ATE298570T1 - Antibakterielle verbindungen - Google Patents

Antibakterielle verbindungen

Info

Publication number
ATE298570T1
ATE298570T1 AT01998040T AT01998040T ATE298570T1 AT E298570 T1 ATE298570 T1 AT E298570T1 AT 01998040 T AT01998040 T AT 01998040T AT 01998040 T AT01998040 T AT 01998040T AT E298570 T1 ATE298570 T1 AT E298570T1
Authority
AT
Austria
Prior art keywords
sub
alkyl
sup
antibacterial compounds
compounds
Prior art date
Application number
AT01998040T
Other languages
English (en)
Inventor
Mark A Seefeld
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE298570T1 publication Critical patent/ATE298570T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT01998040T 2000-12-08 2001-12-07 Antibakterielle verbindungen ATE298570T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25427600P 2000-12-08 2000-12-08
PCT/US2001/048104 WO2002062339A1 (en) 2000-12-08 2001-12-07 Antibacterial compounds

Publications (1)

Publication Number Publication Date
ATE298570T1 true ATE298570T1 (de) 2005-07-15

Family

ID=22963638

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01998040T ATE298570T1 (de) 2000-12-08 2001-12-07 Antibakterielle verbindungen

Country Status (7)

Country Link
US (1) US6987115B2 (de)
EP (1) EP1347759B1 (de)
JP (1) JP2004532816A (de)
AT (1) ATE298570T1 (de)
DE (1) DE60111774T2 (de)
ES (1) ES2241902T3 (de)
WO (1) WO2002062339A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2272695T3 (es) * 2001-02-12 2007-05-01 Lilly Icos Llc Derivados de carbolina.
AU2002246728A1 (en) * 2001-02-12 2002-08-28 Lilly Icos Llc Carboline derivatives
WO2004096802A2 (en) * 2003-04-29 2004-11-11 Oscient Pharmaceuticals ANTIBIOTIC TETRAHYDRO-β-CARBOLINE DERIVATIVES
EA201200555A1 (ru) * 2004-03-15 2013-01-30 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Производные карболина, полезные в ингибировании ангиогенеза
US7364432B2 (en) * 2004-03-31 2008-04-29 Drb Lit Ltd. Methods of selecting Lock-In Training courses and sessions
EP1783128A1 (de) * 2005-11-07 2007-05-09 Eidgenössische Technische Hochschule Zürich Heterozyklische Verbindungen und deren Anwendung als Antifouling-Mittel
CN102007130A (zh) * 2007-11-30 2011-04-06 生物区科学管理控股有限公司 抗生素四氢-β-咔啉衍生物
WO2009073534A2 (en) 2007-11-30 2009-06-11 Maxthera Inc. Bicyclic ppat inhibitors as antibacterial agents
US8697662B2 (en) 2009-05-27 2014-04-15 Ptc Therapeutics, Inc. Methods for treating Kaposi sarcoma
WO2010138685A1 (en) 2009-05-27 2010-12-02 Ptc Therapeutics, Inc. Methods for treating prostate conditions
HUE052510T2 (hu) 2009-05-27 2021-05-28 Ptc Therapeutics Inc Módszerek a rák és a nem daganatos állapotok kezelésére
MX2011012517A (es) 2009-05-27 2012-01-27 Ptc Therapeutics Inc Procesos para la preparacion de tetrahidro beta - carbolina sustituidas.
CN117865872A (zh) 2014-12-18 2024-04-12 豪夫迈·罗氏有限公司 四氢-吡啶并[3,4-b]吲哚雌激素受体调节剂及其用途
US20180002344A1 (en) 2016-06-16 2018-01-04 Genentech, Inc. Heteroaryl estrogen receptor modulators and uses thereof
KR20200035292A (ko) 2017-08-01 2020-04-02 피티씨 테라퓨틱스, 인크. 혈액 암 치료에 사용하기 위한 dhodh 억제제
TWI915239B (zh) 2018-06-21 2026-02-11 瑞士商赫孚孟拉羅股份公司 3-((1r,3r)-1-(2,6-二氟-4-((1-(3-氟丙基)氮雜環丁-3-基)胺基)苯基)-3-甲基-1,3,4,9-四氫-2h-吡啶并[3,4-b]吲哚-2-基)-2,2-二氟丙-1-醇之固體形式及用於製備包含經取代苯基或吡啶基部分之稠合三環化合物之製程，包括其使用方法
US12371429B2 (en) 2018-08-16 2025-07-29 Recreo Pharmaceuticals Llc Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CO5370679A1 (es) * 1999-06-01 2004-02-27 Smithkline Beecham Corp Inhibidores fab 1
UA74826C2 (en) * 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors

Also Published As

Publication number Publication date
EP1347759B1 (de) 2005-06-29
WO2002062339A1 (en) 2002-08-15
JP2004532816A (ja) 2004-10-28
ES2241902T3 (es) 2005-11-01
DE60111774D1 (de) 2005-08-04
EP1347759A4 (de) 2004-04-21
EP1347759A1 (de) 2003-10-01
US20040053954A1 (en) 2004-03-18
DE60111774T2 (de) 2006-05-04
US6987115B2 (en) 2006-01-17

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties