DE602004020795D1 - Nachweis von no unter verwendung von guanylylcyclase und cgmp-produktion als readout-system - Google Patents

Nachweis von no unter verwendung von guanylylcyclase und cgmp-produktion als readout-system

Info

Publication number
DE602004020795D1
DE602004020795D1 DE602004020795T DE602004020795T DE602004020795D1 DE 602004020795 D1 DE602004020795 D1 DE 602004020795D1 DE 602004020795 T DE602004020795 T DE 602004020795T DE 602004020795 T DE602004020795 T DE 602004020795T DE 602004020795 D1 DE602004020795 D1 DE 602004020795D1
Authority
DE
Germany
Prior art keywords
guanylylcyclase
proof
readout system
cgmp production
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004020795T
Other languages
English (en)
Inventor
Frank Buettner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Publication of DE602004020795D1 publication Critical patent/DE602004020795D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE602004020795T 2003-11-26 2004-11-25 Nachweis von no unter verwendung von guanylylcyclase und cgmp-produktion als readout-system Active DE602004020795D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03027159 2003-11-26
PCT/EP2004/013707 WO2005052185A1 (en) 2003-11-26 2004-11-25 Detection of no by using guanylyl cyclase and cgmp production as a readout system

Publications (1)

Publication Number Publication Date
DE602004020795D1 true DE602004020795D1 (de) 2009-06-04

Family

ID=34626376

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004020795T Active DE602004020795D1 (de) 2003-11-26 2004-11-25 Nachweis von no unter verwendung von guanylylcyclase und cgmp-produktion als readout-system

Country Status (8)

Country Link
EP (1) EP1689880B1 (de)
JP (1) JP5671194B2 (de)
AT (1) ATE429508T1 (de)
CA (1) CA2540822C (de)
DE (1) DE602004020795D1 (de)
DK (1) DK1689880T3 (de)
ES (1) ES2324477T3 (de)
WO (1) WO2005052185A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006038942A1 (de) * 2006-08-18 2008-02-21 Bayer Healthcare Ag Verfahren zur Identifizierung von Stickstoffmonoxid Modulatoren
JP5350607B2 (ja) * 2007-06-14 2013-11-27 キッコーマン株式会社 グアニル酸シクラーゼ活性測定法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10043845A1 (de) * 2000-09-06 2002-03-14 Gruenenthal Gmbh Verfahren zur Messung der Aktivität der NO-Synthase

Also Published As

Publication number Publication date
EP1689880A1 (de) 2006-08-16
EP1689880B1 (de) 2009-04-22
JP5671194B2 (ja) 2015-02-18
JP2007512011A (ja) 2007-05-17
ATE429508T1 (de) 2009-05-15
DK1689880T3 (da) 2009-07-27
CA2540822C (en) 2010-09-21
ES2324477T3 (es) 2009-08-07
CA2540822A1 (en) 2005-06-09
WO2005052185A1 (en) 2005-06-09

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