ATE396977T1 - 2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeit - Google Patents
2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeitInfo
- Publication number
- ATE396977T1 ATE396977T1 AT05776133T AT05776133T ATE396977T1 AT E396977 T1 ATE396977 T1 AT E396977T1 AT 05776133 T AT05776133 T AT 05776133T AT 05776133 T AT05776133 T AT 05776133T AT E396977 T1 ATE396977 T1 AT E396977T1
- Authority
- AT
- Austria
- Prior art keywords
- modulators
- amino
- calcium
- benzimidazole derivatives
- potassium channels
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A—HUMAN NECESSITIES
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200401191 | 2004-08-05 | ||
| US59902504P | 2004-08-06 | 2004-08-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE396977T1 true ATE396977T1 (de) | 2008-06-15 |
Family
ID=35508344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05776133T ATE396977T1 (de) | 2004-08-05 | 2005-08-03 | 2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeit |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7737167B2 (de) |
| EP (1) | EP1776348B1 (de) |
| JP (1) | JP2008509111A (de) |
| AT (1) | ATE396977T1 (de) |
| AU (1) | AU2005268782A1 (de) |
| CA (1) | CA2575882A1 (de) |
| DE (1) | DE602005007241D1 (de) |
| MX (1) | MX2007001325A (de) |
| WO (1) | WO2006013210A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120309796A1 (en) | 2011-06-06 | 2012-12-06 | Fariborz Firooznia | Benzocycloheptene acetic acids |
| CN102718663A (zh) * | 2012-06-21 | 2012-10-10 | 台州市华南医化有限公司 | 一种5-氯-1-茚胺的合成方法 |
| US11274092B2 (en) | 2016-02-24 | 2022-03-15 | Acesion Pharma Aps | Potassium channel inhibitors |
| US11098018B2 (en) | 2017-08-14 | 2021-08-24 | Acesion Pharma Aps | Potassium channel inhibitors |
| CA3072668A1 (en) * | 2017-08-23 | 2019-02-28 | Acesion Pharma Aps | Benzimidazole derivatives useful as potassium channel inhibitors |
| JP2024511101A (ja) | 2021-03-22 | 2024-03-12 | アセシオン ファーマ エイピーエス | 新規カリウムチャネル阻害剤 |
| EP4245753A1 (de) | 2022-03-17 | 2023-09-20 | Acesion Pharma ApS | Imidazolderivate als kaliumkanalinhibitoren |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002519412A (ja) | 1998-07-02 | 2002-07-02 | ニューロサーチ、アクティーゼルスカブ | カリウムチャンネル遮断剤 |
| AU4537500A (en) * | 1999-05-12 | 2000-12-05 | Neurosearch A/S | Ion channel modulating agents |
| WO2001002406A1 (en) * | 1999-06-29 | 2001-01-11 | Neurosearch A/S | Potassium channel blocking agents |
| EP1511744A4 (de) | 2002-05-13 | 2009-10-21 | Icagen Inc | Bis-benzimidazole und verwandte verbindungen als kaliumkanalmodulatoren |
| WO2004035056A1 (en) * | 2002-10-13 | 2004-04-29 | Neurosearch A/S | Use of skca channel blocking drugs for combating parkinson's disease |
| CA2705833A1 (en) * | 2007-11-16 | 2009-05-22 | Subhash C. Annedi | 3,5-substituted indole compounds having nos and norepinephrine reuptake inhibitory activity |
-
2005
- 2005-08-03 EP EP05776133A patent/EP1776348B1/de not_active Not-in-force
- 2005-08-03 JP JP2007524345A patent/JP2008509111A/ja active Pending
- 2005-08-03 CA CA002575882A patent/CA2575882A1/en not_active Abandoned
- 2005-08-03 DE DE602005007241T patent/DE602005007241D1/de active Active
- 2005-08-03 US US11/628,970 patent/US7737167B2/en not_active Expired - Fee Related
- 2005-08-03 AT AT05776133T patent/ATE396977T1/de not_active IP Right Cessation
- 2005-08-03 AU AU2005268782A patent/AU2005268782A1/en not_active Abandoned
- 2005-08-03 WO PCT/EP2005/053792 patent/WO2006013210A2/en active IP Right Grant
- 2005-08-03 MX MX2007001325A patent/MX2007001325A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1776348A2 (de) | 2007-04-25 |
| DE602005007241D1 (de) | 2008-07-10 |
| MX2007001325A (es) | 2008-03-13 |
| WO2006013210A3 (en) | 2006-05-04 |
| EP1776348B1 (de) | 2008-05-28 |
| AU2005268782A1 (en) | 2006-02-09 |
| US7737167B2 (en) | 2010-06-15 |
| JP2008509111A (ja) | 2008-03-27 |
| US20070197618A1 (en) | 2007-08-23 |
| WO2006013210A2 (en) | 2006-02-09 |
| CA2575882A1 (en) | 2006-02-09 |
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