DE60113689D1 - 2-aminothiazolinderivate und ihre verwendung als no-synthase inhibitoren - Google Patents
2-aminothiazolinderivate und ihre verwendung als no-synthase inhibitorenInfo
- Publication number
- DE60113689D1 DE60113689D1 DE60113689T DE60113689T DE60113689D1 DE 60113689 D1 DE60113689 D1 DE 60113689D1 DE 60113689 T DE60113689 T DE 60113689T DE 60113689 T DE60113689 T DE 60113689T DE 60113689 D1 DE60113689 D1 DE 60113689D1
- Authority
- DE
- Germany
- Prior art keywords
- synthase inhibitors
- aminothiazoline
- derivatives
- aminothiazoline derivatives
- synthase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0007397A FR2810037B1 (fr) | 2000-06-09 | 2000-06-09 | Utilisation de derives de 2-aminothiazoline comme inhibiteurs de no-synthase inductible |
FR0007397 | 2000-06-09 | ||
PCT/FR2001/001760 WO2001094325A1 (fr) | 2000-06-09 | 2001-06-07 | Derives de 2-aminothiazoline et leur utilisation comme inhibiteurs de no-synthase |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60113689D1 true DE60113689D1 (de) | 2006-02-09 |
DE60113689T2 DE60113689T2 (de) | 2006-07-13 |
Family
ID=8851134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60113689T Expired - Lifetime DE60113689T2 (de) | 2000-06-09 | 2001-06-07 | 2-aminothiazolinderivate und ihre verwendung als no-synthase inhibitoren |
Country Status (29)
Country | Link |
---|---|
EP (1) | EP1299365B1 (de) |
JP (1) | JP4238026B2 (de) |
KR (1) | KR20030025931A (de) |
CN (1) | CN1202096C (de) |
AP (1) | AP2002002708A0 (de) |
AR (1) | AR029937A1 (de) |
AT (1) | ATE305460T1 (de) |
AU (1) | AU2001266124A1 (de) |
BR (1) | BR0111986A (de) |
CA (1) | CA2411760C (de) |
DE (1) | DE60113689T2 (de) |
DK (1) | DK1299365T3 (de) |
DZ (1) | DZ3367A1 (de) |
EA (1) | EA200300010A1 (de) |
EC (1) | ECSP024375A (de) |
ES (1) | ES2248347T3 (de) |
FR (1) | FR2810037B1 (de) |
HK (1) | HK1057900A1 (de) |
HR (1) | HRP20020970A2 (de) |
HU (1) | HUP0301000A2 (de) |
IL (1) | IL153328A0 (de) |
MA (1) | MA25814A1 (de) |
MX (1) | MXPA02012071A (de) |
NO (1) | NO20025884L (de) |
NZ (1) | NZ522968A (de) |
OA (1) | OA12286A (de) |
PL (1) | PL360285A1 (de) |
WO (1) | WO2001094325A1 (de) |
ZA (1) | ZA200209769B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2461801A1 (en) * | 2001-09-26 | 2003-04-03 | Yissum Research Development Company Of The Hebrew University Of Jerusale M | Sphingolipids |
JP2005526005A (ja) * | 2001-11-09 | 2005-09-02 | アベンティス・ファーマ・ソシエテ・アノニム | 誘導型noシンターゼの阻害剤としての2−アミノ−チアゾリン誘導体及びその使用 |
PL370267A1 (en) * | 2001-11-09 | 2005-05-16 | Aventis Pharma S.A. | Use of 2-amino-4-pyridylmethyl-thiazoline derivatives as inhibitors of inducible no-synthase |
MXPA04003766A (es) * | 2001-11-09 | 2004-07-29 | Aventis Pharma Sa | Derivados de 2-amino-4-heteroariletil tiazolina y su utilizacion como inhibidores de no sintasa inducible. |
AU2002238889A1 (en) * | 2002-03-14 | 2003-09-22 | Dainippon Pharmaceutical Co., Ltd. | Nitrogen monoxide synthase inhibitors |
ES2295672T3 (es) * | 2002-08-07 | 2008-04-16 | Neuraxon Inc. | Compuestos de aminobenzotiazol con actividad inhibitoria de la oxido nitrico sintasa (nos). |
DE10332560B4 (de) * | 2003-07-11 | 2010-07-08 | Chiracon Gmbh | Verfahren zur Herstellung von ß- Heteroaryl-2-alanin-Verbindungen über 2-Amino-2-(heteroarylmethyl)-carbonsäure-Verbindungen |
KR101800507B1 (ko) | 2015-09-18 | 2018-01-18 | 주식회사 이엔이티아이 | 자동세척 스크린과 식물정화장치를 활용하여 지속적으로 유입되는 생활하수나 공정폐수가 유입되는 오염하천정화를 위한 방법 및 그 장치 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5066662A (en) * | 1990-05-21 | 1991-11-19 | Warner-Lambert Company | Substituted oxazolidin-2-ones and 1,2,4-oxadiazolin-5-ones and derivatives thereof acting at muscarinic receptors |
AU5533094A (en) * | 1992-11-27 | 1994-06-22 | Wellcome Foundation Limited, The | Enzyme inhibitors |
EP0724570B1 (de) * | 1993-10-21 | 1999-03-03 | G.D. Searle & Co. | Amidino-derivate als no-synthetase inhibitoren |
AU4149696A (en) * | 1994-11-15 | 1996-06-06 | Merck & Co., Inc. | Substituted heterocycles as inhibitors of nitric oxide synthase |
AU2223501A (en) * | 1999-12-24 | 2001-07-09 | Kyowa Hakko Kogyo Co. Ltd. | Fused purine derivatives |
-
2000
- 2000-06-09 FR FR0007397A patent/FR2810037B1/fr not_active Expired - Fee Related
-
2001
- 2001-06-07 EA EA200300010A patent/EA200300010A1/ru unknown
- 2001-06-07 DE DE60113689T patent/DE60113689T2/de not_active Expired - Lifetime
- 2001-06-07 MX MXPA02012071A patent/MXPA02012071A/es active IP Right Grant
- 2001-06-07 AP APAP/P/2002/002708A patent/AP2002002708A0/en unknown
- 2001-06-07 IL IL15332801A patent/IL153328A0/xx unknown
- 2001-06-07 CA CA002411760A patent/CA2411760C/fr not_active Expired - Fee Related
- 2001-06-07 DK DK01943580T patent/DK1299365T3/da active
- 2001-06-07 JP JP2002501875A patent/JP4238026B2/ja not_active Expired - Fee Related
- 2001-06-07 AU AU2001266124A patent/AU2001266124A1/en not_active Abandoned
- 2001-06-07 WO PCT/FR2001/001760 patent/WO2001094325A1/fr active IP Right Grant
- 2001-06-07 KR KR1020027016766A patent/KR20030025931A/ko not_active Application Discontinuation
- 2001-06-07 OA OA1200200372A patent/OA12286A/fr unknown
- 2001-06-07 NZ NZ522968A patent/NZ522968A/en unknown
- 2001-06-07 BR BR0111986-9A patent/BR0111986A/pt not_active Application Discontinuation
- 2001-06-07 DZ DZ013367A patent/DZ3367A1/xx active
- 2001-06-07 EP EP01943580A patent/EP1299365B1/de not_active Expired - Lifetime
- 2001-06-07 PL PL36028501A patent/PL360285A1/xx unknown
- 2001-06-07 AT AT01943580T patent/ATE305460T1/de not_active IP Right Cessation
- 2001-06-07 CN CNB01813386XA patent/CN1202096C/zh not_active Expired - Fee Related
- 2001-06-07 AR ARP010102730A patent/AR029937A1/es not_active Application Discontinuation
- 2001-06-07 ES ES01943580T patent/ES2248347T3/es not_active Expired - Lifetime
- 2001-06-07 HU HU0301000A patent/HUP0301000A2/hu unknown
-
2002
- 2002-12-02 ZA ZA200209769A patent/ZA200209769B/en unknown
- 2002-12-06 HR HR20020970A patent/HRP20020970A2/xx not_active Application Discontinuation
- 2002-12-06 NO NO20025884A patent/NO20025884L/no not_active Application Discontinuation
- 2002-12-09 MA MA26939A patent/MA25814A1/fr unknown
- 2002-12-09 EC EC2002004375A patent/ECSP024375A/es unknown
-
2004
- 2004-02-06 HK HK04100771A patent/HK1057900A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC |