DE602005025647D1 - Polypeptide für die oligomerisierung von antigenen - Google Patents

Polypeptide für die oligomerisierung von antigenen

Info

Publication number
DE602005025647D1
DE602005025647D1 DE602005025647T DE602005025647T DE602005025647D1 DE 602005025647 D1 DE602005025647 D1 DE 602005025647D1 DE 602005025647 T DE602005025647 T DE 602005025647T DE 602005025647 T DE602005025647 T DE 602005025647T DE 602005025647 D1 DE602005025647 D1 DE 602005025647D1
Authority
DE
Germany
Prior art keywords
polypeptides
polypeptide
oligomerisation
antigenes
oligomerization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005025647T
Other languages
English (en)
Inventor
Barbara Capecchi
Vega Masignani
Rino Rappuoli
Maria Scarselli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Vaccines SRL
Original Assignee
Novartis Vaccines and Diagnostics SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines and Diagnostics SRL filed Critical Novartis Vaccines and Diagnostics SRL
Publication of DE602005025647D1 publication Critical patent/DE602005025647D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
DE602005025647T 2004-07-23 2005-07-22 Polypeptide für die oligomerisierung von antigenen Active DE602005025647D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59064804P 2004-07-23 2004-07-23
PCT/IB2005/002528 WO2006011060A2 (en) 2004-07-23 2005-07-22 Polypeptides for oligomeric assembly of antigens

Publications (1)

Publication Number Publication Date
DE602005025647D1 true DE602005025647D1 (de) 2011-02-10

Family

ID=35447945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005025647T Active DE602005025647D1 (de) 2004-07-23 2005-07-22 Polypeptide für die oligomerisierung von antigenen

Country Status (8)

Country Link
US (1) US7915218B2 (de)
EP (1) EP1778725B1 (de)
CN (1) CN101014618B (de)
AT (1) ATE493437T1 (de)
CA (1) CA2574375C (de)
DE (1) DE602005025647D1 (de)
ES (1) ES2355980T3 (de)
WO (1) WO2006011060A2 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9808932D0 (en) * 1998-04-27 1998-06-24 Chiron Spa Polyepitope carrier protein
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
EP1848732B1 (de) 2005-01-21 2016-07-27 Epitopix, LLC Yersinia spp. polypeptide und verwendungsverfahren
US20070042001A1 (en) * 2005-08-16 2007-02-22 Hawaii Biotech, Inc. Influenza recombinant subunit vaccine
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
EP1972350A1 (de) * 2007-03-20 2008-09-24 Rijksuniversiteit Groningen Duales Targeting-System
EA200700940A1 (ru) * 2007-04-27 2007-12-28 Петр Генриевич ЛОХОВ Способ получения противоопухолевой вакцины на основе поверхностных антигенов эндотелиальных клеток
EP2003144A1 (de) * 2007-06-15 2008-12-17 Institut Pasteur Diagnose- oder Screening-Verfahren für eine Arbovirusinfektion, Reagenzien für dieses Verfahren und deren Anwendung
GB0711858D0 (en) * 2007-06-19 2007-07-25 Glaxosmithkline Biolog Sa Vaccine
US8642046B2 (en) * 2007-10-09 2014-02-04 Tufts University Cholera vaccines
JP5261775B2 (ja) * 2008-02-22 2013-08-14 国立大学法人名古屋大学 微生物に対して非特異的付着性及び／又は凝集性を付与又は増強する方法及び遺伝子
EP4218800A1 (de) 2009-07-15 2023-08-02 GlaxoSmithKline Biologicals S.A. Rsv-f-proteinzusammensetzungen und verfahren zur herstellung davon
PT3246044T (pt) 2010-08-23 2021-02-15 Wyeth Llc Formulações estáveis de antigénios de rlp2086 de neisseria meningitidis
MX362802B (es) 2010-09-10 2019-02-13 Wyeth Llc Star Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis.
LT2707385T (lt) 2011-05-13 2017-12-11 Glaxosmithkline Biologicals Sa Iš anksto sulieti rsv f antigenai
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
CA2865745C (en) 2012-03-09 2018-01-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
US20150050311A1 (en) * 2012-04-05 2015-02-19 Ludwig-Maximilians-Universitat München Novel method for the preparation of a strain-adapted vaccine
BR112015001390A2 (pt) * 2012-07-26 2017-09-26 Henry M Jackson Found Advancement Military Medicine Inc vacina de proteína de fusão multimérica e imunoterápicos
WO2014016152A1 (en) 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
JP6446377B2 (ja) 2013-03-08 2018-12-26 ファイザー・インク 免疫原性融合ポリペプチド
MX369534B (es) 2013-09-08 2019-11-11 Pfizer Composiciones de neisseria meningitidis y sus metodos.
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
RU2723045C2 (ru) 2015-02-19 2020-06-08 Пфайзер Инк. Композиции neisseria meningitidis и способы их получения
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US10183070B2 (en) 2017-01-31 2019-01-22 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
WO2021188818A1 (en) * 2020-03-19 2021-09-23 The United States Of America As Represented By The Secretary Of The Navy Vaccine constructs and compositions and methods of use thereof
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

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GB9106048D0 (en) * 1991-03-21 1991-05-08 Smithkline Beecham Biolog Vaccines
US5837544A (en) 1995-02-02 1998-11-17 Cell Genesys, Inc. Method of inducing a cell to proliferate using a chimeric receptor comprising janus kinase
US6716429B1 (en) * 1997-10-01 2004-04-06 Dana-Farber Cancer Institute, Inc. Stabilization of envelope glycoprotein trimers by disulfide bonds introduced into a gp 41 glycoprotein ectodomain
EP1365027A4 (de) * 2000-05-26 2005-06-22 Mochida Pharm Co Ltd Mit fas-liganden fusioniertes protein

Also Published As

Publication number Publication date
EP1778725A2 (de) 2007-05-02
ES2355980T3 (es) 2011-04-01
CA2574375A1 (en) 2006-02-02
WO2006011060A2 (en) 2006-02-02
WO2006011060A3 (en) 2006-04-06
ATE493437T1 (de) 2011-01-15
EP1778725B1 (de) 2010-12-29
US20080260769A1 (en) 2008-10-23
CN101014618A (zh) 2007-08-08
CN101014618B (zh) 2013-01-02
CA2574375C (en) 2015-03-17
US7915218B2 (en) 2011-03-29

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