DE602006018619D1 - Zusammensetzungen zur behandlung von luminalen entzündlichen erkrankungen - Google Patents
Zusammensetzungen zur behandlung von luminalen entzündlichen erkrankungenInfo
- Publication number
- DE602006018619D1 DE602006018619D1 DE602006018619T DE602006018619T DE602006018619D1 DE 602006018619 D1 DE602006018619 D1 DE 602006018619D1 DE 602006018619 T DE602006018619 T DE 602006018619T DE 602006018619 T DE602006018619 T DE 602006018619T DE 602006018619 D1 DE602006018619 D1 DE 602006018619D1
- Authority
- DE
- Germany
- Prior art keywords
- compositions
- cees
- luminous
- treatment
- inflammatory diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/087—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being an annexin, e.g. annexin V
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Radiation-Therapy Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70137105P | 2005-07-20 | 2005-07-20 | |
PCT/US2006/027526 WO2007015774A2 (en) | 2005-07-20 | 2006-07-13 | Methods and compositions for treating luminal inflammatory disease |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006018619D1 true DE602006018619D1 (de) | 2011-01-13 |
Family
ID=37709042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006018619T Active DE602006018619D1 (de) | 2005-07-20 | 2006-07-13 | Zusammensetzungen zur behandlung von luminalen entzündlichen erkrankungen |
Country Status (6)
Country | Link |
---|---|
US (3) | US7874975B2 (de) |
EP (1) | EP1909901B8 (de) |
AT (1) | ATE489994T1 (de) |
DE (1) | DE602006018619D1 (de) |
ES (1) | ES2353532T3 (de) |
WO (1) | WO2007015774A2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7874975B2 (en) * | 2005-07-20 | 2011-01-25 | Clear Vascular, Inc. | Methods and compositions for treating luminal inflammatory disease |
US8283167B2 (en) * | 2009-02-11 | 2012-10-09 | Clear Vascular Inc. | Preparation of annexin derivatives |
JP2016522832A (ja) * | 2013-05-23 | 2016-08-04 | ニューロエスエヌ・インコーポレイテッド | 放射性核種で標識したアネキシンを使用したアルツハイマー病の診断及び治療 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4647445A (en) | 1984-03-28 | 1987-03-03 | Massachusetts Institute Of Technology | Radiolabelled lipoproteins and method for making same |
US4937067A (en) | 1984-12-13 | 1990-06-26 | Massachusetts Institute Of Technology | Method and means for detection of adrenal metabolic activity |
US4660563A (en) | 1984-12-31 | 1987-04-28 | Massachusetts Institute Of Technology | Method and means for detection of arterial lesions |
US5225181A (en) | 1985-06-07 | 1993-07-06 | The Research Foundation Of State University Of New York | Radiolabeled antiplatelet monoclonal antibody for imaging in-vivo thrombi |
US4877599A (en) | 1986-11-10 | 1989-10-31 | New England Deaconess Hospital Corporation | Detection of vascular disease with labelled antibodies |
US5726153A (en) | 1988-05-02 | 1998-03-10 | New England Deaconess Hospital Corporation | Synthetic peptides for arterial imaging |
EP0413766A4 (en) | 1988-05-02 | 1991-11-21 | New England Deaconess Hospital Corporation | Synthetic peptides for arterial imaging |
CA1340977C (en) | 1988-11-15 | 2000-04-25 | Monty Krieger | Scavenger receptor protein and antibody thereto |
US5334729A (en) | 1989-06-29 | 1994-08-02 | Associated Universities, Inc. | Stable radiometal antibody immunoconjugates |
US5216130A (en) * | 1990-05-17 | 1993-06-01 | Albany Medical College | Complex for in-vivo target localization |
US7238340B1 (en) | 1991-11-27 | 2007-07-03 | Cis Bio International | Monoamine, diamide, thiol-containing metal chelating agents |
DK0630265T3 (da) | 1992-03-13 | 2003-06-30 | Diatide Inc | Technetium-99m mærkede peptider til afbildning af inflammation |
US5292938A (en) | 1992-04-13 | 1994-03-08 | Associated Universities, Inc. | Synthesis of 4-substituted-trans-1, 2-diaminocyclohexyl polyaminocarboxylate metal chelating agents for the preparation of stable radiometal antibody immunoconjugates for therapy and spect and pet imaging |
US5429133A (en) | 1992-12-18 | 1995-07-04 | Neoprobe Corporation | Radiation responsive laparoscopic instrument |
US5428156A (en) | 1993-04-02 | 1995-06-27 | Associated Universities, Inc. | Synthesis of macrocyclic polyaminocarboxylates and their use for preparing stable radiometal antibody immunoconjugates for therapy, spect and pet imaging |
US5968477A (en) | 1994-01-24 | 1999-10-19 | Neorx Corporation | Radiolabeled annexin conjugates with hexose and a chelator |
JP3122319B2 (ja) * | 1994-05-02 | 2001-01-09 | アソシエーティド ユニバーシティーズ,インコーポレイティド | 錫−117m−含有放射性治療剤 |
US5783169A (en) | 1995-07-26 | 1998-07-21 | Brookhaven Science Associates Llc | Rigid bifunctional chelating agents |
US5811814A (en) | 1996-02-12 | 1998-09-22 | Cordis Corporation | Radiation measuring catheter apparatus and method |
WO1998048699A1 (en) | 1997-04-30 | 1998-11-05 | The Board Of Trustees Of The Leland Stanford Junior University | Method of imaging cell death in vivo |
US6500108B1 (en) | 1999-10-22 | 2002-12-31 | The Regents Of The University Of California | Radiation delivery system and method |
JP2004530654A (ja) * | 2001-02-23 | 2004-10-07 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | アテローム硬化症および脆弱性プラークを画像診断するための標識マクロファージスカベンジャー受容体拮抗薬 |
US20030103995A1 (en) * | 2001-06-04 | 2003-06-05 | Hamblin Michael R. | Detection and therapy of vulnerable plaque with photodynamic compounds |
US6549802B2 (en) | 2001-06-07 | 2003-04-15 | Varian Medical Systems, Inc. | Seed localization system and method in ultrasound by fluoroscopy and ultrasound fusion |
US20030152513A1 (en) | 2001-09-06 | 2003-08-14 | Imetrix, Inc. | Intravascular delivery of therapeutic and imaging agents to stressed and apoptotic cells using annexin V as a targeting vector |
US7874975B2 (en) * | 2005-07-20 | 2011-01-25 | Clear Vascular, Inc. | Methods and compositions for treating luminal inflammatory disease |
-
2006
- 2006-07-05 US US11/428,823 patent/US7874975B2/en not_active Expired - Fee Related
- 2006-07-13 WO PCT/US2006/027526 patent/WO2007015774A2/en active Application Filing
- 2006-07-13 EP EP06787437A patent/EP1909901B8/de not_active Not-in-force
- 2006-07-13 DE DE602006018619T patent/DE602006018619D1/de active Active
- 2006-07-13 ES ES06787437T patent/ES2353532T3/es active Active
- 2006-07-13 AT AT06787437T patent/ATE489994T1/de not_active IP Right Cessation
-
2010
- 2010-12-08 US US12/963,508 patent/US8753255B2/en active Active
-
2014
- 2014-03-28 US US14/229,082 patent/US9283290B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1909901B8 (de) | 2011-02-02 |
US20140212356A1 (en) | 2014-07-31 |
US20110077211A1 (en) | 2011-03-31 |
EP1909901A4 (de) | 2009-09-23 |
US7874975B2 (en) | 2011-01-25 |
EP1909901A2 (de) | 2008-04-16 |
US20070021641A1 (en) | 2007-01-25 |
ATE489994T1 (de) | 2010-12-15 |
ES2353532T3 (es) | 2011-03-02 |
WO2007015774A3 (en) | 2007-11-01 |
WO2007015774A2 (en) | 2007-02-08 |
US9283290B2 (en) | 2016-03-15 |
EP1909901B1 (de) | 2010-12-01 |
US8753255B2 (en) | 2014-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: CLEAR VASCULAR, INC., THE WOODLANDS, TEX., US |