DE60134427D1 - Exzitatorische aminosäure-rezeptor-antagonisten - Google Patents
Exzitatorische aminosäure-rezeptor-antagonistenInfo
- Publication number
- DE60134427D1 DE60134427D1 DE60134427T DE60134427T DE60134427D1 DE 60134427 D1 DE60134427 D1 DE 60134427D1 DE 60134427 T DE60134427 T DE 60134427T DE 60134427 T DE60134427 T DE 60134427T DE 60134427 D1 DE60134427 D1 DE 60134427D1
- Authority
- DE
- Germany
- Prior art keywords
- excitative
- amino acid
- receptor antagonists
- acid receptor
- antagonists
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000015404 Amino Acid Receptors Human genes 0.000 title 1
- 108010025177 Amino Acid Receptors Proteins 0.000 title 1
- 230000002964 excitative effect Effects 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01500004 | 2001-01-05 | ||
| PCT/US2001/045857 WO2003024453A1 (en) | 2001-01-05 | 2001-12-19 | Excitatory amino acid receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60134427D1 true DE60134427D1 (de) | 2008-07-24 |
Family
ID=8183456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60134427T Expired - Lifetime DE60134427D1 (de) | 2001-01-05 | 2001-12-19 | Exzitatorische aminosäure-rezeptor-antagonisten |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP1368032B1 (enExample) |
| JP (2) | JP4132049B2 (enExample) |
| CN (1) | CN100548299C (enExample) |
| AR (1) | AR035219A1 (enExample) |
| AT (1) | ATE397931T1 (enExample) |
| AU (1) | AU2001298028B8 (enExample) |
| BR (1) | BR0116724A (enExample) |
| CA (1) | CA2432464C (enExample) |
| CY (1) | CY1108259T1 (enExample) |
| DE (1) | DE60134427D1 (enExample) |
| DK (1) | DK1368032T3 (enExample) |
| ES (1) | ES2306690T3 (enExample) |
| MX (1) | MXPA03005982A (enExample) |
| PE (1) | PE20020842A1 (enExample) |
| PT (1) | PT1368032E (enExample) |
| WO (1) | WO2003024453A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1511741E (pt) | 2002-04-26 | 2013-02-05 | Lilly Co Eli | Derivados éster de um ácido deca-hidroisoquinolino-3- carboxílico como analgésicos |
| MX2022015407A (es) | 2020-06-05 | 2023-05-16 | Noema Pharma Ag | Metodos de tratamiento del complejo de esclerosis tuberosa. |
| TWI924682B (zh) * | 2020-07-30 | 2026-05-11 | 瑞士商諾埃瑪製藥公司 | 三叉神經痛之治療方法 |
| CN116332807A (zh) * | 2023-03-24 | 2023-06-27 | 安徽秀朗新材料科技有限公司 | 一种3-（三氟甲基磺酰基）-2-萘甲酸甲酯的生产工艺 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5284957A (en) * | 1992-09-03 | 1994-02-08 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| US5446051A (en) * | 1994-05-31 | 1995-08-29 | Eli Lilly And Company | Aryl-spaced decahydroisoquinoline-3-carboxylic acids as excitatory amino acid receptor antagonists |
| TR199902449T2 (xx) * | 1997-04-07 | 2000-07-21 | Eli Lilly And Company | Farmakolojik etkin maddeler. |
| DZ3209A1 (fr) * | 1999-07-06 | 2001-01-11 | Lilly Co Eli | Antagonistes selectifs du recepteur iGLuR5 utilises dans le traitement de la migraine. |
| AU2574801A (en) * | 1999-12-22 | 2001-07-03 | Eli Lilly And Company | Selective iGLUR5 receptor antagonists |
-
2001
- 2001-12-19 CN CNB018217524A patent/CN100548299C/zh not_active Expired - Fee Related
- 2001-12-19 EP EP01274491A patent/EP1368032B1/en not_active Expired - Lifetime
- 2001-12-19 JP JP2003528549A patent/JP4132049B2/ja not_active Expired - Fee Related
- 2001-12-19 PT PT01274491T patent/PT1368032E/pt unknown
- 2001-12-19 AT AT01274491T patent/ATE397931T1/de active
- 2001-12-19 EP EP08153665A patent/EP2166003A1/en not_active Withdrawn
- 2001-12-19 AU AU2001298028A patent/AU2001298028B8/en not_active Ceased
- 2001-12-19 WO PCT/US2001/045857 patent/WO2003024453A1/en not_active Ceased
- 2001-12-19 CA CA2432464A patent/CA2432464C/en not_active Expired - Fee Related
- 2001-12-19 DK DK01274491T patent/DK1368032T3/da active
- 2001-12-19 MX MXPA03005982A patent/MXPA03005982A/es active IP Right Grant
- 2001-12-19 ES ES01274491T patent/ES2306690T3/es not_active Expired - Lifetime
- 2001-12-19 DE DE60134427T patent/DE60134427D1/de not_active Expired - Lifetime
- 2001-12-19 BR BR0116724-3A patent/BR0116724A/pt not_active IP Right Cessation
-
2002
- 2002-01-04 PE PE2002000004A patent/PE20020842A1/es not_active Application Discontinuation
- 2002-01-04 AR ARP020100031A patent/AR035219A1/es active IP Right Grant
-
2008
- 2008-03-27 JP JP2008083443A patent/JP2008179650A/ja active Pending
- 2008-08-13 CY CY20081100860T patent/CY1108259T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE20020842A1 (es) | 2002-09-21 |
| MXPA03005982A (es) | 2003-09-10 |
| CN100548299C (zh) | 2009-10-14 |
| AU2001298028B2 (en) | 2006-07-13 |
| DK1368032T3 (da) | 2008-09-29 |
| EP1368032B1 (en) | 2008-06-11 |
| CA2432464C (en) | 2011-07-19 |
| JP4132049B2 (ja) | 2008-08-13 |
| EP2166003A1 (en) | 2010-03-24 |
| ATE397931T1 (de) | 2008-07-15 |
| JP2008179650A (ja) | 2008-08-07 |
| WO2003024453A1 (en) | 2003-03-27 |
| ES2306690T3 (es) | 2008-11-16 |
| CA2432464A1 (en) | 2003-03-27 |
| BR0116724A (pt) | 2004-01-27 |
| JP2004522804A (ja) | 2004-07-29 |
| PT1368032E (pt) | 2008-09-04 |
| AU2001298028B8 (en) | 2006-08-10 |
| CN1856308A (zh) | 2006-11-01 |
| EP1368032A1 (en) | 2003-12-10 |
| AR035219A1 (es) | 2004-05-05 |
| CY1108259T1 (el) | 2014-02-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |