DE602005008029D1 - Verfahren zum abspalten exocyclischer basenschutzgruppen - Google Patents

Verfahren zum abspalten exocyclischer basenschutzgruppen

Info

Publication number
DE602005008029D1
DE602005008029D1 DE602005008029T DE602005008029T DE602005008029D1 DE 602005008029 D1 DE602005008029 D1 DE 602005008029D1 DE 602005008029 T DE602005008029 T DE 602005008029T DE 602005008029 T DE602005008029 T DE 602005008029T DE 602005008029 D1 DE602005008029 D1 DE 602005008029D1
Authority
DE
Germany
Prior art keywords
spoking
procedure
protection groups
nucleotide
base protection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005008029T
Other languages
English (en)
Inventor
Nanda Dulal Sinha
Satya Kuchimanchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitto Denko Avecia Inc
Original Assignee
Avecia Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Biotechnology Inc filed Critical Avecia Biotechnology Inc
Publication of DE602005008029D1 publication Critical patent/DE602005008029D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Materials For Medical Uses (AREA)
DE602005008029T 2004-04-19 2005-04-15 Verfahren zum abspalten exocyclischer basenschutzgruppen Active DE602005008029D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56301304P 2004-04-19 2004-04-19
PCT/GB2005/001436 WO2005100375A1 (en) 2004-04-19 2005-04-15 Process for the removal of exocyclic base protecting groups

Publications (1)

Publication Number Publication Date
DE602005008029D1 true DE602005008029D1 (de) 2008-08-21

Family

ID=34965370

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005008029T Active DE602005008029D1 (de) 2004-04-19 2005-04-15 Verfahren zum abspalten exocyclischer basenschutzgruppen

Country Status (5)

Country Link
US (1) US7872121B2 (de)
EP (1) EP1737877B1 (de)
AT (1) ATE400579T1 (de)
DE (1) DE602005008029D1 (de)
WO (1) WO2005100375A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013520395A (ja) * 2009-02-22 2013-06-06 ケムジーンズ コーポレーション 治療、診断、ｇ‐テトラド形成オリゴヌクレオシド及びアプタマーといった生物学的応用のための新規修飾を取り入れたアラ‐２’‐ｏ‐メチル‐ヌクレオシド、当該ホスホラミダイト及びオリゴヌクレオチドの合成

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2682112B1 (fr) * 1991-10-08 1993-12-10 Commissariat A Energie Atomique Procede de synthese d'acide ribonucleique (arn) utilisant un nouveau reactif de deprotection.
US5808039A (en) * 1995-10-18 1998-09-15 Beckman Instruments, Inc. 2'-OMe CAC phosphoramidite and methods for preparation and use thereof
DE60207995T2 (de) * 2001-03-08 2006-08-03 Applera Corp., Foster City Verfahren zum entschützen von oligonukleotiden

Also Published As

Publication number Publication date
EP1737877A1 (de) 2007-01-03
ATE400579T1 (de) 2008-07-15
US20090221810A1 (en) 2009-09-03
EP1737877B1 (de) 2008-07-09
WO2005100375A1 (en) 2005-10-27
US7872121B2 (en) 2011-01-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition