DE60141014D1 - Verfharen zur herstellung von herpes-simplex-virus-amplikons, die resultierenden amplikons und ihre verwendung - Google Patents

Verfharen zur herstellung von herpes-simplex-virus-amplikons, die resultierenden amplikons und ihre verwendung

Info

Publication number
DE60141014D1
DE60141014D1 DE60141014T DE60141014T DE60141014D1 DE 60141014 D1 DE60141014 D1 DE 60141014D1 DE 60141014 T DE60141014 T DE 60141014T DE 60141014 T DE60141014 T DE 60141014T DE 60141014 D1 DE60141014 D1 DE 60141014D1
Authority
DE
Germany
Prior art keywords
hsv
amplicon particles
herpes simplex
simplex virus
amplicon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60141014T
Other languages
English (en)
Inventor
Howard Federoff
William Bowers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Rochester
Original Assignee
University of Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Rochester filed Critical University of Rochester
Application granted granted Critical
Publication of DE60141014D1 publication Critical patent/DE60141014D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DE60141014T 2000-05-23 2001-05-23 Verfharen zur herstellung von herpes-simplex-virus-amplikons, die resultierenden amplikons und ihre verwendung Expired - Lifetime DE60141014D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20649700P 2000-05-23 2000-05-23
PCT/US2001/016682 WO2001089304A1 (en) 2000-05-23 2001-05-23 Method of producing herpes simplex virus amplicons, resulting amplicons, and their use

Publications (1)

Publication Number Publication Date
DE60141014D1 true DE60141014D1 (de) 2010-02-25

Family

ID=22766659

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60141014T Expired - Lifetime DE60141014D1 (de) 2000-05-23 2001-05-23 Verfharen zur herstellung von herpes-simplex-virus-amplikons, die resultierenden amplikons und ihre verwendung

Country Status (7)

Country Link
EP (1) EP1289368B1 (de)
AT (1) ATE454039T1 (de)
AU (2) AU2001264862B2 (de)
CA (1) CA2410536A1 (de)
DE (1) DE60141014D1 (de)
DK (1) DK1289368T3 (de)
WO (1) WO2001089304A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE466078T1 (de) 2000-11-29 2010-05-15 Univ Rochester Helfervirus-freie herpesvirus-amplifikatpartikel und deren verwendungen
US8092791B2 (en) 2001-05-23 2012-01-10 University Of Rochester Method of producing herpes simplex virus amplicons, resulting amplicons, and their use
US20060171922A1 (en) * 2002-05-31 2006-08-03 Federoff Howard J Helper virus-free herpesvirus amplicon particles and uses thereof
US7399851B2 (en) 2002-07-25 2008-07-15 Dana Farber Cancer Institute, Inc. Composition and method for imaging cells
WO2004064765A2 (en) * 2003-01-23 2004-08-05 University Of Rochester Herpesvirus amplicon particles
EP1737493B1 (de) 2004-02-25 2011-06-29 Dana-Farber Cancer Institute, Inc. Hemmer des insulinartigen wachstumsfaktor-rezeptors-1 zur hemmung von tumorzellwachstum
US7968762B2 (en) 2004-07-13 2011-06-28 Van Andel Research Institute Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF)
EP1903873A4 (de) * 2005-06-03 2010-06-23 Univ Rochester Zusammensetzungen auf herpesvirusbasis sowie verfahren zu ihrer verwendung in der prä- und perinatalperiode
US20110039916A1 (en) * 2006-06-06 2011-02-17 University Of Rochester Helper Virus-Free Herpesvirus Amplicon Particles and Uses Thereof
JP2010510772A (ja) 2006-11-27 2010-04-08 パトリス リミテッド 新生細胞における新規なグリコシル化ペプチド標的
MX2010001307A (es) 2007-08-02 2010-07-30 Novimmune Sa Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
WO2010054221A2 (en) 2008-11-06 2010-05-14 The Johns Hopkins University Treatment of chronic inflammatory respiratory disorders
EP2258858A1 (de) 2009-06-05 2010-12-08 Universitätsklinikum Freiburg Für LSD1 transgenisches Tiermodell für Krebs
US9163240B2 (en) 2009-12-07 2015-10-20 The Johns Hopkins University SR-BI mutation as a predictor of low progesterone levels and poor fetal viability during pregnancy
EP3445773B1 (de) 2016-05-13 2022-12-28 4D Molecular Therapeutics Inc. Adeno-assoziierte virus-kapsidvarianten und verfahren zu deren verwendung
WO2019060454A2 (en) 2017-09-20 2019-03-28 4D Molecular Therapeutics Inc. CAPSID VARIANT ADENO-ASSOCIATED VIRUSES AND METHODS OF USE
SG11202004545XA (en) 2017-11-27 2020-06-29 4D Molecular Therapeutics Inc Adeno-associated virus variant capsids and use for inhibiting angiogenesis
TW202313096A (zh) 2021-05-28 2023-04-01 大陸商江蘇恆瑞醫藥股份有限公司 衣殼變異的重組腺相關病毒及其應用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2045129A1 (en) * 1989-02-01 1990-08-02 Alfred I. Geller Herpes simplex virus type i expression vector

Also Published As

Publication number Publication date
WO2001089304A1 (en) 2001-11-29
EP1289368A1 (de) 2003-03-12
EP1289368B1 (de) 2010-01-06
AU2001264862B2 (en) 2006-03-30
DK1289368T3 (da) 2010-05-03
AU6486201A (en) 2001-12-03
CA2410536A1 (en) 2001-11-29
ATE454039T1 (de) 2010-01-15
EP1289368A4 (de) 2006-04-19

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