DK1289368T3 - Fremgangsmåde til fremstilling af herpes simplex virus ampliconer, deraf resulterende amplicober samt deres anvendelse - Google Patents

Fremgangsmåde til fremstilling af herpes simplex virus ampliconer, deraf resulterende amplicober samt deres anvendelse

Info

Publication number
DK1289368T3
DK1289368T3 DK01939333.9T DK01939333T DK1289368T3 DK 1289368 T3 DK1289368 T3 DK 1289368T3 DK 01939333 T DK01939333 T DK 01939333T DK 1289368 T3 DK1289368 T3 DK 1289368T3
Authority
DK
Denmark
Prior art keywords
hsv
amplicon particles
herpes simplex
simplex virus
amplicon
Prior art date
Application number
DK01939333.9T
Other languages
English (en)
Inventor
Howard Federoff
William Bowers
Original Assignee
Univ Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rochester filed Critical Univ Rochester
Application granted granted Critical
Publication of DK1289368T3 publication Critical patent/DK1289368T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DK01939333.9T 2000-05-23 2001-05-23 Fremgangsmåde til fremstilling af herpes simplex virus ampliconer, deraf resulterende amplicober samt deres anvendelse DK1289368T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20649700P 2000-05-23 2000-05-23
PCT/US2001/016682 WO2001089304A1 (en) 2000-05-23 2001-05-23 Method of producing herpes simplex virus amplicons, resulting amplicons, and their use

Publications (1)

Publication Number Publication Date
DK1289368T3 true DK1289368T3 (da) 2010-05-03

Family

ID=22766659

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01939333.9T DK1289368T3 (da) 2000-05-23 2001-05-23 Fremgangsmåde til fremstilling af herpes simplex virus ampliconer, deraf resulterende amplicober samt deres anvendelse

Country Status (7)

Country Link
EP (1) EP1289368B1 (da)
AT (1) ATE454039T1 (da)
AU (2) AU2001264862B2 (da)
CA (1) CA2410536A1 (da)
DE (1) DE60141014D1 (da)
DK (1) DK1289368T3 (da)
WO (1) WO2001089304A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60141976D1 (de) 2000-11-29 2010-06-10 Univ Rochester Helfervirus-freie herpesvirus-amplifikatpartikel und deren verwendungen
US8092791B2 (en) 2001-05-23 2012-01-10 University Of Rochester Method of producing herpes simplex virus amplicons, resulting amplicons, and their use
US20060171922A1 (en) * 2002-05-31 2006-08-03 Federoff Howard J Helper virus-free herpesvirus amplicon particles and uses thereof
US7399851B2 (en) 2002-07-25 2008-07-15 Dana Farber Cancer Institute, Inc. Composition and method for imaging cells
AU2004206967B2 (en) * 2003-01-23 2009-10-29 University Of Rochester Herpesvirus amplicon particles
US7781393B2 (en) 2004-02-25 2010-08-24 Dana-Farber Cancer Institute, Inc. Methods for inhibiting tumor cell growth
US7968762B2 (en) 2004-07-13 2011-06-28 Van Andel Research Institute Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF)
CA2615690A1 (en) * 2005-06-03 2006-12-21 University Of Rochester Herpes virus-based compositions and methods of use in the prenatal and perinatal periods
EP2032173A4 (en) * 2006-06-06 2011-03-30 Univ Rochester HERPESVIRUS AMPLICON PARTICLES FREE OF ASSISTANT VIRUSES AND USES THEREOF
ES2476798T3 (es) 2006-11-27 2014-07-15 Patrys Limited Nueva diana de p�ptido glucosilado en células neopl�sicas
MX2010001307A (es) 2007-08-02 2010-07-30 Novimmune Sa Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos.
US9289475B2 (en) 2008-11-06 2016-03-22 The Johns Hopkins University Treatment of chronic inflammatory respiratory disorders
EP2258858A1 (en) 2009-06-05 2010-12-08 Universitätsklinikum Freiburg Transgenic LSD1 animal model for cancer
US9163240B2 (en) 2009-12-07 2015-10-20 The Johns Hopkins University SR-BI mutation as a predictor of low progesterone levels and poor fetal viability during pregnancy
CR20180589A (es) 2016-05-13 2019-02-27 4D Molecular Therapeutics Inc Cápsulas variantes de virus adenoasociados y métodos de uso de estas
BR112020005436B1 (pt) 2017-09-20 2022-08-02 4D Molecular Therapeutics Inc Proteína do capsídeo de variante do vírus adenoassociado, virion do aav recombinante (raav) infeccioso, composições, composições farmacêuticas e usos de virion de raav ou de composições farmacêuticas
CA3083472A1 (en) 2017-11-27 2019-05-31 4D Molecular Therapeutics Inc. Adeno-associated virus variant capsids and use for inhibiting angiogenesis
EP4349852A1 (en) 2021-05-28 2024-04-10 Shanghai Regenelead Therapies Co., Ltd. Recombinant adeno-associated virus having variant capsid, and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04503306A (ja) * 1989-02-01 1992-06-18 ザ・ジェネラル・ホスピタル・コーポレーション 単純ヘルペスウイルス１型発現ベクター

Also Published As

Publication number Publication date
EP1289368A4 (en) 2006-04-19
WO2001089304A1 (en) 2001-11-29
EP1289368B1 (en) 2010-01-06
AU2001264862B2 (en) 2006-03-30
ATE454039T1 (de) 2010-01-15
CA2410536A1 (en) 2001-11-29
AU6486201A (en) 2001-12-03
DE60141014D1 (de) 2010-02-25
EP1289368A1 (en) 2003-03-12

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