DE60123934D1 - Das parkin-protein als ubiquitinligase - Google Patents

Das parkin-protein als ubiquitinligase

Info

Publication number
DE60123934D1
DE60123934D1 DE60123934T DE60123934T DE60123934D1 DE 60123934 D1 DE60123934 D1 DE 60123934D1 DE 60123934 T DE60123934 T DE 60123934T DE 60123934 T DE60123934 T DE 60123934T DE 60123934 D1 DE60123934 D1 DE 60123934D1
Authority
DE
Germany
Prior art keywords
ubiquitinligase
parkin protein
parkin
protein
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60123934T
Other languages
English (en)
Other versions
DE60123934T2 (de
Inventor
Yoshikuni Mizuno
Nobuyoshi Shimizu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Application granted granted Critical
Publication of DE60123934D1 publication Critical patent/DE60123934D1/de
Publication of DE60123934T2 publication Critical patent/DE60123934T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Noodles (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Image Processing (AREA)
DE60123934T 2000-02-24 2001-02-26 Das parkin-protein als ubiquitinligase Expired - Fee Related DE60123934T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000047801 2000-02-24
JP2000047801 2000-02-24
PCT/JP2001/001399 WO2001062957A1 (fr) 2000-02-24 2001-02-26 Proteine parkine utilisee comme ubiquitine ligase

Publications (2)

Publication Number Publication Date
DE60123934D1 true DE60123934D1 (de) 2006-11-30
DE60123934T2 DE60123934T2 (de) 2007-10-18

Family

ID=18569991

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60123934T Expired - Fee Related DE60123934T2 (de) 2000-02-24 2001-02-26 Das parkin-protein als ubiquitinligase

Country Status (10)

Country Link
US (1) US20050042607A1 (de)
EP (1) EP1262557B1 (de)
AT (1) ATE343001T1 (de)
AU (1) AU2001234171A1 (de)
CA (1) CA2398703A1 (de)
DE (1) DE60123934T2 (de)
DK (1) DK1262557T3 (de)
ES (1) ES2272444T3 (de)
MX (1) MXPA02008256A (de)
WO (1) WO2001062957A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1969367B1 (de) * 2005-12-12 2011-08-10 Elan Pharmaceuticals Inc. Test für morbus-parkinson-therapeutika
US8017348B1 (en) * 2005-12-12 2011-09-13 Elan Pharma International Limited Assay for Parkinson's Disease therapeutics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE315645T1 (de) * 1998-02-09 2006-02-15 Boehringer Ingelheim Int Dns oder gene, die an der parkinsonschen krankheit beteiligt sind
GB9826276D0 (en) * 1998-12-01 1999-01-20 Univ Leeds Therapeutic agents for use in degenerative disorders
US7070940B2 (en) * 2002-07-18 2006-07-04 Aventis Pharma S.A. Method for determining the ability of a compound to modify the interaction between parkin and the p38 protein

Also Published As

Publication number Publication date
EP1262557B1 (de) 2006-10-18
AU2001234171A1 (en) 2001-09-03
US20050042607A1 (en) 2005-02-24
ATE343001T1 (de) 2006-11-15
CA2398703A1 (en) 2001-08-30
EP1262557A1 (de) 2002-12-04
WO2001062957A1 (fr) 2001-08-30
ES2272444T3 (es) 2007-05-01
DE60123934T2 (de) 2007-10-18
DK1262557T3 (da) 2006-11-13
EP1262557A4 (de) 2003-05-02
MXPA02008256A (es) 2003-01-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee