DE602004011574D1 - Glycosylierte steroidderivate mit antimigratorischer wirkung - Google Patents
Glycosylierte steroidderivate mit antimigratorischer wirkungInfo
- Publication number
- DE602004011574D1 DE602004011574D1 DE602004011574T DE602004011574T DE602004011574D1 DE 602004011574 D1 DE602004011574 D1 DE 602004011574D1 DE 602004011574 T DE602004011574 T DE 602004011574T DE 602004011574 T DE602004011574 T DE 602004011574T DE 602004011574 D1 DE602004011574 D1 DE 602004011574D1
- Authority
- DE
- Germany
- Prior art keywords
- steroid derivatives
- glycosylated steroid
- antimigratory
- effect
- antimigratory effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0095—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 carbon in position 21 is part of carboxylic group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2003/014567 WO2004055039A1 (en) | 2002-12-18 | 2003-12-18 | Steroid compounds with anti-tumor activity |
WOPCT/EP03/14567 | 2003-12-18 | ||
EP2004006486 | 2004-06-16 | ||
WOPCT/EP2004/006 | 2004-06-16 | ||
PCT/EP2004/014408 WO2005058934A2 (en) | 2003-12-18 | 2004-12-17 | Glycosylated steroid derivatives with anti-migratory activity |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602004011574D1 true DE602004011574D1 (de) | 2008-03-13 |
DE602004011574T2 DE602004011574T2 (de) | 2009-01-29 |
Family
ID=34702157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004011574T Expired - Fee Related DE602004011574T2 (de) | 2003-12-18 | 2004-12-17 | Glycosylierte steroidderivate mit antimigratorischer wirkung |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1709063B1 (de) |
AU (1) | AU2004299267A1 (de) |
CA (1) | CA2549074A1 (de) |
DE (1) | DE602004011574T2 (de) |
DK (1) | DK1709063T3 (de) |
ES (1) | ES2300877T3 (de) |
MX (1) | MXPA06006901A (de) |
PL (1) | PL1709063T3 (de) |
PT (1) | PT1709063E (de) |
WO (1) | WO2005058934A2 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI373473B (en) * | 2005-09-02 | 2012-10-01 | Otsuka Pharma Co Ltd | Anticancer agent |
US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
KR102055958B1 (ko) | 2011-12-22 | 2019-12-13 | 글리코미메틱스, 인크. | E-셀렉틴 길항제 화합물, 조성물, 및 이용 방법 |
CA2888527A1 (en) * | 2012-10-31 | 2014-05-08 | Glycomimetics, Inc. | E-selectin antagonists compounds and methods of use |
US9867841B2 (en) | 2012-12-07 | 2018-01-16 | Glycomimetics, Inc. | Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells |
JP6689854B2 (ja) | 2014-12-03 | 2020-04-28 | グリコミメティクス, インコーポレイテッド | E−セレクチンおよびcxcr4ケモカイン受容体のヘテロ二官能性阻害剤 |
WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
EP3497131B1 (de) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Kombination von t-zell-checkpoint-inhibitoren mit e-selectin- oder cxcr4-inhibitoren oder mit heterobifunktionellen e-selectin- wie auch cxcr4-inhibitoren |
KR102607640B1 (ko) | 2016-10-07 | 2023-11-28 | 글리코미메틱스, 인크. | 매우 강력한 다량체성 e-셀렉틴 길항물질 |
US11197877B2 (en) | 2017-03-15 | 2021-12-14 | Glycomimetics. Inc. | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists |
EP3717013A1 (de) | 2017-11-30 | 2020-10-07 | GlycoMimetics, Inc. | Verfahren zur mobilisierung von knochenmarkinfiltrierenden lymphozyten und deren verwendung |
AU2018395417B2 (en) | 2017-12-29 | 2023-07-13 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
CA3091454A1 (en) | 2018-03-05 | 2019-09-12 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0940690A (ja) * | 1995-05-23 | 1997-02-10 | Yutaka Sashita | ステロイド配糖体及びこれを有効成分とする医薬 |
JP2001002698A (ja) * | 1999-06-16 | 2001-01-09 | Kanegafuchi Chem Ind Co Ltd | 新規腫瘍細胞増殖抑制剤 |
-
2004
- 2004-12-17 DE DE602004011574T patent/DE602004011574T2/de not_active Expired - Fee Related
- 2004-12-17 EP EP04820440A patent/EP1709063B1/de active Active
- 2004-12-17 WO PCT/EP2004/014408 patent/WO2005058934A2/en active IP Right Grant
- 2004-12-17 AU AU2004299267A patent/AU2004299267A1/en not_active Abandoned
- 2004-12-17 DK DK04820440T patent/DK1709063T3/da active
- 2004-12-17 PL PL04820440T patent/PL1709063T3/pl unknown
- 2004-12-17 PT PT04820440T patent/PT1709063E/pt unknown
- 2004-12-17 MX MXPA06006901A patent/MXPA06006901A/es active IP Right Grant
- 2004-12-17 CA CA002549074A patent/CA2549074A1/en not_active Abandoned
- 2004-12-17 ES ES04820440T patent/ES2300877T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
WO2005058934A2 (en) | 2005-06-30 |
ES2300877T3 (es) | 2008-06-16 |
DK1709063T3 (da) | 2008-06-02 |
AU2004299267A1 (en) | 2005-06-30 |
EP1709063B1 (de) | 2008-01-23 |
DE602004011574T2 (de) | 2009-01-29 |
EP1709063A2 (de) | 2006-10-11 |
CA2549074A1 (en) | 2005-06-30 |
PT1709063E (pt) | 2008-04-09 |
WO2005058934A3 (en) | 2005-10-06 |
MXPA06006901A (es) | 2006-09-04 |
PL1709063T3 (pl) | 2008-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |