DE60125056D1 - Homogener biochemischer durchflusstest, beruhend auf dem massenspektrometrischen nachweis bekannter ligandmoleküle - Google Patents

Homogener biochemischer durchflusstest, beruhend auf dem massenspektrometrischen nachweis bekannter ligandmoleküle

Info

Publication number
DE60125056D1
DE60125056D1 DE60125056T DE60125056T DE60125056D1 DE 60125056 D1 DE60125056 D1 DE 60125056D1 DE 60125056 T DE60125056 T DE 60125056T DE 60125056 T DE60125056 T DE 60125056T DE 60125056 D1 DE60125056 D1 DE 60125056D1
Authority
DE
Germany
Prior art keywords
present
mass spectrometric
test based
flow test
known ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60125056T
Other languages
English (en)
Other versions
DE60125056T2 (de
Inventor
Hubertus Irth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kiadis BV
Original Assignee
Kiadis BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kiadis BV filed Critical Kiadis BV
Publication of DE60125056D1 publication Critical patent/DE60125056D1/de
Application granted granted Critical
Publication of DE60125056T2 publication Critical patent/DE60125056T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60125056T 2000-10-30 2001-10-30 Homogener biochemischer durchflusstest, beruhend auf dem massenspektrometrischen nachweis bekannter ligandmoleküle Expired - Lifetime DE60125056T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00203776 2000-10-30
EP00203776A EP1202056A1 (de) 2000-10-30 2000-10-30 Homogener biochemischer Durchflusstest, beruhend auf dem massenspektrometrischen Nachweis bekannter Ligandmoleküle
PCT/NL2001/000794 WO2002037111A2 (en) 2000-10-30 2001-10-30 Continuous-flow homogeneous biochemical assays based on mass spectrometric detection of known ligands

Publications (2)

Publication Number Publication Date
DE60125056D1 true DE60125056D1 (de) 2007-01-18
DE60125056T2 DE60125056T2 (de) 2007-07-05

Family

ID=8172196

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60125056T Expired - Lifetime DE60125056T2 (de) 2000-10-30 2001-10-30 Homogener biochemischer durchflusstest, beruhend auf dem massenspektrometrischen nachweis bekannter ligandmoleküle

Country Status (7)

Country Link
US (1) US20040053424A1 (de)
EP (2) EP1202056A1 (de)
JP (1) JP2004513345A (de)
AT (1) ATE347694T1 (de)
AU (1) AU2002224201A1 (de)
DE (1) DE60125056T2 (de)
WO (1) WO2002037111A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10125258A1 (de) * 2001-05-23 2003-01-09 November Ag Molekulare Medizin Verfahren zur Bestimmung des Bindeverhaltens von an Ziel-Molekülen spezifisch bindenden Liganden
EP1367133A1 (de) * 2002-05-31 2003-12-03 Kiadis B.V. Durchfluss Enzymassay mit einem massenspektrometrischen Nachweis
CN103038631A (zh) * 2010-03-10 2013-04-10 珀菲尼迪生物科学股份有限公司 用于在单次分析中识别多种分析物并对其进行定量的方法
CN117126938A (zh) * 2023-10-08 2023-11-28 常州市第一人民医院 一种用于诊断膜性肾病的生物标志物及其应用方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2101595A1 (de) * 1971-01-14 1972-07-27 CH. Boehringer Sohn, 6507 Ingelheim Neue Acylderivate des Digoxins und Verfahren zu deren Herstellung
US3997298A (en) * 1975-02-27 1976-12-14 Cornell Research Foundation, Inc. Liquid chromatography-mass spectrometry system and method
AU2407192A (en) * 1991-08-01 1993-03-02 Pharmaceutical Discovery Corporation Characterization of specific drug receptors with fluorescent ligands
US5326778A (en) * 1992-03-03 1994-07-05 Research Corporation Technologies, Inc. Conjugates of biotin and deferoxamine for radioimmunoimaging and radioimmunotherapy
AU2369895A (en) * 1994-04-29 1995-11-29 Perseptive Biosystems, Inc. Activated esters of 1-phenylpyrazolin-5-one for labelling amine-functionalized molecules
GB9510830D0 (en) * 1995-05-27 1995-07-19 Zeneca Ltd Proteins
EP0795327A1 (de) * 1996-03-13 1997-09-17 Pfizer Inc. Verwendung von Amlodipin zur Behandlung von Prophylaxe von kongestivem Herzversagen nichtischämischen Ursprungs
CA2293593A1 (en) * 1997-06-03 1998-12-10 Arqule, Inc. An automated, high throughput method for screening a plurality of compounds using mass spectrometry
US20030096232A1 (en) * 1997-12-19 2003-05-22 Kris Richard M. High throughput assay system
US6428956B1 (en) * 1998-03-02 2002-08-06 Isis Pharmaceuticals, Inc. Mass spectrometric methods for biomolecular screening
US6191418B1 (en) * 1998-03-27 2001-02-20 Synsorb Biotech, Inc. Device for delivery of multiple liquid sample streams to a mass spectrometer
US6770486B1 (en) * 2000-02-08 2004-08-03 Isis Pharmaceuticals, Inc. Optimization of ligand affinity for RNA targets using mass spectrometry
WO2002034933A2 (en) * 2000-10-20 2002-05-02 Igen International, Inc. Methods and compositions for modifying biologically active target molecules

Also Published As

Publication number Publication date
EP1202056A1 (de) 2002-05-02
DE60125056T2 (de) 2007-07-05
WO2002037111A3 (en) 2002-08-08
EP1330648A2 (de) 2003-07-30
US20040053424A1 (en) 2004-03-18
EP1330648B1 (de) 2006-12-06
ATE347694T1 (de) 2006-12-15
WO2002037111A2 (en) 2002-05-10
AU2002224201A1 (en) 2002-05-15
JP2004513345A (ja) 2004-04-30

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Legal Events

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