DE602006019437D1 - Affinitätschromatografieverfahren für antithrombin iii - Google Patents

Affinitätschromatografieverfahren für antithrombin iii

Info

Publication number
DE602006019437D1
DE602006019437D1 DE602006019437T DE602006019437T DE602006019437D1 DE 602006019437 D1 DE602006019437 D1 DE 602006019437D1 DE 602006019437 T DE602006019437 T DE 602006019437T DE 602006019437 T DE602006019437 T DE 602006019437T DE 602006019437 D1 DE602006019437 D1 DE 602006019437D1
Authority
DE
Germany
Prior art keywords
atiii
protein
affinity
antithrombin iii
affinity chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006019437T
Other languages
English (en)
Inventor
Pierre Mourier
Gerald Perret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE602006019437D1 publication Critical patent/DE602006019437D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3823—Affinity chromatography of other types, e.g. avidin, streptavidin, biotin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE602006019437T 2005-07-27 2006-07-26 Affinitätschromatografieverfahren für antithrombin iii Active DE602006019437D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0507986A FR2889078B1 (fr) 2005-07-27 2005-07-27 Nouvelle methode de chromatographie d'affinite d'antithrombine iii
PCT/FR2006/001820 WO2007012754A1 (fr) 2005-07-27 2006-07-26 Methode de chromatographie d' affinite d' antithrombine iii

Publications (1)

Publication Number Publication Date
DE602006019437D1 true DE602006019437D1 (de) 2011-02-17

Family

ID=35892408

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006019437T Active DE602006019437D1 (de) 2005-07-27 2006-07-26 Affinitätschromatografieverfahren für antithrombin iii

Country Status (21)

Country Link
US (1) US8608961B2 (de)
EP (1) EP1909938B1 (de)
JP (1) JP4931923B2 (de)
KR (1) KR101261662B1 (de)
CN (1) CN101262919B (de)
AT (1) ATE494051T1 (de)
AU (1) AU2006273918B2 (de)
BR (1) BRPI0614669A2 (de)
CA (1) CA2616132A1 (de)
CY (1) CY1118533T1 (de)
DE (1) DE602006019437D1 (de)
DK (1) DK1909938T3 (de)
ES (1) ES2357220T3 (de)
FR (1) FR2889078B1 (de)
HK (1) HK1124278A1 (de)
IL (1) IL188412A (de)
PL (1) PL1909938T3 (de)
PT (1) PT1909938E (de)
RU (1) RU2411982C2 (de)
SI (1) SI1909938T1 (de)
WO (1) WO2007012754A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2889078B1 (fr) 2005-07-27 2007-11-02 Aventis Pharma Sa Nouvelle methode de chromatographie d'affinite d'antithrombine iii
AR085961A1 (es) 2011-04-11 2013-11-06 Sanofi Sa Polisacaridos que poseen dos sitios de union a la antitrombina iii, metodo para prepararlos y composiciones farmaceuticas que los contienen
CN114958963B (zh) * 2022-07-29 2023-09-05 深圳传世生物医疗有限公司 一种作用于凝血酶的抗凝药物检测试剂盒及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0043159B1 (de) * 1980-06-27 1985-09-04 Akzo N.V. Mit einer unbeweglichen organischen Phase überzogenes anorganisches poröses Trägermaterial, Anwendung für die Chromatographie und sein Herstellungsverfahren
DE3170001D1 (en) * 1980-09-30 1985-05-23 Bayer Ag Method for the production of an antithrombin-heparin complex and pharmaceutical compositions containing the complex
SU1708400A1 (ru) * 1988-06-06 1992-01-30 Таджикский государственный университет им.В.И.Ленина Способ получени сорбента дл гемосорбции
US5744457A (en) * 1995-03-31 1998-04-28 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
EP1026172A4 (de) * 1997-10-23 2003-05-07 Fujimori Kogyo Co Methode zur reinigung von thrombinsubstraten und/oder -inhibitoren oder methode zu deren eliminierung
JP2005013156A (ja) * 2003-06-27 2005-01-20 Fujimori Kogyo Co Ltd 固定化物及びその再生方法
FR2889078B1 (fr) 2005-07-27 2007-11-02 Aventis Pharma Sa Nouvelle methode de chromatographie d'affinite d'antithrombine iii

Also Published As

Publication number Publication date
FR2889078A1 (fr) 2007-02-02
KR101261662B1 (ko) 2013-05-06
EP1909938B1 (de) 2011-01-05
RU2008107317A (ru) 2009-09-10
US20080188650A1 (en) 2008-08-07
IL188412A0 (en) 2008-12-29
JP4931923B2 (ja) 2012-05-16
BRPI0614669A2 (pt) 2011-04-12
SI1909938T1 (sl) 2011-04-29
ATE494051T1 (de) 2011-01-15
KR20080031320A (ko) 2008-04-08
ES2357220T3 (es) 2011-04-20
FR2889078B1 (fr) 2007-11-02
CN101262919A (zh) 2008-09-10
US8608961B2 (en) 2013-12-17
CA2616132A1 (fr) 2007-02-01
WO2007012754A1 (fr) 2007-02-01
IL188412A (en) 2013-07-31
PT1909938E (pt) 2011-03-03
CN101262919B (zh) 2011-07-27
AU2006273918B2 (en) 2011-04-07
RU2411982C2 (ru) 2011-02-20
CY1118533T1 (el) 2017-07-12
AU2006273918A1 (en) 2007-02-01
HK1124278A1 (en) 2009-07-10
EP1909938A1 (de) 2008-04-16
DK1909938T3 (da) 2011-04-26
JP2009503483A (ja) 2009-01-29
PL1909938T3 (pl) 2011-06-30

Similar Documents

Publication Publication Date Title
ATE425989T1 (de) Proteinreinigungsverfahren
MX9707909A (es) Purificacion de anticuerpos.
EA201500952A1 (ru) Способы очистки рекомбинантного adamts13 и других белков и их композиции
WO2007109163A3 (en) Wash buffer and method of using
DE602004026343D1 (de) Verfahren zur aufreinigung von proteinen in einer durchflussfraktion aus der chromatographie mit hydrophoben wechselwirkungen
WO2007067983A3 (en) Sulfotyrosine specific antibodies and uses therefor
UA98585C2 (uk) Антитіло, яке специфічно зв'язується з нейропіліном-1 (nrp1)
SE9803838D0 (sv) A chromatography method and a column material useful in said method
SG170749A1 (en) Anti-ilt7 antibody
MX2008007716A (es) Metodo para eliminar extra corporalmente de la sangre un microbio patogeno, una celula inflamatoria o una proteina inflamatoria.
BR112012024956A2 (pt) processo para a purificação de uma proteína de fator de crescimento
CY1118533T1 (el) Μεθοδος χρωματογραφιας συναφειας αντιδρομβινης iii
BR0312521A (pt) Métodos para a separação e a purificação de fibrinogênio e de pelo menos uma outra proteìna e para a co-purificação de fibrinogênio e de fator xiii, uso de cromatografia de afinidade com ìon de metal imobilizado, fibrinogênio, kit farmacêutico, e, formulações farmacêutica e de fibrinogênio liofilizado
WO2006035060A3 (en) Purification of a bulk of a factor vii polypeptide by fractionated elution from an anion-exchange material
PL2115010T3 (pl) Zmniejszanie zawartości endotoksyny w kwasach polisialowych
GB2368641A (en) Methods and compositions fo assaying analytes
WO2005033286A3 (en) Compositions and methods for synthesizing, purifying and detecting biomolecules
DK1064066T3 (da) Adsorptionschromatografi
HK1116995A1 (en) Secretory cell-containing macrobeads comprising seakem gold agarose, and uses thereof
Surovtsev et al. Adsorption chromatography of proteins
ME01043B (me) Metode za prećišćavanje fsh-a
WO2006053972A3 (fr) Agents de silanisation a groupement saccharidique terminal et leurs utilisations, notamment pour la fonctionnalisation de supports solides
DK1509555T3 (da) Polyvinylethere
SE0203551D0 (sv) Prothrombin purification
SINOsICH et al. INTERACTIONS OF PREGNANCY ASSOCIATED PLASMA PROTEIN-A AND O2 MACROGLOBULIN ON METAL CHELATE AFFINITY CHROMATOGRAPHY