DE60105411D1 - Verfahren zur diagnose von krebs - Google Patents
Verfahren zur diagnose von krebsInfo
- Publication number
- DE60105411D1 DE60105411D1 DE60105411T DE60105411T DE60105411D1 DE 60105411 D1 DE60105411 D1 DE 60105411D1 DE 60105411 T DE60105411 T DE 60105411T DE 60105411 T DE60105411 T DE 60105411T DE 60105411 D1 DE60105411 D1 DE 60105411D1
- Authority
- DE
- Germany
- Prior art keywords
- diagnosing cancer
- diagnosing
- cancers
- rna
- evolution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00111370 | 2000-05-26 | ||
EP00111370A EP1158055A1 (de) | 2000-05-26 | 2000-05-26 | Verfahren zur Diagnose von Krebs |
PCT/IB2001/000852 WO2001090409A1 (fr) | 2000-05-26 | 2001-05-16 | Methode pour le diagnostic de cancers |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60105411D1 true DE60105411D1 (de) | 2004-10-14 |
DE60105411T2 DE60105411T2 (de) | 2005-09-22 |
Family
ID=8168848
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60105411T Expired - Lifetime DE60105411T2 (de) | 2000-05-26 | 2001-05-16 | Verfahren zur diagnose von krebs |
Country Status (8)
Country | Link |
---|---|
US (1) | US7163789B2 (de) |
EP (2) | EP1158055A1 (de) |
AT (1) | ATE275642T1 (de) |
AU (1) | AU5502101A (de) |
DE (1) | DE60105411T2 (de) |
ES (1) | ES2227178T3 (de) |
PT (1) | PT1283907E (de) |
WO (1) | WO2001090409A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6607898B1 (en) * | 1996-03-26 | 2003-08-19 | Oncomedx, Inc. | Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum |
US20030158673A1 (en) * | 2002-02-16 | 2003-08-21 | Ingene Institut Fur Genetische Medizin Gmbh | Method for creating a blood bank with associated data bank |
ITMI20022743A1 (it) | 2002-12-23 | 2004-06-24 | Ist Naz Stud Cura Dei Tumori | Metodo per la determinazione del rischio di comparsa, della presenza o del decorso di malattie tumorali. |
ATE346170T1 (de) * | 2003-10-29 | 2006-12-15 | Maurice Stroun | Verfahren zur diagnose von krebs |
PL1712639T3 (pl) | 2005-04-06 | 2009-02-27 | Maurice Stroun | Sposób diagnozowania nowotworu przez wykrywanie krążącego DNA i RNA |
US8768629B2 (en) * | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
JP2009537154A (ja) | 2006-05-18 | 2009-10-29 | モレキュラー プロファイリング インスティテュート, インコーポレイテッド | 疾患状態に対する個別化された医学的介入を決定するためのシステムおよび方法 |
US8252529B2 (en) * | 2008-06-12 | 2012-08-28 | The Invention Science Fund I, Llc | Methods for collecting and detecting oligonucleotides |
US8252528B2 (en) * | 2008-06-12 | 2012-08-28 | The Invention Science Fund I, Llc | Methods, compositions, and kits for collecting and detecting oligonucleotides |
US8614057B2 (en) * | 2008-06-12 | 2013-12-24 | The Invention Science Fund I, Llc | Methods for collecting and detecting oligonucleotides |
CA2743211A1 (en) | 2008-11-12 | 2010-05-20 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Methods and systems of using exosomes for determining phenotypes |
AU2011223789A1 (en) | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
NZ611599A (en) | 2010-11-30 | 2015-05-29 | Univ Hong Kong Chinese | Detection of genetic or molecular aberrations associated with cancer |
WO2013052168A2 (en) * | 2011-05-26 | 2013-04-11 | Georgetown University | Detection aib1-delta 4 protein |
US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
IL305303A (en) | 2012-09-04 | 2023-10-01 | Guardant Health Inc | Systems and methods for detecting rare mutations and changes in number of copies |
JP6571665B2 (ja) | 2013-12-28 | 2019-09-04 | ガーダント ヘルス, インコーポレイテッド | 遺伝的バリアントを検出するための方法およびシステム |
US11302416B2 (en) | 2015-09-02 | 2022-04-12 | Guardant Health | Machine learning for somatic single nucleotide variant detection in cell-free tumor nucleic acid sequencing applications |
CN108603228B (zh) | 2015-12-17 | 2023-09-01 | 夸登特健康公司 | 通过分析无细胞dna确定肿瘤基因拷贝数的方法 |
ES2840003T3 (es) | 2016-09-30 | 2021-07-06 | Guardant Health Inc | Métodos para análisis multi-resolución de ácidos nucleicos libres de células |
US9850523B1 (en) | 2016-09-30 | 2017-12-26 | Guardant Health, Inc. | Methods for multi-resolution analysis of cell-free nucleic acids |
US10907211B1 (en) | 2017-02-16 | 2021-02-02 | Quantgene Inc. | Methods and compositions for detecting cancer biomarkers in bodily fluids |
AU2020216438A1 (en) | 2019-01-31 | 2021-07-29 | Guardant Health, Inc. | Compositions and methods for isolating cell-free DNA |
US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4699877A (en) | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5274087A (en) | 1986-08-13 | 1993-12-28 | Molecular Diagnostics, Inc. | cDNA coding for carcinoembryonic antigen (CEA) |
DE3717212A1 (de) | 1987-05-22 | 1988-12-08 | Viktor Dr Dr Med Balazs | Verfahren zur untersuchung einer azellularen biologischen fluessigkeit auf zellulare onkogen-transkripte bzw. deren fragmente |
US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
US4874858A (en) | 1988-03-28 | 1989-10-17 | The B. F. Goodrich Company | Triazine-containing multisilane coupling agents for coating glass fibers, for adhesives, and for protective coatings |
US4999290A (en) | 1988-03-31 | 1991-03-12 | The Board Of Regents, The University Of Texas System | Detection of genomic abnormalities with unique aberrant gene transcripts |
US5098890A (en) | 1988-11-07 | 1992-03-24 | Temple University-Of The Commonwealth System Of Higher Education | Antisence oligonucleotides to c-myb proto-oncogene and uses thereof |
US5087617A (en) | 1989-02-15 | 1992-02-11 | Board Of Regents, The University Of Texas System | Methods and compositions for treatment of cancer using oligonucleotides |
WO1990009456A1 (de) | 1989-02-16 | 1990-08-23 | Viktor Balazs | Malignitätstest (krebs-test) mit verwendung von der polymerasekettenreaktion |
US5217889A (en) | 1990-10-19 | 1993-06-08 | Roninson Igor B | Methods and applications for efficient genetic suppressor elements |
US5155018A (en) | 1991-07-10 | 1992-10-13 | Hahnemann University | Process and kit for isolating and purifying RNA from biological sources |
AU3729393A (en) | 1992-02-20 | 1993-09-13 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University, The | Boomerand DNA amplification |
US5300635A (en) | 1993-02-01 | 1994-04-05 | University Of Iowa Research Foundation | Quaternary amine surfactants and methods of using same in isolation of nucleic acids |
US6582904B2 (en) * | 1995-11-16 | 2003-06-24 | Michael W. Dahm | Method of quantifying tumour cells in a body fluid and a suitable test kit |
US5817461A (en) * | 1996-01-03 | 1998-10-06 | Hamilton Civic Hospitals Research Development Inc. | Methods and compositions for diagnosis of hyperhomocysteinemia |
US6329179B1 (en) * | 1996-03-26 | 2001-12-11 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
US6607898B1 (en) * | 1996-03-26 | 2003-08-19 | Oncomedx, Inc. | Method for detection of hTR and hTERT telomerase-associated RNA in plasma or serum |
AU734089B2 (en) * | 1996-10-01 | 2001-06-07 | Geron Corporation | Human telomerase catalytic subunit |
US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
AU733610B2 (en) * | 1996-12-20 | 2001-05-17 | Geron Corporation | Methods for detecting and inhibiting the RNA component of telomerase |
DE19757300A1 (de) * | 1997-12-22 | 1999-06-24 | Roche Diagnostics Gmbh | Nachweis von Harnblasenkarzinom in einer Urinprobe |
DE19804372A1 (de) | 1998-02-04 | 1999-08-05 | Michael W Dr Dr Dahm | Verfahren zur quantitativen Bestimmung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits |
JP2002503480A (ja) * | 1998-02-16 | 2002-02-05 | ユニバーシティ オブ メリーランド, ボルチモア | がんスクリーニングならびに疾病段階および予後の評価のための体液のテロメラーゼ・アッセイ |
CA2291798A1 (en) * | 1998-03-26 | 1999-10-07 | Kyowa Hakko Kogyo Co., Ltd. | Monoclonal antibody against human telomerase catalytic subunit |
-
2000
- 2000-05-26 EP EP00111370A patent/EP1158055A1/de not_active Withdrawn
-
2001
- 2001-05-16 AU AU55021/01A patent/AU5502101A/en not_active Abandoned
- 2001-05-16 EP EP01928158A patent/EP1283907B1/de not_active Expired - Lifetime
- 2001-05-16 DE DE60105411T patent/DE60105411T2/de not_active Expired - Lifetime
- 2001-05-16 US US10/296,739 patent/US7163789B2/en not_active Expired - Lifetime
- 2001-05-16 PT PT01928158T patent/PT1283907E/pt unknown
- 2001-05-16 WO PCT/IB2001/000852 patent/WO2001090409A1/fr active IP Right Grant
- 2001-05-16 AT AT01928158T patent/ATE275642T1/de active
- 2001-05-16 ES ES01928158T patent/ES2227178T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1283907A1 (de) | 2003-02-19 |
ES2227178T3 (es) | 2005-04-01 |
ATE275642T1 (de) | 2004-09-15 |
AU5502101A (en) | 2001-12-03 |
PT1283907E (pt) | 2005-01-31 |
US20040132019A1 (en) | 2004-07-08 |
US7163789B2 (en) | 2007-01-16 |
WO2001090409A1 (fr) | 2001-11-29 |
EP1283907B1 (de) | 2004-09-08 |
DE60105411T2 (de) | 2005-09-22 |
EP1158055A1 (de) | 2001-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |