DE602006020037D1 - Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren - Google Patents

Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren

Info

Publication number
DE602006020037D1
DE602006020037D1 DE602006020037T DE602006020037T DE602006020037D1 DE 602006020037 D1 DE602006020037 D1 DE 602006020037D1 DE 602006020037 T DE602006020037 T DE 602006020037T DE 602006020037 T DE602006020037 T DE 602006020037T DE 602006020037 D1 DE602006020037 D1 DE 602006020037D1
Authority
DE
Germany
Prior art keywords
vygfvracl
hla
cell receptors
binding
specifically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006020037T
Other languages
German (de)
English (en)
Inventor
Bent Karsten Jakobsen
Yi Avidex Limit Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunocore Ltd
Original Assignee
Immunocore Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2005/002078 external-priority patent/WO2005116646A1/en
Application filed by Immunocore Ltd filed Critical Immunocore Ltd
Priority claimed from PCT/GB2006/001857 external-priority patent/WO2006125962A2/en
Publication of DE602006020037D1 publication Critical patent/DE602006020037D1/de
Anticipated expiration legal-status Critical
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DE602006020037T 2005-05-25 2006-05-19 Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren Active DE602006020037D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/GB2005/002078 WO2005116646A1 (en) 2004-05-26 2005-05-25 Method for the identification of a polypeptide which binds to a given pmhc complex
GBGB0524477.7A GB0524477D0 (en) 2005-11-30 2005-11-30 Isolated T cell receptors which specifically bind to vygfvracl-hla-24
PCT/GB2006/001857 WO2006125962A2 (en) 2005-05-25 2006-05-19 T cell receptors which specifically bind to vygfvracl-hla-a24

Publications (1)

Publication Number Publication Date
DE602006020037D1 true DE602006020037D1 (de) 2011-03-24

Family

ID=35685841

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006020037T Active DE602006020037D1 (de) 2005-05-25 2006-05-19 Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren

Country Status (8)

Country Link
US (1) US8017730B2 (https=)
EP (1) EP1885754B1 (https=)
JP (1) JP5149789B2 (https=)
CN (1) CN101389652B (https=)
AT (1) ATE497976T1 (https=)
DE (1) DE602006020037D1 (https=)
ES (1) ES2360598T3 (https=)
GB (1) GB0524477D0 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
WO2013169691A1 (en) 2012-05-07 2013-11-14 Trustees Of Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
KR102499753B1 (ko) 2012-07-27 2023-02-16 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 Ｔ 세포 수용체 조작
EP3404111A1 (en) * 2013-03-13 2018-11-21 Health Research, Inc. Compositions and methods for use of recombinant t cell receptors for direct recognition of tumor antigen
KR102415259B1 (ko) 2013-11-22 2022-06-30 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 조작된 고-친화도의 인간 t 세포 수용체
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516277D0 (en) * 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
WO2017076308A1 (zh) * 2015-11-04 2017-05-11 广州市香雪制药股份有限公司 识别ny-eso-1抗原短肽的tcr
CN107987155A (zh) * 2016-10-27 2018-05-04 中国科学院广州生物医药与健康研究院 识别sage1抗原短肽的t细胞受体
CN109251243B (zh) * 2017-07-13 2021-10-19 中国科学院广州生物医药与健康研究院 一种识别sage1抗原的t细胞受体及编码该受体的核酸
WO2019069125A1 (en) 2017-10-06 2019-04-11 Oslo Universitetssykehus Hf CHIMERIC ANTIGEN RECEPTORS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759243B2 (en) * 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
IL160359A0 (en) * 2001-08-31 2004-07-25 Avidex Ltd Soluble t cell receptor
PT1558643E (pt) * 2002-11-09 2009-08-24 Immunocore Ltd Apresentação de um receptor das células t
ATE430164T1 (de) * 2004-05-26 2009-05-15 Immunocore Ltd Hochaffine telomerase-t-zellen-rezeptoren
GB0427585D0 (en) * 2004-12-16 2005-01-19 Avidex Ltd Assay

Also Published As

Publication number Publication date
EP1885754B1 (en) 2011-02-09
US20080292602A1 (en) 2008-11-27
JP5149789B2 (ja) 2013-02-20
CN101389652A (zh) 2009-03-18
ATE497976T1 (de) 2011-02-15
US8017730B2 (en) 2011-09-13
EP1885754A2 (en) 2008-02-13
JP2009506753A (ja) 2009-02-19
GB0524477D0 (en) 2006-01-11
ES2360598T3 (es) 2011-06-07
CN101389652B (zh) 2013-05-29

Similar Documents

Publication Publication Date Title
WO2006125962A3 (en) T cell receptors which specifically bind to vygfvracl-hla-a24
DE602006020037D1 (de) Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren
BRPI0716649A2 (pt) poliuretanos antiestÁticos e eletricamente condutores
WO2008038002A3 (en) T cell therapies
GB2467666A (en) Wearable towel
MA31231B1 (fr) Anticorps anti-robo4 et utilisations de ceux-ci
NZ585131A (en) Use melanocortins to treat insulin sensitivity
BRPI0510674A (pt) variantes fc otimizadas
NO20083153L (no) Kjemiske forbindelser
WO2007104062A3 (en) Compositions and methods based on peptide binding profiling
GB0724532D0 (en) Trail variants for treating cancer
EA200702677A1 (ru) Высокоаффинные мелан-а т-клеточные рецепторы
MX2013008375A (es) Anticuerpos anti proteina accesoria del receptor de interleucina-1 y su uso para tratamiento en humanos.
BRPI0519000A2 (pt) variantes de il-7 com imunogenicidade reduzida
CY1115188T1 (el) Πολυκυκλικες ετεροαρυλ-υποκατεστημενες τριαζολες χρησιμες ως αναστολεις του axl
MX2010007716A (es) Combinacion de una proteina de fusion del anticuerpo-il-2 de anti-edb fibronectina y una molecula que se une a celulas b, progenitores de la celula b y/o sus contrapartes cancerigenas.
WO2007112193A3 (en) Camptothecin-binding moiety conjugates
EP4470556A3 (en) Markers of acute myeloid leukemia stem cells
WO2009100194A3 (en) Camptothecin-binding moiety conjugates
TW200700433A (en) Acylated glp-1 compounds
WO2009022154A3 (en) Peptide with multiple epitopes
GT200600046A (es) Terapia de combinacion
MA31918B1 (fr) Agents et épitopes de liaison à wise
CR11504A (es) Deteccion mejorada de la expresion de mage-a
MX2010006279A (es) 4-fenilpiran-3,5-dionas, 4-feniltiopiran-3,5-dionas y 2-fenil de ciclohexan-1,3,5-trionas como herbicidas.