DE602004002975D1 - Porphyrin-Verbindung, deren Albumin-Einschlussverbindung und künstlicher Sauerstoffträger - Google Patents

Porphyrin-Verbindung, deren Albumin-Einschlussverbindung und künstlicher Sauerstoffträger

Info

Publication number
DE602004002975D1
DE602004002975D1 DE602004002975T DE602004002975T DE602004002975D1 DE 602004002975 D1 DE602004002975 D1 DE 602004002975D1 DE 602004002975 T DE602004002975 T DE 602004002975T DE 602004002975 T DE602004002975 T DE 602004002975T DE 602004002975 D1 DE602004002975 D1 DE 602004002975D1
Authority
DE
Germany
Prior art keywords
compound
porphyrin
oxygen carrier
albumin
artificial oxygen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004002975T
Other languages
English (en)
Other versions
DE602004002975T2 (de
Inventor
Elshun Tsuchida
Teruyuki Komatsu
Akito Nakagawa
Naomi Ohmichi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nipro Corp
Original Assignee
Nipro Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nipro Corp filed Critical Nipro Corp
Publication of DE602004002975D1 publication Critical patent/DE602004002975D1/de
Application granted granted Critical
Publication of DE602004002975T2 publication Critical patent/DE602004002975T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE602004002975T 2003-03-14 2004-03-11 Porphyrinverbindung, albumineinschlussverbindung davon und künstlicher sauerstoffträger Expired - Lifetime DE602004002975T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003069760A JP3945428B2 (ja) 2003-03-14 2003-03-14 ポルフィリン化合物、そのアルブミン包接化合物および人工酸素運搬体
JP2003069760 2003-03-14

Publications (2)

Publication Number Publication Date
DE602004002975D1 true DE602004002975D1 (de) 2006-12-14
DE602004002975T2 DE602004002975T2 (de) 2007-04-12

Family

ID=32866679

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004002975T Expired - Lifetime DE602004002975T2 (de) 2003-03-14 2004-03-11 Porphyrinverbindung, albumineinschlussverbindung davon und künstlicher sauerstoffträger

Country Status (5)

Country Link
US (3) US20040180837A1 (de)
EP (1) EP1466915B1 (de)
JP (1) JP3945428B2 (de)
AT (1) ATE344264T1 (de)
DE (1) DE602004002975T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006232818A (ja) * 2005-01-25 2006-09-07 Nipro Corp ポルフィリン金属錯体とアルブミンとの包接化合物
CN1810250A (zh) * 2005-01-25 2006-08-02 尼普洛株式会社 卟啉金属络合物与清蛋白的包合物
EP1704870A1 (de) * 2005-03-25 2006-09-27 Nipro Corporation Verwendung von Eisenverbindungen als Radiosensitizer
CN109475511A (zh) 2016-05-19 2019-03-15 高等教育联邦系统-匹兹堡大学 还原态氧载体及其用于治疗碳氧血红蛋白血症的用途
JP2019099488A (ja) * 2017-11-30 2019-06-24 小林製薬株式会社 ペプチド及びその利用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59164791A (ja) 1983-03-09 1984-09-17 Hidetoshi Tsuchida 2位に置換基を有する5,10,15,20―テトラ〔α,α,α,α―o―(ピバラミド)フェニル〕ポルフィリン化合物
JPS59162924A (ja) 1983-03-09 1984-09-13 Hidetoshi Tsuchida 酸素吸脱着剤
JP3312953B2 (ja) 1993-03-22 2002-08-12 財団法人生産開発科学研究所 2位置側鎖を有するテトラフェニルポルフィリン金属錯体及びその製造法
JP3428225B2 (ja) 1995-04-28 2003-07-22 三菱ウェルファーマ株式会社 ポルフィリン金属錯体−アルブミン包接化合物及び酸素運搬体
JP3432190B2 (ja) 1999-11-09 2003-08-04 英俊 土田 ポルフィリン金属錯体−アルブミン多量体包接化合物、及びそれを有効成分とする酸素輸液剤

Also Published As

Publication number Publication date
US7754879B2 (en) 2010-07-13
US7595394B2 (en) 2009-09-29
DE602004002975T2 (de) 2007-04-12
US20090182125A1 (en) 2009-07-16
US20060003923A1 (en) 2006-01-05
ATE344264T1 (de) 2006-11-15
EP1466915A1 (de) 2004-10-13
JP2004277329A (ja) 2004-10-07
US20040180837A1 (en) 2004-09-16
EP1466915B1 (de) 2006-11-02
JP3945428B2 (ja) 2007-07-18

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Legal Events

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8364 No opposition during term of opposition