DE602005007241D1 - 2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeit - Google Patents

2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeit

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Publication number
DE602005007241D1
DE602005007241D1 DE602005007241T DE602005007241T DE602005007241D1 DE 602005007241 D1 DE602005007241 D1 DE 602005007241D1 DE 602005007241 T DE602005007241 T DE 602005007241T DE 602005007241 T DE602005007241 T DE 602005007241T DE 602005007241 D1 DE602005007241 D1 DE 602005007241D1
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Germany
Prior art keywords
channels
modulators
amino
calcium
activated
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DE602005007241T
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English (en)
Inventor
Ulrik Svane Soerensen
Lene Teuber
Dan Peters
Dorte Stroebak
Tina Holm Johansen
Karin Sandager Nielsen
Palle Christophersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
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Neurosearch AS
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Publication of DE602005007241D1 publication Critical patent/DE602005007241D1/de
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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DE602005007241T 2004-08-05 2005-08-03 2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeit Active DE602005007241D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200401191 2004-08-05
US59902504P 2004-08-06 2004-08-06
PCT/EP2005/053792 WO2006013210A2 (en) 2004-08-05 2005-08-03 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels

Publications (1)

Publication Number Publication Date
DE602005007241D1 true DE602005007241D1 (de) 2008-07-10

Family

ID=35508344

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005007241T Active DE602005007241D1 (de) 2004-08-05 2005-08-03 2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeit

Country Status (9)

Country Link
US (1) US7737167B2 (de)
EP (1) EP1776348B1 (de)
JP (1) JP2008509111A (de)
AT (1) ATE396977T1 (de)
AU (1) AU2005268782A1 (de)
CA (1) CA2575882A1 (de)
DE (1) DE602005007241D1 (de)
MX (1) MX2007001325A (de)
WO (1) WO2006013210A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120309796A1 (en) 2011-06-06 2012-12-06 Fariborz Firooznia Benzocycloheptene acetic acids
CN102718663A (zh) * 2012-06-21 2012-10-10 台州市华南医化有限公司 一种5-氯-1-茚胺的合成方法
CN109153667B (zh) 2016-02-24 2021-04-02 阿塞西翁制药公司 新型钾通道抑制剂
EP3668841A1 (de) 2017-08-14 2020-06-24 Acesion Pharma ApS Substituierte benzimidazole als kaliumkanalinhibitoren
CN111372928B (zh) 2017-08-23 2023-05-16 阿塞西翁制药公司 用作钾通道抑制剂的苯并咪唑衍生物
CA3211188A1 (en) 2021-03-22 2022-09-29 Acesion Pharma Aps Novel potassium channel inhibitors
EP4245753A1 (de) 2022-03-17 2023-09-20 Acesion Pharma ApS Imidazolderivate als kaliumkanalinhibitoren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1091942B1 (de) * 1998-07-02 2005-03-30 Neurosearch A/S Kaliumkanal-blockierende mittel
DE60020556T2 (de) 1999-05-12 2005-10-27 Neurosearch A/S Ionenkanal modulierende mittel
EP1196419B1 (de) 1999-06-29 2003-09-24 Neurosearch A/S Kaliumkanal-blockierende mittel
WO2003094861A2 (en) 2002-05-13 2003-11-20 Icagen, Inc. Bis-benzimidazoles and related compounds as potassium channel modulators
WO2004035056A1 (en) 2002-10-13 2004-04-29 Neurosearch A/S Use of skca channel blocking drugs for combating parkinson's disease
US20090131503A1 (en) * 2007-11-16 2009-05-21 Annedi Subhash C 3,5 - substituted indole compounds having nos and norepinephrine reuptake inhibitory activity

Also Published As

Publication number Publication date
CA2575882A1 (en) 2006-02-09
WO2006013210A2 (en) 2006-02-09
ATE396977T1 (de) 2008-06-15
EP1776348B1 (de) 2008-05-28
WO2006013210A3 (en) 2006-05-04
MX2007001325A (es) 2008-03-13
US7737167B2 (en) 2010-06-15
JP2008509111A (ja) 2008-03-27
AU2005268782A1 (en) 2006-02-09
EP1776348A2 (de) 2007-04-25
US20070197618A1 (en) 2007-08-23

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