DE602004004124D1 - Aryl-carbaldehyd oxime-verbindungen und deren verwendung als oestrogenwirksame substanzen - Google Patents

Aryl-carbaldehyd oxime-verbindungen und deren verwendung als oestrogenwirksame substanzen

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Publication number
DE602004004124D1
DE602004004124D1 DE602004004124T DE602004004124T DE602004004124D1 DE 602004004124 D1 DE602004004124 D1 DE 602004004124D1 DE 602004004124 T DE602004004124 T DE 602004004124T DE 602004004124 T DE602004004124 T DE 602004004124T DE 602004004124 D1 DE602004004124 D1 DE 602004004124D1
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DE
Germany
Prior art keywords
aryl
active substances
oxime compounds
carbaldehyde oxime
original active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE602004004124T
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English (en)
Other versions
DE602004004124T2 (de
Inventor
Richard Eric Meushaw
Todd Cohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
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Wyeth LLC
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Publication of DE602004004124D1 publication Critical patent/DE602004004124D1/de
Application granted granted Critical
Publication of DE602004004124T2 publication Critical patent/DE602004004124T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical

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  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Anesthesiology (AREA)
DE602004004124T 2003-05-16 2004-05-13 Aryl-carbaldehyd oxime-verbindungen und deren verwendung als oestrogenwirksame substanzen Expired - Fee Related DE602004004124T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US47123803P 2003-05-16 2003-05-16
US471238P 2003-05-16
PCT/US2004/015195 WO2004103941A2 (en) 2003-05-16 2004-05-13 Aryl-carbaldehyde oxime derivatives and their use as estrogenic agents

Publications (2)

Publication Number Publication Date
DE602004004124D1 true DE602004004124D1 (de) 2007-02-15
DE602004004124T2 DE602004004124T2 (de) 2007-04-26

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Family Applications (1)

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DE602004004124T Expired - Fee Related DE602004004124T2 (de) 2003-05-16 2004-05-13 Aryl-carbaldehyd oxime-verbindungen und deren verwendung als oestrogenwirksame substanzen

Country Status (14)

Country Link
US (2) US7157491B2 (de)
EP (1) EP1633699B1 (de)
JP (1) JP2007503466A (de)
CN (1) CN100344610C (de)
AT (1) ATE350366T1 (de)
AU (1) AU2004241246A1 (de)
BR (1) BRPI0410645A (de)
CA (1) CA2525310A1 (de)
DE (1) DE602004004124T2 (de)
DK (1) DK1633699T3 (de)
ES (1) ES2277273T3 (de)
MX (1) MXPA05012249A (de)
PL (1) PL1633699T3 (de)
WO (1) WO2004103941A2 (de)

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CN100344610C (zh) 2007-10-24
WO2004103941A2 (en) 2004-12-02
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DE602004004124T2 (de) 2007-04-26
CN1791570A (zh) 2006-06-21
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US20070043077A1 (en) 2007-02-22
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