DE602006017199D1 - Hemmung reaktiver sauerstoffspezies und schutz von säugerzellen - Google Patents
Hemmung reaktiver sauerstoffspezies und schutz von säugerzellenInfo
- Publication number
- DE602006017199D1 DE602006017199D1 DE602006017199T DE602006017199T DE602006017199D1 DE 602006017199 D1 DE602006017199 D1 DE 602006017199D1 DE 602006017199 T DE602006017199 T DE 602006017199T DE 602006017199 T DE602006017199 T DE 602006017199T DE 602006017199 D1 DE602006017199 D1 DE 602006017199D1
- Authority
- DE
- Germany
- Prior art keywords
- oxygen species
- reactive oxygen
- ros
- protection
- mammalian cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67604305P | 2005-04-29 | 2005-04-29 | |
US71663005P | 2005-09-13 | 2005-09-13 | |
PCT/US2006/016050 WO2006118954A2 (en) | 2005-04-29 | 2006-04-27 | Inhibition of reactive oxygen species and protection of mammalian cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602006017199D1 true DE602006017199D1 (de) | 2010-11-11 |
Family
ID=37308499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602006017199T Active DE602006017199D1 (de) | 2005-04-29 | 2006-04-27 | Hemmung reaktiver sauerstoffspezies und schutz von säugerzellen |
Country Status (7)
Country | Link |
---|---|
US (2) | US7727559B2 (de) |
EP (2) | EP2359907A1 (de) |
AT (1) | ATE482748T1 (de) |
AU (1) | AU2006242541B2 (de) |
CA (1) | CA2610296C (de) |
DE (1) | DE602006017199D1 (de) |
WO (1) | WO2006118954A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110111007A1 (en) * | 2005-04-29 | 2011-05-12 | Mcginnis James F | Inhibition of retinal cell degeneration or neovascularization by cerium oxide nanoparticles |
JP2008546842A (ja) * | 2005-06-27 | 2008-12-25 | エドワード ヴィア バージニア カレッジ オブ オステオパシック メディスン | 酸化セリウムナノ粒子の抗炎症性、放射線防護性および寿命促進能 |
US10857178B2 (en) * | 2005-06-27 | 2020-12-08 | Edward Via Virginia College Of Osteopathic Medicine | Cerium oxide nanoparticles for treatment and prevention of Alzheimer's disease, Parkinson's disease, and disorders associated with free radical production and/or mitochondrial dysfunction |
US9649337B2 (en) | 2005-06-27 | 2017-05-16 | Edward Via Virginia College Of Osteopathic Medicine | Cerium oxide nanoparticles for the treatment and prevention of stroke and cardiovascular disease |
US7959949B2 (en) | 2006-04-27 | 2011-06-14 | University Of Central Florida Research Foundation, Inc. | Functionalized nanoceria composition for ophthalmic treatment |
WO2008064357A2 (en) * | 2006-11-22 | 2008-05-29 | University Of Florida Research Foundation, Inc. | Nanoparticles for protection of cells from oxidative stress |
US20080166412A1 (en) * | 2007-01-02 | 2008-07-10 | Kiminobu Sugaya | Methods and materials for stimulating proliferation of stem cell |
US9119391B1 (en) | 2007-07-16 | 2015-09-01 | University Of Central Florida Research Foundation, Inc. | Polymer coated ceria nanoparticles for selective cytoprotection |
US8916199B1 (en) | 2008-04-25 | 2014-12-23 | University of Central Florida Research Foundation, Ind. | Inhibition of angiogenesis associated with ovarian cancer by nanoparticles of cerium oxide |
EP2288258A4 (de) * | 2008-04-25 | 2012-10-31 | Univ Oklahoma | Inhibition of neovascularization by cerium oxide nanoparticles |
US9207385B2 (en) | 2008-05-06 | 2015-12-08 | Qd Vision, Inc. | Lighting systems and devices including same |
WO2009151515A1 (en) | 2008-05-06 | 2009-12-17 | Qd Vision, Inc. | Solid state lighting devices including quantum confined semiconductor nanoparticles |
US9127202B1 (en) | 2008-07-18 | 2015-09-08 | University Of Central Florida Research Foundation, Inc. | Biocompatible nano rare earth oxide upconverters for imaging and therapeutics |
US20100098768A1 (en) * | 2008-10-16 | 2010-04-22 | Clarkson University | Method of neuroprotection from oxidant injury using metal oxide nanoparticles |
US8883519B1 (en) | 2009-03-17 | 2014-11-11 | University Of Central Florida Research Foundation, Inc. | Oxidase activity of polymeric coated cerium oxide nanoparticles |
WO2010129374A2 (en) | 2009-04-28 | 2010-11-11 | Qd Vision, Inc. | Optical materials, optical components, and methods |
US9585840B1 (en) | 2009-07-10 | 2017-03-07 | University Of Central Florida Research Foundation, Inc. | Redox active cerium oxide nanoparticles and associated methods |
US8795731B1 (en) | 2009-10-12 | 2014-08-05 | University Of Central Florida Research Foundation, Inc. | Cerium oxide nanoparticle-based device for the detection of reactive oxygen species and monitoring of chronic inflammation |
US8877207B2 (en) | 2010-09-17 | 2014-11-04 | University Of Central Florida Research Foundation, Inc. | Nanoparticles of cerium oxide targeted to an amyloid-beta antigen of Alzheimer's disease and associated methods |
US11116792B1 (en) | 2010-12-22 | 2021-09-14 | Biocurity Holdings, Inc. | Cerium oxide nanoparticle formulation for use in skin radioprotection and associated methods |
US8951539B1 (en) | 2011-06-07 | 2015-02-10 | University Of Central Florida Research Foundation, Inc. | Methods of promoting angiogenesis using cerium oxide nanoparticles |
US9161950B2 (en) | 2011-09-21 | 2015-10-20 | University Of Central Florida Foundation, Inc. | Neuronal protection by cerium oxide nanoparticles |
US9415065B2 (en) | 2012-04-04 | 2016-08-16 | University Of Central Florida Research Foundation, Inc. | Methods of using cerium oxide nanoparticles to mitigate or protect against radiation injury |
US9463437B2 (en) | 2013-02-14 | 2016-10-11 | University Of Central Florida Research Foundation, Inc. | Methods for scavenging nitric oxide using cerium oxide nanoparticles |
US9669055B1 (en) | 2014-04-11 | 2017-06-06 | Marshall University Research Corporation | Methods for treating sepsis |
US11389536B2 (en) | 2015-07-17 | 2022-07-19 | BioCurity Pharmaceuticals Inc. | Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent |
CN108685847A (zh) * | 2018-06-29 | 2018-10-23 | 温州医科大学 | 一种针对氧化损伤诱导炎症的长效抗炎眼用分散制剂 |
EP4074319A1 (de) | 2021-04-15 | 2022-10-19 | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca | Ophthalmische topische zusammensetzung mit ceroxid-nanoteilchen zur behandlung von erkrankungen des hinteren augensegments |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US676043A (en) | 1899-11-22 | 1901-06-11 | John C Lincoln | Electric drill. |
US716630A (en) | 1902-03-24 | 1902-12-23 | August Eimer | Crucible. |
US6291506B1 (en) * | 1998-08-04 | 2001-09-18 | Wisconsin Alumni Research Foundation | Method of reducing retinal ganglion cell degeneration |
WO2000035415A1 (de) * | 1998-12-11 | 2000-06-22 | Cognis Deutschland Gmbh | Verwendung von nanoskaligen organischen uv-lichtschutzfiltern |
US7930285B2 (en) * | 2000-03-22 | 2011-04-19 | Comscore, Inc. | Systems for and methods of user demographic reporting usable for identifying users and collecting usage data |
FR2809637B1 (fr) * | 2000-06-05 | 2003-01-24 | Rhodia Terres Rares | Dispersion colloidale d'un compose de cerium ou d'un compose de cerium et d'au moins un autre element choisi parmi les terres rares et des metaux de transition et comprenant un acide amine |
CN1189505C (zh) * | 2000-07-05 | 2005-02-16 | 日本Arc株式会社 | 透明层压体、眼镜用塑料镜片和底涂剂组合物 |
WO2003059193A2 (en) * | 2001-12-21 | 2003-07-24 | Alcon, Inc. | Use of nanoparticles as carriers for biocides in ophthalmic compositions |
US7431758B2 (en) * | 2002-10-28 | 2008-10-07 | Nissan Chemical Industries, Ltd. | Cerium oxide particles and production method therefor |
WO2004096146A2 (en) * | 2003-04-25 | 2004-11-11 | Nolan Gerard M | Method and composition for preventing, reducing and reversing ocular ischemic neuronal damage |
-
2006
- 2006-04-27 AU AU2006242541A patent/AU2006242541B2/en not_active Ceased
- 2006-04-27 US US11/412,665 patent/US7727559B2/en active Active
- 2006-04-27 EP EP10181322A patent/EP2359907A1/de not_active Withdrawn
- 2006-04-27 AT AT06751658T patent/ATE482748T1/de not_active IP Right Cessation
- 2006-04-27 CA CA2610296A patent/CA2610296C/en not_active Expired - Fee Related
- 2006-04-27 EP EP06751658A patent/EP1879570B1/de not_active Not-in-force
- 2006-04-27 WO PCT/US2006/016050 patent/WO2006118954A2/en active Application Filing
- 2006-04-27 DE DE602006017199T patent/DE602006017199D1/de active Active
-
2007
- 2007-04-27 US US11/796,347 patent/US7347987B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20060246152A1 (en) | 2006-11-02 |
ATE482748T1 (de) | 2010-10-15 |
WO2006118954A8 (en) | 2007-08-23 |
EP2359907A1 (de) | 2011-08-24 |
WO2006118954A3 (en) | 2007-05-24 |
US7347987B2 (en) | 2008-03-25 |
EP1879570B1 (de) | 2010-09-29 |
AU2006242541B2 (en) | 2011-12-08 |
CA2610296C (en) | 2016-06-14 |
WO2006118954A2 (en) | 2006-11-09 |
EP1879570A4 (de) | 2008-10-01 |
US20070202193A1 (en) | 2007-08-30 |
CA2610296A1 (en) | 2006-11-09 |
AU2006242541A1 (en) | 2006-11-09 |
EP1879570A2 (de) | 2008-01-23 |
US7727559B2 (en) | 2010-06-01 |
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