-06-30 1997-01-15 Medtronic, Inc. Vorrichtung zur behandlung von angina pectoris
US5792187A (en) 1993-02-22 1998-08-11 Angeion Corporation Neuro-stimulation to control pain during cardioversion defibrillation
US5411531A (en) 1993-09-23 1995-05-02 Medtronic, Inc. Method and apparatus for control of A-V interval
US5522854A (en) 1994-05-19 1996-06-04 Duke University Method and apparatus for the prevention of arrhythmia by nerve stimulation
EP0688579B1 (de) 1994-06-24 2001-08-22 St. Jude Medical AB Herztherapievorrichtung
EP0688578B1 (de) * 1994-06-24 1999-11-10 Pacesetter AB Arrhythmiedetektor
US5540730A (en) 1995-06-06 1996-07-30 Cyberonics, Inc. Treatment of motility disorders by nerve stimulation
US5662689A (en) 1995-09-08 1997-09-02 Medtronic, Inc. Method and apparatus for alleviating cardioversion shock pain
US6073048A (en) 1995-11-17 2000-06-06 Medtronic, Inc. Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure
US5690681A (en) 1996-03-29 1997-11-25 Purdue Research Foundation Method and apparatus using vagal stimulation for control of ventricular rate during atrial fibrillation
US6449507B1 (en) 1996-04-30 2002-09-10 Medtronic, Inc. Method and system for nerve stimulation prior to and during a medical procedure
US6006134A (en) * 1998-04-30 1999-12-21 Medtronic, Inc. Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers
US6735471B2 (en) 1996-04-30 2004-05-11 Medtronic, Inc. Method and system for endotracheal/esophageal stimulation prior to and during a medical procedure
US7269457B2 (en) * 1996-04-30 2007-09-11 Medtronic, Inc. Method and system for vagal nerve stimulation with multi-site cardiac pacing
US6628987B1 (en) 2000-09-26 2003-09-30 Medtronic, Inc. Method and system for sensing cardiac contractions during vagal stimulation-induced cardiopalegia
WO1997045160A1 (en) * 1996-05-31 1997-12-04 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
US6479523B1 (en) 1997-08-26 2002-11-12 Emory University Pharmacologic drug combination in vagal-induced asystole
US6597954B1 (en) 1997-10-27 2003-07-22 Neuropace, Inc. System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes
US6018682A (en) 1998-04-30 2000-01-25 Medtronic, Inc. Implantable seizure warning system
WO1999065561A1 (en) 1998-06-19 1999-12-23 Cordis Webster, Inc. Method and apparatus for transvascular treatment of tachycardia and fibrillation
EP1107693A4 (de) 1998-08-24 2003-03-19 Univ Emory Verfahren und apparat zur vorhersage von anfällen basierend auf merkmalen abgeleitet von signalen die hirnaktivität andeuten
US6356788B2 (en) 1998-10-26 2002-03-12 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy for depression, migraine, neuropsychiatric disorders, partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator
US6205359B1 (en) 1998-10-26 2001-03-20 Birinder Bob Boveja Apparatus and method for adjunct (add-on) therapy of partial complex epilepsy, generalized epilepsy and involuntary movement disorders utilizing an external stimulator
US6134470A (en) 1998-11-09 2000-10-17 Medtronic, Inc. Method and apparatus for treating a tachyarrhythmic patient
US6341236B1 (en) 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6285907B1 (en) 1999-05-21 2001-09-04 Cardiac Pacemakers, Inc. System providing ventricular pacing and biventricular coordination
WO2001000273A1 (en) 1999-06-25 2001-01-04 Emory University Devices and methods for vagus nerve stimulation
ATE365574T1 (de) 1999-11-30 2007-07-15 Biotronik Gmbh & Co Kg Gerät zur regelung der herzfrequenz und der herzpumpkraft
US6438423B1 (en) 2000-01-20 2002-08-20 Electrocore Technique, Llc Method of treating complex regional pain syndromes by electrical stimulation of the sympathetic nerve chain
US6885888B2 (en) 2000-01-20 2005-04-26 The Cleveland Clinic Foundation Electrical stimulation of the sympathetic nerve chain
US6487450B1 (en) 2000-02-24 2002-11-26 Cedars-Sinai Medical Center System and method for preventing Sudden Cardiac Death by nerve sprouting from right stellate ganglion
US6466822B1 (en) 2000-04-05 2002-10-15 Neuropace, Inc. Multimodal neurostimulator and process of using it
US6371922B1 (en) 2000-04-07 2002-04-16 Cardiac Pacemakers, Inc. Method for measuring baroreflex sensitivity and therapy optimization in heart failure patients
AU2001249877A1 (en) 2000-04-13 2001-10-30 Uab Research Foundation Inter-atrial septum electrode for atrial defibrillation
US6610713B2 (en) 2000-05-23 2003-08-26 North Shore - Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US6511500B1 (en) 2000-06-06 2003-01-28 Marc Mounir Rahme Use of autonomic nervous system neurotransmitters inhibition and atrial parasympathetic fibers ablation for the treatment of atrial arrhythmias and to preserve drug effects
DE60018556T2 (de) 2000-07-11 2006-03-02 Sorin Biomedica Crm S.R.L., Saluggia Implantierbarer Herzschrittmacher mit automatischer durch Sympathiko-Vagal Abgleichung gesteuerter Betriebsartumschaltung
US6487446B1 (en) 2000-09-26 2002-11-26 Medtronic, Inc. Method and system for spinal cord stimulation prior to and during a medical procedure
US6522926B1 (en) 2000-09-27 2003-02-18 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US7499742B2 (en) * 2001-09-26 2009-03-03 Cvrx, Inc. Electrode structures and methods for their use in cardiovascular reflex control
US6985774B2 (en) 2000-09-27 2006-01-10 Cvrx, Inc. Stimulus regimens for cardiovascular reflex control
US7158832B2 (en) * 2000-09-27 2007-01-02 Cvrx, Inc. Electrode designs and methods of use for cardiovascular reflex control devices
US8086314B1 (en) * 2000-09-27 2011-12-27 Cvrx, Inc. Devices and methods for cardiovascular reflex control
US6850801B2 (en) 2001-09-26 2005-02-01 Cvrx, Inc. Mapping methods for cardiovascular reflex control devices
DE60140072D1 (de) 2000-10-26 2009-11-12 Meditronic Inc Vorrichtung zur minimierung der wirkungen eines herzinsults
JP2004512104A (ja) 2000-10-26 2004-04-22 メドトロニック・インコーポレーテッド 心臓組織を発作から保護する方法および装置
US8417334B2 (en) 2000-10-26 2013-04-09 Medtronic, Inc. Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac conditions
US7428436B2 (en) 2000-11-02 2008-09-23 Cardiac Pacemakers, Inc. Method for exclusion of ectopic events from heart rate variability metrics
US6600954B2 (en) 2001-01-25 2003-07-29 Biocontrol Medical Bcm Ltd. Method and apparatus for selective control of nerve fibers
US6788975B1 (en) 2001-01-30 2004-09-07 Advanced Bionics Corporation Fully implantable miniature neurostimulator for stimulation as a therapy for epilepsy
CA2450376A1 (en) 2001-04-20 2002-10-31 The Board Of Regents Of The University Of Oklahoma Cardiac neuromodulation and methods of using same
US6684105B2 (en) 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US6628988B2 (en) 2001-04-27 2003-09-30 Cardiac Pacemakers, Inc. Apparatus and method for reversal of myocardial remodeling with electrical stimulation
US6928320B2 (en) 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
EP1395335A1 (de) 2001-05-29 2004-03-10 Medtronic, Inc. Neuromodulation mit geschlossenem regelkreis zur verhinderung und behandlung von herzzuständen
US6810285B2 (en) 2001-06-28 2004-10-26 Neuropace, Inc. Seizure sensing and detection using an implantable device
US6748271B2 (en) 2001-07-27 2004-06-08 Cardiac Pacemakers, Inc. Method and system for treatment of neurocardiogenic syncope
US6622041B2 (en) 2001-08-21 2003-09-16 Cyberonics, Inc. Treatment of congestive heart failure and autonomic cardiovascular drive disorders
US6934583B2 (en) 2001-10-22 2005-08-23 Pacesetter, Inc. Implantable lead and method for stimulating the vagus nerve
US6973349B2 (en) 2001-12-05 2005-12-06 Cardiac Pacemakers, Inc. Method and apparatus for minimizing post-infarct ventricular remodeling
US6937896B1 (en) 2002-02-26 2005-08-30 Pacesetter, Inc. Sympathetic nerve stimulator and/or pacemaker
US7239912B2 (en) 2002-03-22 2007-07-03 Leptos Biomedical, Inc. Electric modulation of sympathetic nervous system
US7123959B2 (en) 2002-03-25 2006-10-17 Cardiac Pacemakers, Inc. Method and apparatus for preventing cardiac arrhythmias with endovascular stimulation
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US6990372B2 (en) 2002-04-11 2006-01-24 Alfred E. Mann Foundation For Scientific Research Programmable signal analysis device for detecting neurological signals in an implantable device
US7277761B2 (en) * 2002-06-12 2007-10-02 Pacesetter, Inc. Vagal stimulation for improving cardiac function in heart failure or CHF patients
US7860570B2 (en) 2002-06-20 2010-12-28 Boston Scientific Neuromodulation Corporation Implantable microstimulators and methods for unidirectional propagation of action potentials
US7292890B2 (en) 2002-06-20 2007-11-06 Advanced Bionics Corporation Vagus nerve stimulation via unidirectional propagation of action potentials
SE0202537D0 (sv) * 2002-08-28 2002-08-28 Siemens Elema Ab Nervstimuleringsapparat
US6965797B2 (en) 2002-09-13 2005-11-15 Cardiac Pacemakers, Inc. Method and apparatus for assessing and treating myocardial wall stress
US20030229380A1 (en) 2002-10-31 2003-12-11 Adams John M. Heart failure therapy device and method
US7305265B2 (en) 2002-11-25 2007-12-04 Terumo Kabushiki Kaisha Heart treatment equipment for treating heart failure
US7221979B2 (en) * 2003-04-30 2007-05-22 Medtronic, Inc. Methods and apparatus for the regulation of hormone release
US7783353B2 (en) * 2003-12-24 2010-08-24 Cardiac Pacemakers, Inc. Automatic neural stimulation modulation based on activity and circadian rhythm
US20050149132A1 (en) * 2003-12-24 2005-07-07 Imad Libbus Automatic baroreflex modulation based on cardiac activity
US8396560B2 (en) * 2004-11-18 2013-03-12 Cardiac Pacemakers, Inc. System and method for closed-loop neural stimulation
US7260431B2 (en) * 2004-05-20 2007-08-21 Cardiac Pacemakers, Inc. Combined remodeling control therapy and anti-remodeling therapy by implantable cardiac device
US8600521B2 (en) * 2005-01-27 2013-12-03 Cyberonics, Inc. Implantable medical device having multiple electrode/sensor capability and stimulation based on sensed intrinsic activity
US7769446B2 (en) * 2005-03-11 2010-08-03 Cardiac Pacemakers, Inc. Neural stimulation system for cardiac fat pads
US7493161B2 (en) * 2005-05-10 2009-02-17 Cardiac Pacemakers, Inc. System and method to deliver therapy in presence of another therapy

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