DE60135215D1 - Verfahren zum screening von auf zellwände wirkenden arzneistoffen - Google Patents
Verfahren zum screening von auf zellwände wirkenden arzneistoffenInfo
- Publication number
- DE60135215D1 DE60135215D1 DE60135215T DE60135215T DE60135215D1 DE 60135215 D1 DE60135215 D1 DE 60135215D1 DE 60135215 T DE60135215 T DE 60135215T DE 60135215 T DE60135215 T DE 60135215T DE 60135215 D1 DE60135215 D1 DE 60135215D1
- Authority
- DE
- Germany
- Prior art keywords
- reporter protein
- cell wall
- cell walls
- microorganism
- culture fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000002421 cell wall Anatomy 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- 238000012216 screening Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 6
- 108090000623 proteins and genes Proteins 0.000 abstract 6
- 244000005700 microbiome Species 0.000 abstract 4
- 239000012531 culture fluid Substances 0.000 abstract 3
- 210000000170 cell membrane Anatomy 0.000 abstract 2
- 102000002702 GPI-Linked Proteins Human genes 0.000 abstract 1
- 108010043685 GPI-Linked Proteins Proteins 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000132041 | 2000-05-01 | ||
| PCT/JP2001/003630 WO2001083733A1 (fr) | 2000-05-01 | 2001-04-26 | Procede de criblage de medicaments agissant sur la paroi cellulaire |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60135215D1 true DE60135215D1 (de) | 2008-09-18 |
Family
ID=18640818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60135215T Expired - Fee Related DE60135215D1 (de) | 2000-05-01 | 2001-04-26 | Verfahren zum screening von auf zellwände wirkenden arzneistoffen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20040091949A1 (de) |
| EP (1) | EP1283261B1 (de) |
| AT (1) | ATE403717T1 (de) |
| AU (1) | AU2001252604A1 (de) |
| CA (1) | CA2407906A1 (de) |
| DE (1) | DE60135215D1 (de) |
| ES (1) | ES2312425T3 (de) |
| NO (1) | NO20025217L (de) |
| WO (1) | WO2001083733A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003035898A1 (fr) * | 2001-10-22 | 2003-05-01 | Daiichi Pharmaceutical Co., Ltd. | Methode de criblage d'un medicament agissant sur la paroi cellulaire |
| JPWO2003064422A1 (ja) * | 2002-01-31 | 2005-05-26 | 第一製薬株式会社 | イミダゾ［１，２−ａ］ピリジン誘導体 |
| CN101184780B (zh) | 2005-05-05 | 2012-10-03 | 森馨香料公司 | β-葡聚糖和甘露聚糖的制备 |
| CN111679069A (zh) * | 2019-12-31 | 2020-09-18 | 安徽中医药大学 | 一种通过耳道念珠菌细胞壁重构来评价中药单体抗真菌作用的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR950702634A (ko) * | 1992-07-08 | 1995-07-29 | 이. 아디에 | 융합 단백질을 생성시킴으로써 미생물 세포의 세포벽에 효소를 고정화시키는 방법(Process for Immobilizing Enzymes to the Cell Wall of a Microbial Cell by Producing a Fusion Protein) |
| AU4566699A (en) * | 1998-06-25 | 2000-01-10 | Collaborative Group, Ltd., The | Beta(1,6)-glucan synthesis and cell wall assembly assay |
-
2001
- 2001-04-26 AT AT01925961T patent/ATE403717T1/de not_active IP Right Cessation
- 2001-04-26 ES ES01925961T patent/ES2312425T3/es not_active Expired - Lifetime
- 2001-04-26 EP EP01925961A patent/EP1283261B1/de not_active Expired - Lifetime
- 2001-04-26 WO PCT/JP2001/003630 patent/WO2001083733A1/ja active IP Right Grant
- 2001-04-26 AU AU2001252604A patent/AU2001252604A1/en not_active Abandoned
- 2001-04-26 DE DE60135215T patent/DE60135215D1/de not_active Expired - Fee Related
- 2001-04-26 US US10/258,579 patent/US20040091949A1/en not_active Abandoned
- 2001-04-26 CA CA002407906A patent/CA2407906A1/en not_active Abandoned
-
2002
- 2002-10-31 NO NO20025217A patent/NO20025217L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2312425T3 (es) | 2009-03-01 |
| NO20025217L (no) | 2002-12-30 |
| EP1283261A1 (de) | 2003-02-12 |
| AU2001252604A1 (en) | 2001-11-12 |
| WO2001083733A1 (fr) | 2001-11-08 |
| US20040091949A1 (en) | 2004-05-13 |
| NO20025217D0 (no) | 2002-10-31 |
| CA2407906A1 (en) | 2001-11-08 |
| ATE403717T1 (de) | 2008-08-15 |
| EP1283261A4 (de) | 2006-09-06 |
| EP1283261B1 (de) | 2008-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |