DE60111774D1 - Antibakterielle verbindungen - Google Patents

Antibakterielle verbindungen

Info

Publication number
DE60111774D1
DE60111774D1 DE60111774T DE60111774T DE60111774D1 DE 60111774 D1 DE60111774 D1 DE 60111774D1 DE 60111774 T DE60111774 T DE 60111774T DE 60111774 T DE60111774 T DE 60111774T DE 60111774 D1 DE60111774 D1 DE 60111774D1
Authority
DE
Germany
Prior art keywords
sub
alkyl
sup
antibacterial compounds
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60111774T
Other languages
English (en)
Other versions
DE60111774T2 (de
Inventor
A Seefeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of DE60111774D1 publication Critical patent/DE60111774D1/de
Publication of DE60111774T2 publication Critical patent/DE60111774T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60111774T 2000-12-08 2001-12-07 Antibakterielle verbindungen Expired - Fee Related DE60111774T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25427600P 2000-12-08 2000-12-08
US254276P 2000-12-08
PCT/US2001/048104 WO2002062339A1 (en) 2000-12-08 2001-12-07 Antibacterial compounds

Publications (2)

Publication Number Publication Date
DE60111774D1 true DE60111774D1 (de) 2005-08-04
DE60111774T2 DE60111774T2 (de) 2006-05-04

Family

ID=22963638

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60111774T Expired - Fee Related DE60111774T2 (de) 2000-12-08 2001-12-07 Antibakterielle verbindungen

Country Status (7)

Country Link
US (1) US6987115B2 (de)
EP (1) EP1347759B1 (de)
JP (1) JP2004532816A (de)
AT (1) ATE298570T1 (de)
DE (1) DE60111774T2 (de)
ES (1) ES2241902T3 (de)
WO (1) WO2002062339A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60112974T2 (de) 2001-02-12 2006-02-16 Lilly Icos Llc, Wilmington Carbolinderivate
DE60216233T2 (de) * 2001-02-12 2007-09-27 Lilly Icos Llc, Wilmington Carbolinderivate
ATE414082T1 (de) * 2003-04-29 2008-11-15 Oscient Pharmaceuticals Antibiotische tetrahydro-b-carbolinderivative
CN102408425A (zh) * 2004-03-15 2012-04-11 Ptc医疗公司 用于抑制血管生成的咔啉衍生物及其应用
US7364432B2 (en) * 2004-03-31 2008-04-29 Drb Lit Ltd. Methods of selecting Lock-In Training courses and sessions
EP1783128A1 (de) * 2005-11-07 2007-05-09 Eidgenössische Technische Hochschule Zürich Heterozyklische Verbindungen und deren Anwendung als Antifouling-Mittel
CA2707442A1 (en) * 2007-11-30 2009-08-20 Biota Scientific Management Pty Ltd Antibiotic tetrahydro-beta-carboline derivatives
EP2225250A2 (de) 2007-11-30 2010-09-08 Biota Scientific Management Pty Ltd Bicyclische ppat-inhibitoren als antibakterielle mittel
SG176260A1 (en) 2009-05-27 2012-01-30 Ptc Therapeutics Inc Processes for the preparation of substituted tetrahydro beta-carbolines
US8697662B2 (en) 2009-05-27 2014-04-15 Ptc Therapeutics, Inc. Methods for treating Kaposi sarcoma
US8703726B2 (en) 2009-05-27 2014-04-22 Ptc Therapeutics, Inc. Methods for treating prostate conditions
EP3718405A1 (de) 2009-05-27 2020-10-07 PTC Therapeutics, Inc. Verfahren zur behandlung von krebs und nichtneoplastischen leiden
MY198354A (en) 2014-12-18 2023-08-28 Hoffmann La Roche Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof
US20180002344A1 (en) 2016-06-16 2018-01-04 Genentech, Inc. Heteroaryl estrogen receptor modulators and uses thereof
US11458126B2 (en) 2017-08-01 2022-10-04 Ptc Therapeutics, Inc. DHODH inhibitor for use in treating hematologic cancers
HUE064542T2 (hu) 2018-06-21 2024-03-28 Hoffmann La Roche A 3-((1R,3R)1(2,6-difluoro-4-((1-(3-fluoropropil)azetidin-3-il)amino)fenil)-3-metil-1,3,4,9 -tetrahidro-2H-pirido[3,4-b]indol-2-il)-2,2-difluoropropán-1-ol tartarátsó szilárd formái, eljárás elõállításukra és rákos megbetegedések kezelésében történõ alkalmazási módszereik
EP3836919A4 (de) * 2018-08-16 2022-05-18 Recreo Pharmaceuticals Inc. 1,3,4,9-tetrahydro-2h-pyrido[3,4-b]indol-derivatverbindungen und verwendungen davon

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR024158A1 (es) * 1999-06-01 2002-09-04 Smithkline Beecham Corp Compuestos antibacterianos
UA74826C2 (en) 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors

Also Published As

Publication number Publication date
ES2241902T3 (es) 2005-11-01
US20040053954A1 (en) 2004-03-18
DE60111774T2 (de) 2006-05-04
EP1347759B1 (de) 2005-06-29
EP1347759A4 (de) 2004-04-21
JP2004532816A (ja) 2004-10-28
ATE298570T1 (de) 2005-07-15
EP1347759A1 (de) 2003-10-01
US6987115B2 (en) 2006-01-17
WO2002062339A1 (en) 2002-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee