DE602005014473D1 - Amino-propanolderivate - Google Patents
Amino-propanolderivateInfo
- Publication number
- DE602005014473D1 DE602005014473D1 DE602005014473T DE602005014473T DE602005014473D1 DE 602005014473 D1 DE602005014473 D1 DE 602005014473D1 DE 602005014473 T DE602005014473 T DE 602005014473T DE 602005014473 T DE602005014473 T DE 602005014473T DE 602005014473 D1 DE602005014473 D1 DE 602005014473D1
- Authority
- DE
- Germany
- Prior art keywords
- propanolderivate
- amino
- transplantation
- processes
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/094—Esters of phosphoric acids with arylalkanols
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0411929.3A GB0411929D0 (en) | 2004-05-27 | 2004-05-27 | Organic compounds |
PCT/EP2005/005685 WO2005118523A1 (en) | 2004-05-27 | 2005-05-25 | Amino-propanol derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005014473D1 true DE602005014473D1 (en) | 2009-06-25 |
Family
ID=32671206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005014473T Active DE602005014473D1 (en) | 2004-05-27 | 2005-05-25 | Amino-propanolderivate |
Country Status (17)
Country | Link |
---|---|
US (1) | US7928093B2 (de) |
EP (1) | EP1753712B1 (de) |
JP (1) | JP4490482B2 (de) |
KR (1) | KR100837897B1 (de) |
CN (1) | CN100575335C (de) |
AT (1) | ATE431333T1 (de) |
AU (1) | AU2005250112B2 (de) |
BR (1) | BRPI0511610A (de) |
CA (1) | CA2562332A1 (de) |
DE (1) | DE602005014473D1 (de) |
ES (1) | ES2327250T3 (de) |
GB (1) | GB0411929D0 (de) |
MX (1) | MXPA06013624A (de) |
PL (1) | PL1753712T3 (de) |
PT (1) | PT1753712E (de) |
RU (1) | RU2006146215A (de) |
WO (1) | WO2005118523A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2004234067B2 (en) * | 2003-04-30 | 2008-02-28 | Novartis Ag | Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators |
WO2005041899A2 (en) | 2003-11-03 | 2005-05-12 | University Of Virginia Patent Foundation | Orally available sphingosine 1-phosphate receptor agonists and antagonists |
CN101905023B (zh) * | 2004-07-16 | 2012-07-11 | 杏林制药株式会社 | 有效的医药使用方法及与副作用发生的防御相关的方法 |
EP1781595A1 (de) | 2004-08-13 | 2007-05-09 | Praecis Pharmaceuticals Inc. | Verfahren und zusammensetzungen zur modulation von sphingosin-1-phosphat-rezeptoraktivität |
US7795472B2 (en) * | 2004-10-12 | 2010-09-14 | Kyorin Pharmaceutical Co., Ltd. | Process for producing 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl]-1,3-propanediol hydrochloride and hydrates thereof, and intermediates in the production thereof |
MX2007006706A (es) | 2004-12-06 | 2007-10-18 | Univ Virginia | Analogos de esfingosina 1-fosfato amida de arilo. |
US8048928B2 (en) * | 2005-10-07 | 2011-11-01 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent for treating liver disease containing 2-amino-1,3-propanediol derivative as active ingredient, and method for treating liver disease |
RU2008134702A (ru) | 2006-01-27 | 2010-03-10 | Юниверсити Оф Вирждиния Пэтент Фаундейшн (Us) | Способ лечения невропатической боли |
TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
EP1987013A1 (de) * | 2006-02-09 | 2008-11-05 | University Of Virginia Patent Foundation | Bicyclische sphingosin-1-phosphat-analoge |
NZ574011A (en) * | 2006-08-08 | 2011-10-28 | Kyorin Seiyaku Kk | Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient |
SG174029A1 (en) | 2006-08-08 | 2011-09-29 | Kyorin Seiyaku Kk | Aminoalcohol derivative and immunosuppressant containing the same as active ingredient |
NZ576893A (en) | 2006-11-21 | 2012-01-12 | Univ Virginia Patent Found | Tetralin analogs having sphingosine 1-phosphate agonist activity |
CA2669124A1 (en) | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Benzocycloheptyl analogs having sphingosine 1-phosphate receptor activity |
EP2099741A2 (de) | 2006-11-21 | 2009-09-16 | University Of Virginia Patent Foundation | Hydrindan-analoga mit sphingosin-1-phosphatrezeptoragonistenaktivität |
WO2008124210A1 (en) * | 2007-02-14 | 2008-10-16 | Emory University | Methods and compositions for treating or preventing infection using leukocyte sequestration agents |
WO2009099174A1 (ja) | 2008-02-07 | 2009-08-13 | Kyorin Pharmaceutical Co., Ltd. | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
AR074062A1 (es) * | 2008-10-31 | 2010-12-22 | Lexicon Pharmaceuticals Inc | Agonistas del receptor s1p para el tratamiento de la malaria cerebral y forma farmaceutica |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5948820A (en) * | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
ATE211726T1 (de) | 1994-08-22 | 2002-01-15 | Welfide Corp | Benzolderivate und deren medizinische verwendung |
KR100551931B1 (ko) * | 1997-04-04 | 2006-02-16 | 미츠비시 웰파마 가부시키가이샤 | 2-아미노프로판-1,3-디올 화합물, 이것의 의약으로서의 용도 및 합성 중간체 |
WO2002076995A2 (en) | 2001-03-26 | 2002-10-03 | Novartis Ag | 2-amino-propanol derivatives |
JP4166218B2 (ja) * | 2002-09-13 | 2008-10-15 | ノバルティス アクチエンゲゼルシャフト | アミノ−プロパノール誘導体 |
AU2004234067B2 (en) * | 2003-04-30 | 2008-02-28 | Novartis Ag | Aminopropanol derivatives as sphingosine-1-phosphate receptor modulators |
-
2004
- 2004-05-27 GB GBGB0411929.3A patent/GB0411929D0/en not_active Ceased
-
2005
- 2005-05-25 CN CN200580012823A patent/CN100575335C/zh not_active Expired - Fee Related
- 2005-05-25 BR BRPI0511610-4A patent/BRPI0511610A/pt not_active IP Right Cessation
- 2005-05-25 PT PT05752742T patent/PT1753712E/pt unknown
- 2005-05-25 RU RU2006146215/04A patent/RU2006146215A/ru not_active Application Discontinuation
- 2005-05-25 PL PL05752742T patent/PL1753712T3/pl unknown
- 2005-05-25 AU AU2005250112A patent/AU2005250112B2/en not_active Ceased
- 2005-05-25 AT AT05752742T patent/ATE431333T1/de active
- 2005-05-25 KR KR1020067024709A patent/KR100837897B1/ko not_active IP Right Cessation
- 2005-05-25 DE DE602005014473T patent/DE602005014473D1/de active Active
- 2005-05-25 CA CA002562332A patent/CA2562332A1/en not_active Abandoned
- 2005-05-25 ES ES05752742T patent/ES2327250T3/es active Active
- 2005-05-25 EP EP05752742A patent/EP1753712B1/de not_active Not-in-force
- 2005-05-25 US US11/568,645 patent/US7928093B2/en not_active Expired - Fee Related
- 2005-05-25 JP JP2007513805A patent/JP4490482B2/ja not_active Expired - Fee Related
- 2005-05-25 WO PCT/EP2005/005685 patent/WO2005118523A1/en active Application Filing
- 2005-05-25 MX MXPA06013624A patent/MXPA06013624A/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR20070015439A (ko) | 2007-02-02 |
PT1753712E (pt) | 2009-08-06 |
PL1753712T3 (pl) | 2009-10-30 |
AU2005250112A1 (en) | 2005-12-15 |
JP4490482B2 (ja) | 2010-06-23 |
JP2008500302A (ja) | 2008-01-10 |
MXPA06013624A (es) | 2007-02-28 |
ATE431333T1 (de) | 2009-05-15 |
RU2006146215A (ru) | 2008-07-10 |
US20070225260A1 (en) | 2007-09-27 |
CA2562332A1 (en) | 2005-12-15 |
WO2005118523A1 (en) | 2005-12-15 |
BRPI0511610A (pt) | 2008-01-02 |
ES2327250T3 (es) | 2009-10-27 |
GB0411929D0 (en) | 2004-06-30 |
CN1946679A (zh) | 2007-04-11 |
CN100575335C (zh) | 2009-12-30 |
KR100837897B1 (ko) | 2008-06-13 |
AU2005250112B2 (en) | 2009-01-08 |
EP1753712B1 (de) | 2009-05-13 |
US7928093B2 (en) | 2011-04-19 |
EP1753712A1 (de) | 2007-02-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE602005014473D1 (en) | Amino-propanolderivate | |
MXPA05011597A (es) | Derivados de aminopropanol como moduladores del receptor 1-fosfato de esfingosina. | |
TW200617009A (en) | Organic compounds | |
PL1904482T3 (pl) | Pochodne indolilomaleimidowe | |
TW200732335A (en) | Organic compounds | |
DE602004024213D1 (en) | Aminopropanolderivate | |
MX2009012082A (es) | Compuestos de ariloazol-2-il cianoetilamino, metodo para prepararlos y metodo para utilizarlos. | |
HK1125358A1 (en) | Substituted cyclohexylmethyl derivatives | |
MX2007005933A (es) | Compuestos de acetamida como fungicidas. | |
TW200611904A (en) | Aza-bicyclononanes | |
TW200635921A (en) | Organic compounds | |
MXPA05011596A (es) | Derivados de amino-propanol como modulador de receptor de esfingosina-1-fosfato. | |
TW200637837A (en) | Fungicides | |
TW200801003A (en) | Novel compounds | |
TW200732337A (en) | Organic compounds | |
TW200745067A (en) | Novel compounds | |
JO2734B1 (en) | Organic compounds | |
TW200745084A (en) | Novel compounds | |
MXPA05013348A (es) | Derivados de amino-propanol como moduladores del receptor de esfingosina-1-fosfato. | |
MX2009006533A (es) | Derivados de indolil-maleimida como inhibidores de cinasa. | |
GB0508314D0 (en) | Organic compounds | |
GEP20084361B (en) | Piperidinylcarbonyl-pyrro-lidines and their use as melanocortin agonists | |
SE0401762D0 (sv) | Novel compounds | |
TW200635917A (en) | Novel compounds | |
TW200740781A (en) | Novel compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |