DE60120712T2 - Kallikrein gen - Google Patents
Kallikrein gen Download PDFInfo
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- DE60120712T2 DE60120712T2 DE60120712T DE60120712T DE60120712T2 DE 60120712 T2 DE60120712 T2 DE 60120712T2 DE 60120712 T DE60120712 T DE 60120712T DE 60120712 T DE60120712 T DE 60120712T DE 60120712 T2 DE60120712 T2 DE 60120712T2
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- klk15
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21034—Plasma kallikrein (3.4.21.34)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
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- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22485300P | 2000-08-11 | 2000-08-11 | |
| US224853P | 2000-08-11 | ||
| PCT/CA2001/001141 WO2002014485A2 (en) | 2000-08-11 | 2001-08-10 | Kallikrein gene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60120712D1 DE60120712D1 (en) | 2006-07-27 |
| DE60120712T2 true DE60120712T2 (de) | 2007-07-19 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60120712T Expired - Lifetime DE60120712T2 (de) | 2000-08-11 | 2001-08-10 | Kallikrein gen |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7199229B2 (enExample) |
| EP (1) | EP1309703B1 (enExample) |
| JP (1) | JP2004505649A (enExample) |
| AT (1) | ATE330017T1 (enExample) |
| AU (2) | AU2001287384B2 (enExample) |
| CA (1) | CA2418422C (enExample) |
| DE (1) | DE60120712T2 (enExample) |
| ES (1) | ES2266245T3 (enExample) |
| WO (1) | WO2002014485A2 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| US9012141B2 (en) * | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| DE60120712T2 (de) | 2000-08-11 | 2007-07-19 | Mount Sinai Hospital, Toronto | Kallikrein gen |
| EP1330652B1 (en) * | 2000-10-27 | 2007-06-27 | Mount Sinai Hospital | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
| US7741019B2 (en) | 2000-11-01 | 2010-06-22 | Mount Sinai Hospital | Detection of ovarian cancer |
| WO2002097438A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| WO2003033731A2 (en) * | 2001-10-16 | 2003-04-24 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| US20060159616A1 (en) * | 2002-08-28 | 2006-07-20 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| CA2497058A1 (en) * | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| WO2004029285A2 (en) * | 2002-09-26 | 2004-04-08 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| WO2004075713A2 (en) * | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| US20060141471A1 (en) * | 2003-02-27 | 2006-06-29 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| CA2468651A1 (en) * | 2003-06-13 | 2004-12-13 | Eleftherios P. Diamandis | Detection of neurodegenerative diseases |
| US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
| EP1711616A1 (en) * | 2004-01-28 | 2006-10-18 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with kallikrein 15 (klk15) |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| ES2741730T3 (es) | 2008-05-19 | 2020-02-12 | Advaxis Inc | Sistema de administración doble para antígenos heterólogos que comprende una cepa de Listeria recombinante atenuada por la mutación de dal/dat y la deleción de ActA que comprende una molécula de ácido nucleico que codifica una proteína de fusión de listeriolisina O - antígeno prostático específico |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| WO2012138377A2 (en) | 2010-10-01 | 2012-10-11 | Trustees Of The University Of Pennsylvania | The use of listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals |
| WO2012125551A1 (en) | 2011-03-11 | 2012-09-20 | Advaxis | Listeria-based adjuvants |
| EP2825195A4 (en) | 2012-03-12 | 2015-10-07 | Advaxis Inc | INHIBITION OF SUPPRESSOR CELL FUNCTION AFTER TREATMENT WITH A LISTERIAL VACCINE |
| GB201513921D0 (en) * | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022497B1 (en) | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| JP2004501637A (ja) * | 2000-06-26 | 2004-01-22 | スージェン・インコーポレーテッド | 新規プロテアーゼ |
| JP2004515220A (ja) * | 2000-07-21 | 2004-05-27 | インサイト・ゲノミックス・インコーポレイテッド | プロテアーゼ |
| DE60120712T2 (de) * | 2000-08-11 | 2007-07-19 | Mount Sinai Hospital, Toronto | Kallikrein gen |
| US6962793B2 (en) * | 2000-10-27 | 2005-11-08 | Mount Sinai Hospital | Methods for detecting Alzheimers disease |
| EP1330652B1 (en) * | 2000-10-27 | 2007-06-27 | Mount Sinai Hospital | Method for detecting ovarian cancer based on human kallikrein 6 (hk6) |
| US7741019B2 (en) * | 2000-11-01 | 2010-06-22 | Mount Sinai Hospital | Detection of ovarian cancer |
| WO2002097438A1 (en) * | 2001-05-25 | 2002-12-05 | Mount Sinai Hospital | Method of detecting and monitoring prostate and ovarian cancers |
| WO2003033731A2 (en) * | 2001-10-16 | 2003-04-24 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| AU2003213960A1 (en) | 2002-04-04 | 2003-10-20 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| CA2497058A1 (en) | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| US20060159616A1 (en) | 2002-08-28 | 2006-07-20 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| WO2004029285A2 (en) | 2002-09-26 | 2004-04-08 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| WO2004075713A2 (en) | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| US20060141471A1 (en) | 2003-02-27 | 2006-06-29 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| CA2468651A1 (en) | 2003-06-13 | 2004-12-13 | Eleftherios P. Diamandis | Detection of neurodegenerative diseases |
| US20060269971A1 (en) | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
-
2001
- 2001-08-10 DE DE60120712T patent/DE60120712T2/de not_active Expired - Lifetime
- 2001-08-10 AU AU2001287384A patent/AU2001287384B2/en not_active Ceased
- 2001-08-10 AT AT01966837T patent/ATE330017T1/de not_active IP Right Cessation
- 2001-08-10 AU AU8738401A patent/AU8738401A/xx active Pending
- 2001-08-10 EP EP01966837A patent/EP1309703B1/en not_active Expired - Lifetime
- 2001-08-10 JP JP2002519613A patent/JP2004505649A/ja active Pending
- 2001-08-10 US US10/344,394 patent/US7199229B2/en not_active Expired - Fee Related
- 2001-08-10 ES ES01966837T patent/ES2266245T3/es not_active Expired - Lifetime
- 2001-08-10 WO PCT/CA2001/001141 patent/WO2002014485A2/en not_active Ceased
- 2001-08-10 CA CA2418422A patent/CA2418422C/en not_active Expired - Fee Related
-
2007
- 2007-03-29 US US11/729,560 patent/US7507403B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20040058342A1 (en) | 2004-03-25 |
| CA2418422C (en) | 2011-06-07 |
| WO2002014485A2 (en) | 2002-02-21 |
| ATE330017T1 (de) | 2006-07-15 |
| AU2001287384B2 (en) | 2007-03-29 |
| WO2002014485A3 (en) | 2003-01-09 |
| ES2266245T3 (es) | 2007-03-01 |
| JP2004505649A (ja) | 2004-02-26 |
| CA2418422A1 (en) | 2002-02-21 |
| US7199229B2 (en) | 2007-04-03 |
| DE60120712D1 (en) | 2006-07-27 |
| US7507403B2 (en) | 2009-03-24 |
| US20070178114A1 (en) | 2007-08-02 |
| EP1309703B1 (en) | 2006-06-14 |
| AU8738401A (en) | 2002-02-25 |
| EP1309703A2 (en) | 2003-05-14 |
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| 8364 | No opposition during term of opposition |