DE602005013923D1 - Derivate von piperidinylalkylcarbamaten, herstellungsverfahren davon und verwendung derselben als faah-enzym-inhibitoren - Google Patents
Derivate von piperidinylalkylcarbamaten, herstellungsverfahren davon und verwendung derselben als faah-enzym-inhibitorenInfo
- Publication number
- DE602005013923D1 DE602005013923D1 DE602005013923T DE602005013923T DE602005013923D1 DE 602005013923 D1 DE602005013923 D1 DE 602005013923D1 DE 602005013923 T DE602005013923 T DE 602005013923T DE 602005013923 T DE602005013923 T DE 602005013923T DE 602005013923 D1 DE602005013923 D1 DE 602005013923D1
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- DE
- Germany
- Prior art keywords
- derivatives
- manufacturing
- enzyme inhibitors
- alkyl carbamates
- faah enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
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- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- Anesthesiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0401952A FR2866885B1 (fr) | 2004-02-26 | 2004-02-26 | Derives de piperidinylalkylcarbamates, leur prepation et leur application en therapeutique |
PCT/FR2005/000452 WO2005089759A1 (fr) | 2004-02-26 | 2005-02-25 | Derives de piperidinylalkylcarbamates, leur preparation et leur application comme inhibiteurs de l’enzyme faah |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005013923D1 true DE602005013923D1 (de) | 2009-05-28 |
Family
ID=34834069
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005013923T Active DE602005013923D1 (de) | 2004-02-26 | 2005-02-25 | Derivate von piperidinylalkylcarbamaten, herstellungsverfahren davon und verwendung derselben als faah-enzym-inhibitoren |
Country Status (26)
Country | Link |
---|---|
US (2) | US7781590B2 (de) |
EP (1) | EP1720550B1 (de) |
JP (1) | JP4796046B2 (de) |
KR (1) | KR20060134081A (de) |
CN (1) | CN1921858A (de) |
AR (1) | AR047818A1 (de) |
AT (1) | ATE428417T1 (de) |
AU (1) | AU2005224140B2 (de) |
BR (1) | BRPI0508072A (de) |
CA (1) | CA2554608A1 (de) |
CY (1) | CY1109231T1 (de) |
DE (1) | DE602005013923D1 (de) |
DK (1) | DK1720550T3 (de) |
ES (1) | ES2325376T3 (de) |
FR (1) | FR2866885B1 (de) |
HR (1) | HRP20090294T1 (de) |
IL (1) | IL177534A (de) |
MA (1) | MA28366A1 (de) |
NZ (1) | NZ550007A (de) |
PL (1) | PL1720550T3 (de) |
PT (1) | PT1720550E (de) |
RU (1) | RU2384569C2 (de) |
SI (1) | SI1720550T1 (de) |
TW (1) | TW200529816A (de) |
WO (1) | WO2005089759A1 (de) |
ZA (1) | ZA200606964B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2866888B1 (fr) * | 2004-02-26 | 2006-05-05 | Sanofi Synthelabo | Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en therapeutique |
FR2866884B1 (fr) * | 2004-02-26 | 2007-08-31 | Sanofi Synthelabo | Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique |
FR2866886B1 (fr) * | 2004-02-26 | 2007-08-31 | Sanofi Synthelabo | Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique |
WO2007005510A1 (en) | 2005-06-30 | 2007-01-11 | Janssen Pharmaceutica N.V. | N-heteroarylpiperazinyl ureas as modulators of fatty acid amide hydrolase |
EP1954137A4 (de) * | 2005-11-18 | 2008-12-17 | Janssen Pharmaceutica Nv | 2-keto-oxazole als modulatoren der fettsäureamidhydrolase |
WO2007070760A2 (en) | 2005-12-15 | 2007-06-21 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
CA2657247A1 (en) | 2006-07-28 | 2008-01-31 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
BRPI0718515A2 (pt) | 2006-09-25 | 2013-11-19 | Boehringer Ingelheim Int | Compostos que modulam o receptor cb2 |
CA2704684A1 (en) | 2007-11-07 | 2009-05-14 | Boehringer Ingelheim International Gmbh | Compounds which modulate the cb2 receptor |
CA2730037A1 (en) | 2008-07-10 | 2010-01-14 | Boehringer Ingelheim International Gmbh | Sulfone compounds which modulate the cb2 receptor |
PE20110397A1 (es) | 2008-09-25 | 2011-07-01 | Boehringer Ingelheim Int | Compuestos que modulan selectivamente el receptor cb2 |
FR2941696B1 (fr) * | 2009-02-05 | 2011-04-15 | Sanofi Aventis | Derives d'azaspiranyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique |
FR2945531A1 (fr) * | 2009-05-12 | 2010-11-19 | Sanofi Aventis | Derives de 7-aza-spiro°3,5!nonane-7-carboxylates, leur preparation et leur application en therapeutique |
US8299103B2 (en) | 2009-06-15 | 2012-10-30 | Boehringer Ingelheim International Gmbh | Compounds which selectively modulate the CB2 receptor |
WO2010147791A1 (en) | 2009-06-16 | 2010-12-23 | Boehringer Ingelheim International Gmbh | Azetidine 2 -carboxamide derivatives which modulate the cb2 receptor |
JP2013505295A (ja) | 2009-09-22 | 2013-02-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を選択的に調節する化合物 |
JP2013517271A (ja) | 2010-01-15 | 2013-05-16 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を調節する化合物 |
JP5746228B2 (ja) | 2010-03-05 | 2015-07-08 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Cb2受容体を選択的に調節するテトラゾール化合物 |
US8846936B2 (en) | 2010-07-22 | 2014-09-30 | Boehringer Ingelheim International Gmbh | Sulfonyl compounds which modulate the CB2 receptor |
EP2803668A1 (de) | 2013-05-17 | 2014-11-19 | Boehringer Ingelheim International Gmbh | Neuartige (Cyano-dimethyl-methyl)-isoxazole und -[1,3,4]-thiadiazole |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3235565A1 (de) * | 1982-09-25 | 1984-03-29 | Boehringer Ingelheim KG, 6507 Ingelheim | Piperidinderivate, ihre herstellung und verwendung |
DE69833791D1 (de) * | 1997-11-24 | 2006-05-04 | Scripps Research Inst | Hemmer der "gap junction communication" |
WO2002087569A1 (en) * | 2001-04-27 | 2002-11-07 | Bristol-Myers Squibb Company | Bisarylimidazolyl fatty acid amide hydrolase inhibitors |
US6949574B2 (en) * | 2002-02-08 | 2005-09-27 | Bristol-Myers Squibb Company | (Oxime)carbamoyl fatty acid amide hydrolase inhibitors |
FR2843964B1 (fr) * | 2002-08-29 | 2004-10-01 | Sanofi Synthelabo | Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique |
FR2850377B1 (fr) * | 2003-01-23 | 2009-02-20 | Sanofi Synthelabo | Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique |
FR2854633B1 (fr) * | 2003-05-07 | 2005-06-24 | Sanofi Synthelabo | Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique |
FR2860514A1 (fr) * | 2003-10-03 | 2005-04-08 | Sanofi Synthelabo | Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique |
FR2866886B1 (fr) * | 2004-02-26 | 2007-08-31 | Sanofi Synthelabo | Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique |
-
2004
- 2004-02-26 FR FR0401952A patent/FR2866885B1/fr not_active Expired - Fee Related
-
2005
- 2005-02-24 AR ARP050100668A patent/AR047818A1/es unknown
- 2005-02-25 JP JP2007500261A patent/JP4796046B2/ja not_active Expired - Fee Related
- 2005-02-25 ES ES05732905T patent/ES2325376T3/es active Active
- 2005-02-25 PT PT05732905T patent/PT1720550E/pt unknown
- 2005-02-25 TW TW094105855A patent/TW200529816A/zh unknown
- 2005-02-25 DK DK05732905T patent/DK1720550T3/da active
- 2005-02-25 BR BRPI0508072-0A patent/BRPI0508072A/pt not_active IP Right Cessation
- 2005-02-25 CN CNA2005800058637A patent/CN1921858A/zh active Pending
- 2005-02-25 SI SI200530727T patent/SI1720550T1/sl unknown
- 2005-02-25 RU RU2006134025/04A patent/RU2384569C2/ru not_active IP Right Cessation
- 2005-02-25 EP EP05732905A patent/EP1720550B1/de active Active
- 2005-02-25 PL PL05732905T patent/PL1720550T3/pl unknown
- 2005-02-25 CA CA002554608A patent/CA2554608A1/fr not_active Abandoned
- 2005-02-25 KR KR1020067017251A patent/KR20060134081A/ko active IP Right Grant
- 2005-02-25 ZA ZA200606964A patent/ZA200606964B/xx unknown
- 2005-02-25 AT AT05732905T patent/ATE428417T1/de active
- 2005-02-25 NZ NZ550007A patent/NZ550007A/en unknown
- 2005-02-25 DE DE602005013923T patent/DE602005013923D1/de active Active
- 2005-02-25 WO PCT/FR2005/000452 patent/WO2005089759A1/fr active Application Filing
- 2005-02-25 AU AU2005224140A patent/AU2005224140B2/en not_active Ceased
-
2006
- 2006-08-16 IL IL177534A patent/IL177534A/en not_active IP Right Cessation
- 2006-08-21 US US11/465,825 patent/US7781590B2/en not_active Expired - Fee Related
- 2006-08-22 MA MA29284A patent/MA28366A1/fr unknown
-
2009
- 2009-05-20 HR HR20090294T patent/HRP20090294T1/xx unknown
- 2009-07-14 CY CY20091100744T patent/CY1109231T1/el unknown
-
2010
- 2010-07-12 US US12/834,267 patent/US20100279998A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
RU2006134025A (ru) | 2008-04-10 |
KR20060134081A (ko) | 2006-12-27 |
MA28366A1 (fr) | 2006-12-01 |
EP1720550A1 (de) | 2006-11-15 |
EP1720550B1 (de) | 2009-04-15 |
CY1109231T1 (el) | 2014-07-02 |
JP2007524706A (ja) | 2007-08-30 |
BRPI0508072A (pt) | 2007-07-17 |
AU2005224140A1 (en) | 2005-09-29 |
US7781590B2 (en) | 2010-08-24 |
FR2866885B1 (fr) | 2007-08-31 |
HRP20090294T1 (en) | 2009-06-30 |
US20100279998A1 (en) | 2010-11-04 |
CN1921858A (zh) | 2007-02-28 |
IL177534A0 (en) | 2006-12-10 |
PL1720550T3 (pl) | 2009-09-30 |
AR047818A1 (es) | 2006-02-22 |
CA2554608A1 (fr) | 2005-09-29 |
US20070021403A1 (en) | 2007-01-25 |
TW200529816A (en) | 2005-09-16 |
SI1720550T1 (sl) | 2009-10-31 |
JP4796046B2 (ja) | 2011-10-19 |
ES2325376T3 (es) | 2009-09-02 |
PT1720550E (pt) | 2009-06-04 |
IL177534A (en) | 2011-01-31 |
AU2005224140B2 (en) | 2010-12-02 |
WO2005089759A1 (fr) | 2005-09-29 |
FR2866885A1 (fr) | 2005-09-02 |
NZ550007A (en) | 2010-06-25 |
ATE428417T1 (de) | 2009-05-15 |
DK1720550T3 (da) | 2009-08-10 |
ZA200606964B (en) | 2008-01-30 |
RU2384569C2 (ru) | 2010-03-20 |
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