DE60128914D1 - Antikörper menschlichen Ursprungs zur Hemmung der Thrombozytenaggregation - Google Patents
Antikörper menschlichen Ursprungs zur Hemmung der ThrombozytenaggregationInfo
- Publication number
- DE60128914D1 DE60128914D1 DE60128914T DE60128914T DE60128914D1 DE 60128914 D1 DE60128914 D1 DE 60128914D1 DE 60128914 T DE60128914 T DE 60128914T DE 60128914 T DE60128914 T DE 60128914T DE 60128914 D1 DE60128914 D1 DE 60128914D1
- Authority
- DE
- Germany
- Prior art keywords
- human origin
- platelet aggregation
- antibodies
- inhibit platelet
- iiia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01123851A EP1300419B1 (de) | 2001-10-05 | 2001-10-05 | Antikörper menschlichen Ursprungs zur Hemmung der Thrombozytenaggregation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60128914D1 true DE60128914D1 (de) | 2007-07-26 |
DE60128914T2 DE60128914T2 (de) | 2008-05-08 |
Family
ID=8178855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60128914T Expired - Lifetime DE60128914T2 (de) | 2001-10-05 | 2001-10-05 | Antikörper menschlichen Ursprungs zur Hemmung der Thrombozytenaggregation |
Country Status (7)
Country | Link |
---|---|
US (1) | US7812136B2 (de) |
EP (1) | EP1300419B1 (de) |
JP (2) | JP4504017B2 (de) |
AT (1) | ATE364632T1 (de) |
DE (1) | DE60128914T2 (de) |
ES (1) | ES2288900T3 (de) |
WO (1) | WO2003031476A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002211658A1 (en) * | 2000-10-13 | 2002-04-22 | Uab Research Foundation | Human anti-epidermal growth factor receptor single-chain antibodies |
US8455627B2 (en) * | 2001-10-05 | 2013-06-04 | Affimed Therapeutics, Ag | Human antibody specific for activated state of platelet integrin receptor GPIIb/IIIa |
TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
US8586033B2 (en) * | 2003-12-03 | 2013-11-19 | The Scripps Research Institute | Integrin αIIbβ3 specific antibodies and peptides |
CA2613691A1 (en) * | 2005-07-05 | 2007-01-11 | Baker Medical Research Institute | Anticoagulation agent and uses thereof |
WO2007139208A1 (ja) * | 2006-05-26 | 2007-12-06 | Kurume University | 血小板の粘着凝集反応に関連する疾患の予防用又は治療用の医薬組成物、および、そのスクリーニング方法 |
US8563690B2 (en) | 2008-11-03 | 2013-10-22 | The Board Of Trustees Of The University Of Illinois | Modulation of platelet aggregation |
CA2762837C (en) | 2009-05-20 | 2021-08-03 | Novimmune S.A. | Synthetic polypeptide libraries and methods for generating naturally diversified polypeptide variants |
MX2013000301A (es) | 2010-07-09 | 2013-05-09 | Biogen Idec Hemophilia Inc | Factores quimericos de coagulacion. |
HUE049154T2 (hu) * | 2011-05-04 | 2020-09-28 | Omeros Corp | Készítmények a MASP-2-függõ komplement-aktiválás gátlására |
WO2012170969A2 (en) | 2011-06-10 | 2012-12-13 | Biogen Idec Ma Inc. | Pro-coagulant compounds and methods of use thereof |
AU2013270683A1 (en) | 2012-06-08 | 2014-12-11 | Biogen Ma Inc. | Chimeric clotting factors |
JP2015521589A (ja) | 2012-06-08 | 2015-07-30 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | プロコアグラント化合物 |
CN103483452B (zh) * | 2012-06-12 | 2021-08-13 | 上海细胞治疗集团有限公司 | 双信号独立的嵌合抗原受体及其用途 |
KR101451340B1 (ko) * | 2012-08-02 | 2014-10-15 | (주)애드바이오텍 | 모발 생장 촉진용 조성물 |
CA2899089C (en) | 2013-03-15 | 2021-10-26 | Biogen Ma Inc. | Factor ix polypeptide formulations |
EP3065769A4 (de) | 2013-11-08 | 2017-05-31 | Biogen MA Inc. | Prokoagulatorische fusionsverbindung |
CA3005158A1 (en) | 2014-11-06 | 2016-05-12 | Scholar Rock, Inc. | Anti-pro/latent-myostatin antibodies and uses thereof |
AR105654A1 (es) * | 2015-08-24 | 2017-10-25 | Lilly Co Eli | Anticuerpos pd-l1 (ligando 1 de muerte celular programada) |
JP6686768B2 (ja) * | 2015-09-03 | 2020-04-22 | 東ソー株式会社 | 細胞の分離回収方法 |
LT3350220T (lt) | 2015-09-15 | 2021-09-27 | Scholar Rock, Inc. | Anti pro/latentinio miostatino antikūnai ir jų panaudojimas |
CN109071645A (zh) | 2016-01-08 | 2018-12-21 | 供石公司 | 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法 |
KR102271635B1 (ko) | 2016-06-13 | 2021-07-06 | 스칼러 락, 인크. | 미오스타틴 억제제의 용도 및 조합 요법 |
FI3565592T3 (fi) | 2017-01-06 | 2023-05-10 | Scholar Rock Inc | Metabolisten tautien hoitaminen estämällä myostatiinin aktivaatio |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2776634B2 (ja) * | 1991-09-17 | 1998-07-16 | 帝人株式会社 | グリコプロテイン ▲II▼b/▲III▼aに対するヒト型モノクローナル抗体 |
AU6235294A (en) * | 1993-02-02 | 1994-08-29 | Scripps Research Institute, The | Methods for producing polypeptide binding sites |
US6265150B1 (en) * | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
EP0990034A1 (de) * | 1997-06-06 | 2000-04-05 | Asat AG Applied Science & Technology | Anti-gpiib/iiia rekombinante antikörper |
CA2361877A1 (en) * | 1999-03-01 | 2000-09-08 | Genentech, Inc. | Antibodies for cancer therapy and diagnosis |
-
2001
- 2001-10-05 ES ES01123851T patent/ES2288900T3/es not_active Expired - Lifetime
- 2001-10-05 DE DE60128914T patent/DE60128914T2/de not_active Expired - Lifetime
- 2001-10-05 EP EP01123851A patent/EP1300419B1/de not_active Expired - Lifetime
- 2001-10-05 AT AT01123851T patent/ATE364632T1/de active
-
2002
- 2002-10-04 JP JP2003534458A patent/JP4504017B2/ja not_active Expired - Lifetime
- 2002-10-04 WO PCT/EP2002/011154 patent/WO2003031476A1/en active Application Filing
- 2002-10-04 US US10/491,766 patent/US7812136B2/en active Active
-
2009
- 2009-10-29 JP JP2009248999A patent/JP2010029203A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE60128914T2 (de) | 2008-05-08 |
ES2288900T3 (es) | 2008-02-01 |
JP2005514009A (ja) | 2005-05-19 |
EP1300419B1 (de) | 2007-06-13 |
EP1300419A1 (de) | 2003-04-09 |
JP2010029203A (ja) | 2010-02-12 |
JP4504017B2 (ja) | 2010-07-14 |
US20070218067A1 (en) | 2007-09-20 |
ATE364632T1 (de) | 2007-07-15 |
US7812136B2 (en) | 2010-10-12 |
WO2003031476A1 (en) | 2003-04-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |