DE602005008402D1 - Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole - Google Patents

Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole

Info

Publication number
DE602005008402D1
DE602005008402D1 DE602005008402T DE602005008402T DE602005008402D1 DE 602005008402 D1 DE602005008402 D1 DE 602005008402D1 DE 602005008402 T DE602005008402 T DE 602005008402T DE 602005008402 T DE602005008402 T DE 602005008402T DE 602005008402 D1 DE602005008402 D1 DE 602005008402D1
Authority
DE
Germany
Prior art keywords
stereoselective synthesis
substituted alcohols
trifluoromethyl substituted
sup
certain trifluoromethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005008402T
Other languages
English (en)
Inventor
Jinhua J Song
Zhulin Tan
Nathan K Yee
Chris Hugh Senanayake
Jinghua Xu
Fabrice Gallou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharmaceuticals Inc
Publication of DE602005008402D1 publication Critical patent/DE602005008402D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE602005008402T 2004-03-18 2005-03-04 Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole Active DE602005008402D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55426604P 2004-03-18 2004-03-18
PCT/US2005/006998 WO2005090343A1 (en) 2004-03-18 2005-03-04 Stereoselective synthesis of certain trifluoromethyl-substituted alcohols

Publications (1)

Publication Number Publication Date
DE602005008402D1 true DE602005008402D1 (de) 2008-09-04

Family

ID=34962572

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005008402T Active DE602005008402D1 (de) 2004-03-18 2005-03-04 Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole

Country Status (8)

Country Link
US (1) US7179919B2 (de)
EP (1) EP1727818B1 (de)
JP (1) JP4672720B2 (de)
AT (1) ATE402173T1 (de)
CA (1) CA2557896A1 (de)
DE (1) DE602005008402D1 (de)
ES (1) ES2310815T3 (de)
WO (1) WO2005090343A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1490062E (pt) * 2002-03-26 2008-01-30 Boehringer Ingelheim Pharma Miméticos de glucocorticóides, métodos para a sua preparação, composições farmacêuticas e suas utilizações
US20040097574A1 (en) * 2002-08-29 2004-05-20 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
UY28526A1 (es) * 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
JP4638438B2 (ja) 2003-10-08 2011-02-23 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト テトラヒドロナフタレン誘導体類、それらの生成方法及び抗−炎症剤としてのそれらの使用
US7638515B2 (en) 2003-10-08 2009-12-29 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
US7662821B2 (en) 2003-10-08 2010-02-16 Bayer Schering Pharma Ag Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
US7795272B2 (en) * 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
US20080153859A1 (en) 2004-04-05 2008-06-26 Hartmut Rehwinkel Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
DE102004055633A1 (de) * 2004-11-12 2006-05-18 Schering Ag 5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
US7417056B2 (en) 2004-11-12 2008-08-26 Schering Ag 5-substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents
EP1836166B1 (de) * 2004-12-27 2009-06-17 Boehringer Ingelheim Pharmaceuticals Inc. Glucocorticoid-mimetika, verfahren zu deren herstellung, pharmazeutische zusammensetzungen und deren verwendung
ES2333820T3 (es) 2005-09-30 2010-03-01 Boehringer Ingelheim International Gmbh Sintesis estereoselectiva de determinados alcoholes trifluorometilo-sustituidos.
EP1834948A1 (de) 2006-03-15 2007-09-19 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer
BRPI0720131A2 (pt) * 2006-12-06 2014-02-04 Boehringer Ingelheim Int Glicocorticoides miméticos, métodos para fazê-los, composições farmacêuticas e usos dos mesmos.
WO2009149139A1 (en) * 2008-06-06 2009-12-10 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US20110130567A1 (en) * 2009-06-03 2011-06-02 Boehringer Ingelheim International Gmbh Steroselective synthesis of certain trifluoromethyl-substituted alcohols
US20220231268A1 (en) * 2019-02-06 2022-07-21 L'air Liquide, Société Anonyme Pour L'etude Et L'exploitation Des Precédés Georges Claude Compound and method for producing lithium-containing film

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1490062E (pt) 2002-03-26 2008-01-30 Boehringer Ingelheim Pharma Miméticos de glucocorticóides, métodos para a sua preparação, composições farmacêuticas e suas utilizações

Also Published As

Publication number Publication date
ES2310815T3 (es) 2009-01-16
EP1727818A1 (de) 2006-12-06
JP4672720B2 (ja) 2011-04-20
US20050209488A1 (en) 2005-09-22
JP2007529520A (ja) 2007-10-25
WO2005090343A1 (en) 2005-09-29
CA2557896A1 (en) 2005-09-29
EP1727818B1 (de) 2008-07-23
US7179919B2 (en) 2007-02-20
ATE402173T1 (de) 2008-08-15

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