DE602006018577D1 - Blutstillungstest - Google Patents

Blutstillungstest

Info

Publication number
DE602006018577D1
DE602006018577D1 DE602006018577T DE602006018577T DE602006018577D1 DE 602006018577 D1 DE602006018577 D1 DE 602006018577D1 DE 602006018577 T DE602006018577 T DE 602006018577T DE 602006018577 T DE602006018577 T DE 602006018577T DE 602006018577 D1 DE602006018577 D1 DE 602006018577D1
Authority
DE
Germany
Prior art keywords
plasmin
thrombin
specific
cleavage
measurable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006018577T
Other languages
English (en)
Inventor
Heerde Waander Laurens Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stichting Katholieke Universiteit
Original Assignee
Stichting Katholieke Universiteit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Katholieke Universiteit filed Critical Stichting Katholieke Universiteit
Publication of DE602006018577D1 publication Critical patent/DE602006018577D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/20—Coumarin derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE602006018577T 2005-01-07 2006-01-09 Blutstillungstest Active DE602006018577D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05075030 2005-01-07
PCT/EP2006/000184 WO2006072602A1 (en) 2005-01-07 2006-01-09 Hemostasis assay

Publications (1)

Publication Number Publication Date
DE602006018577D1 true DE602006018577D1 (de) 2011-01-13

Family

ID=35871110

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006018577T Active DE602006018577D1 (de) 2005-01-07 2006-01-09 Blutstillungstest

Country Status (8)

Country Link
US (1) US8809006B2 (de)
EP (1) EP1833982B1 (de)
JP (1) JP4931826B2 (de)
AT (1) ATE490337T1 (de)
CA (1) CA2592748C (de)
DE (1) DE602006018577D1 (de)
ES (1) ES2357112T3 (de)
WO (1) WO2006072602A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006035899A1 (de) * 2006-07-31 2008-02-07 Dade Behring Marburg Gmbh Polysacharid-Peptid-Konjugate zur Verwendung als Thrombinsubstrate
FR2917172B1 (fr) * 2007-06-07 2014-01-03 Inst Nat Sante Rech Med Methode de mesure de l'activite plasmine des microparticules presentes dans un echantillon de fluide biologique et utilisation
US8261327B2 (en) * 2007-07-12 2012-09-04 Wayport, Inc. Device-specific authorization at distributed locations
WO2011057143A1 (en) * 2009-11-06 2011-05-12 The Regents Of The University Of Colorado, A Body Corporate Compositions, methods and uses for simultaneous assay of thrombin and plasmin generation
EP3228714B1 (de) 2010-12-14 2019-03-27 Stichting Katholieke Universiteit Chemilumineszenzbasierter hämostasetest
EP2465941A1 (de) * 2010-12-20 2012-06-20 Siemens Healthcare Diagnostics Products GmbH Verfahren zur simultanen Bestimmung mehrerer Gerinnungsproteasen
FR2978164B1 (fr) * 2011-07-22 2013-08-30 Stago Diagnostica Utilisation d'un substrat dans une methode pour mesurer l'activite des enzymes proteolytiques
FR2978163B1 (fr) 2011-07-22 2013-08-30 Stago Diagnostica Utilisation d'un substrat dans une methode pour mesurer l'activite des enzymes proteolytiques disponibles
US10200391B2 (en) * 2015-09-23 2019-02-05 AVAST Software s.r.o. Detection of malware in derived pattern space
JP7101351B2 (ja) 2016-04-28 2022-07-15 シスメックス株式会社 血液検体の分析方法、血液検体分析用試薬及び試薬キット、並びに血液検体分析装置
EP3363912B1 (de) 2017-02-17 2020-10-28 Synapse B.V. Selbstkalibrierter assay zur bestimmung der erzeugung von proteolytischem enzym, dedizierte mittel und verwendungen davon
WO2020079155A1 (en) 2018-10-17 2020-04-23 Enzyre B.V. Novel chemiluminescent substrates for factor xa
WO2023074864A1 (ja) * 2021-10-29 2023-05-04 国立大学法人浜松医科大学 血漿中線溶抵抗性活性の評価方法
WO2024153750A1 (en) 2023-01-18 2024-07-25 Enzyre B.V. Luminescent detection of adamts13

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096807A (en) * 1985-03-06 1992-03-17 Murex Corporation Imaging immunoassay detection system with background compensation and its use
US5231006A (en) * 1986-10-16 1993-07-27 Behringwerke Aktiengesellschaft Method for the determination of plasminogen
US5110727A (en) 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
NL8902406A (nl) 1989-09-27 1991-04-16 Hendrik Coenraad Hemker Prof D Werkwijze voor het bepalen van de endogene trombinepotentiaal van plasma, en bloed alsmede een bij deze werkwijze te gebruiken kit.
US5510243A (en) * 1994-06-21 1996-04-23 Gelman Sciences, Inc. Multiple chromogen enzyme targeting (MCET) for use in bacterial contamination monitoring
DK0947585T3 (da) * 1998-03-19 2001-10-01 Instrumentation Lab Spa Forbedret in vitro-fremgangsmåde, kits og reagenser til screening for blodkoagulationsdefekter
US6899877B2 (en) * 1999-03-09 2005-05-31 Minu, L.L.C. Process for generating plasmin in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina
US6245548B1 (en) * 2000-03-09 2001-06-12 American National Red Cross Activation of pure prothrombin to thrombin with about 30% to about 40% sodium citrate
US7524826B2 (en) * 2000-04-14 2009-04-28 Mcmaster University And Hamilton Health Sciences Corporation Method of inhibiting the generation of active thrombin on the surface of a cell within an atherosclerotic plaque
US8802386B2 (en) * 2002-05-01 2014-08-12 Synapse B.V. Diagnostic test for determining the concentration of transient proteolytic activity in composite biological media
AU2003270554A1 (en) * 2002-09-09 2004-03-29 Applera Corporation Fluorescent enzyme assay methods and compositions
AU2005289774B2 (en) 2004-09-22 2012-03-08 The Regents Of The University Of Colorado Methods for a global assay of coagulation and fibrinolysis

Also Published As

Publication number Publication date
WO2006072602A1 (en) 2006-07-13
US8809006B2 (en) 2014-08-19
EP1833982A1 (de) 2007-09-19
US20080026365A1 (en) 2008-01-31
JP2008526219A (ja) 2008-07-24
ES2357112T3 (es) 2011-04-18
ATE490337T1 (de) 2010-12-15
JP4931826B2 (ja) 2012-05-16
CA2592748A1 (en) 2006-07-13
CA2592748C (en) 2014-04-22
EP1833982B1 (de) 2010-12-01

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