DE602006014522D1 - Ligand für den vesikulären acetylcholintransporter - Google Patents

Ligand für den vesikulären acetylcholintransporter

Info

Publication number
DE602006014522D1
DE602006014522D1 DE602006014522T DE602006014522T DE602006014522D1 DE 602006014522 D1 DE602006014522 D1 DE 602006014522D1 DE 602006014522 T DE602006014522 T DE 602006014522T DE 602006014522 T DE602006014522 T DE 602006014522T DE 602006014522 D1 DE602006014522 D1 DE 602006014522D1
Authority
DE
Germany
Prior art keywords
ligand
acetylcholine transporter
vesicular acetylcholine
vesicular
transporter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006014522T
Other languages
English (en)
Inventor
Kiichi Ishiwata
Kazuhiro Shiba
Hideo Tsukada
Shingo Nishiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanazawa University NUC
Original Assignee
Kanazawa University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanazawa University NUC filed Critical Kanazawa University NUC
Publication of DE602006014522D1 publication Critical patent/DE602006014522D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K51/0457—Vesamicol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE602006014522T 2005-04-01 2006-03-31 Ligand für den vesikulären acetylcholintransporter Active DE602006014522D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005106824 2005-04-01
PCT/JP2006/307418 WO2006107106A1 (ja) 2005-04-01 2006-03-31 小胞アセチルコリントランスポーターに対するリガンド

Publications (1)

Publication Number Publication Date
DE602006014522D1 true DE602006014522D1 (de) 2010-07-08

Family

ID=37073638

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006014522T Active DE602006014522D1 (de) 2005-04-01 2006-03-31 Ligand für den vesikulären acetylcholintransporter

Country Status (5)

Country Link
US (1) US20090163461A1 (de)
EP (1) EP1867634B1 (de)
JP (1) JP4985977B2 (de)
DE (1) DE602006014522D1 (de)
WO (1) WO2006107106A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110043766A (ko) * 2008-09-20 2011-04-27 고쿠리츠 다이가쿠 호진 교토 다이가쿠 췌도 이미징용 분자 프로브 전구체 및 그의 사용
WO2011027584A1 (ja) * 2009-09-04 2011-03-10 国立大学法人京都大学 膵島イメージング用分子プローブ及びその使用
JP5608867B2 (ja) * 2009-09-30 2014-10-15 国立大学法人京都大学 膵島イメージング用分子プローブ及びその使用
KR101550006B1 (ko) * 2009-12-10 2015-09-03 아크레이 가부시키가이샤 췌도 이미징용 분자 프로브 및 그 사용
US9278146B2 (en) 2010-10-08 2016-03-08 Kyoto University Peptide derivative and use of the same
JP6496101B2 (ja) * 2013-04-05 2019-04-03 浜松ホトニクス株式会社 アセチルコリン小胞トランスポーターの検出に適した化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338852A (en) * 1992-06-03 1994-08-16 Regents Of The University Of Minnesota Azavesamicols
WO2001007427A1 (fr) * 1999-07-28 2001-02-01 Daiichi Radioisotope Laboratories, Ltd. Derives de vesamicol piperazine et medicaments renfermant ces derives

Also Published As

Publication number Publication date
EP1867634A4 (de) 2009-03-25
WO2006107106A1 (ja) 2006-10-12
JP4985977B2 (ja) 2012-07-25
JPWO2006107106A1 (ja) 2008-10-02
EP1867634A1 (de) 2007-12-19
US20090163461A1 (en) 2009-06-25
EP1867634B1 (de) 2010-05-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition