DE60045075D1 - Anti-epha2 antikörper als krebsdiagnostikum - Google Patents
Anti-epha2 antikörper als krebsdiagnostikumInfo
- Publication number
- DE60045075D1 DE60045075D1 DE60045075T DE60045075T DE60045075D1 DE 60045075 D1 DE60045075 D1 DE 60045075D1 DE 60045075 T DE60045075 T DE 60045075T DE 60045075 T DE60045075 T DE 60045075T DE 60045075 D1 DE60045075 D1 DE 60045075D1
- Authority
- DE
- Germany
- Prior art keywords
- cancer diagnostic
- epha2
- epha2 antibody
- kits
- overexpressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14925999P | 1999-08-17 | 1999-08-17 | |
PCT/US2000/022669 WO2001012840A2 (en) | 1999-08-17 | 2000-08-17 | Anti-epha2 antibodies as a cancer diagnostic |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60045075D1 true DE60045075D1 (de) | 2010-11-18 |
Family
ID=22529464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60045075T Expired - Lifetime DE60045075D1 (de) | 1999-08-17 | 2000-08-17 | Anti-epha2 antikörper als krebsdiagnostikum |
Country Status (8)
Country | Link |
---|---|
EP (2) | EP2312316A1 (de) |
JP (3) | JP4948728B2 (de) |
AT (1) | ATE483978T1 (de) |
AU (1) | AU785445C (de) |
CA (1) | CA2382655A1 (de) |
DE (1) | DE60045075D1 (de) |
ES (1) | ES2357296T3 (de) |
WO (1) | WO2001012840A2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6927203B1 (en) | 1999-08-17 | 2005-08-09 | Purdue Research Foundation | Treatment of metastatic disease |
US7192698B1 (en) | 1999-08-17 | 2007-03-20 | Purdue Research Foundation | EphA2 as a diagnostic target for metastatic cancer |
MXPA02009454A (es) | 2000-03-31 | 2003-04-10 | Purdue Research Foundation | Metodo de tratamiento usando conjugados ligando-inmunogeno. |
US7101976B1 (en) | 2000-09-12 | 2006-09-05 | Purdue Research Foundation | EphA2 monoclonal antibodies and methods of making and using same |
AU2002314433A1 (en) * | 2001-07-02 | 2003-01-21 | Licentia Ltd. | Ephrin-tie receptor materials and methods |
ATE451935T1 (de) * | 2001-09-28 | 2010-01-15 | Purdue Research Foundation | Behandlungsverfahren mit liganden- immunogenkonjugaten |
WO2003040304A2 (en) * | 2001-11-09 | 2003-05-15 | Neuronova Ab | Method of proliferation in neurogenic regions |
EP2075256A2 (de) | 2002-01-14 | 2009-07-01 | William Herman | Gezielte Liganden |
CA2485548A1 (en) * | 2002-05-10 | 2004-02-19 | Purdue Research Foundation | Epha2 agonistic monoclonal antibodies and methods of use thereof |
AU2003243228B2 (en) * | 2002-05-10 | 2009-03-26 | Medimmune, Llc | EphA2 monoclonal antibodies and methods of use thereof |
EP1505999A4 (de) | 2002-05-23 | 2009-07-08 | Purdue Research Foundation | Niedermolekulare protein-tyrosinphosphatase (lmw-ptp) als diagnostisches und therapeutisches target |
WO2004101764A2 (en) * | 2003-05-13 | 2004-11-25 | Chiron Corporation | Methods of modulating metastasis and skeletal related events resulting from metastases |
AU2004281834A1 (en) * | 2003-10-15 | 2005-04-28 | Cerus Corporation | Listeria-based EphA2 vaccines |
JP2008510008A (ja) | 2004-08-16 | 2008-04-03 | メディミューン,インコーポレーテッド | 抗体依存性細胞性細胞傷害活性が増強されたインテグリンアンタゴニスト |
ZA200707275B (en) * | 2005-02-04 | 2009-01-28 | Raven Biotechnologies Inc | Antibodies that bind to EphA2 and methods of use thereof |
WO2007092299A2 (en) | 2006-02-03 | 2007-08-16 | Purdue Research Foundation | Targeted conjugates and radiation |
RU2525133C2 (ru) | 2007-08-30 | 2014-08-10 | Дайити Санкио Компани, Лимитед | Антитело к epha2 |
JP5875054B2 (ja) * | 2013-02-13 | 2016-03-02 | 国立大学法人 東京大学 | がんの検査方法及び検査用キット |
JP6069806B2 (ja) * | 2013-02-13 | 2017-02-01 | 国立大学法人 東京大学 | がんの検査方法及び検査用キット |
JP6399013B2 (ja) * | 2016-02-18 | 2018-10-03 | トヨタ自動車株式会社 | 化学蓄熱器の制御装置 |
JP6729917B2 (ja) * | 2016-08-19 | 2020-07-29 | 国立大学法人 東京大学 | EphA2 N末端フラグメント抗体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU663727B2 (en) | 1991-08-22 | 1995-10-19 | Becton Dickinson & Company | Methods and compositions for cancer therapy and for prognosticating responses to cancer therapy |
US5457048A (en) * | 1993-12-03 | 1995-10-10 | La Jolla Cancer Research Foundation | Eph-related tyrosine kinases, nucleotide sequences and methods of use |
US5876949A (en) | 1995-05-31 | 1999-03-02 | The Trustees Of The University Of Pennsylvania | Antibodies specific for fragile X related proteins and method of using the same |
-
2000
- 2000-08-17 EP EP10178275A patent/EP2312316A1/de not_active Withdrawn
- 2000-08-17 WO PCT/US2000/022669 patent/WO2001012840A2/en active IP Right Grant
- 2000-08-17 AU AU67843/00A patent/AU785445C/en not_active Ceased
- 2000-08-17 EP EP00955686A patent/EP1210603B1/de not_active Expired - Lifetime
- 2000-08-17 AT AT00955686T patent/ATE483978T1/de not_active IP Right Cessation
- 2000-08-17 ES ES00955686T patent/ES2357296T3/es not_active Expired - Lifetime
- 2000-08-17 CA CA002382655A patent/CA2382655A1/en not_active Abandoned
- 2000-08-17 JP JP2001516927A patent/JP4948728B2/ja not_active Expired - Fee Related
- 2000-08-17 DE DE60045075T patent/DE60045075D1/de not_active Expired - Lifetime
-
2007
- 2007-08-15 JP JP2007211843A patent/JP2007291140A/ja active Pending
-
2011
- 2011-12-28 JP JP2011287158A patent/JP2012103264A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU785445B2 (en) | 2007-06-14 |
EP2312316A1 (de) | 2011-04-20 |
JP4948728B2 (ja) | 2012-06-06 |
WO2001012840A2 (en) | 2001-02-22 |
JP2007291140A (ja) | 2007-11-08 |
EP1210603A2 (de) | 2002-06-05 |
AU6784300A (en) | 2001-03-13 |
AU785445C (en) | 2008-01-31 |
WO2001012840A3 (en) | 2001-05-03 |
WO2001012840B1 (en) | 2001-09-27 |
CA2382655A1 (en) | 2001-02-22 |
ATE483978T1 (de) | 2010-10-15 |
JP2003507023A (ja) | 2003-02-25 |
ES2357296T3 (es) | 2011-04-25 |
EP1210603B1 (de) | 2010-10-06 |
JP2012103264A (ja) | 2012-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60045075D1 (de) | Anti-epha2 antikörper als krebsdiagnostikum | |
EP1585966B8 (de) | Behandlung von Krebs mit dem anti-ErbB2-Antikörper rhuMAb 2C4 | |
WO2000052204A3 (en) | Gene expression in bladder tumors | |
NZ597363A (en) | Prognosis prediction for colorectal cancer | |
RU2005131842A (ru) | Моноклональное антитело и продуцирующая его гибридома | |
DK1242060T3 (da) | Behandling af metastatisk sygdom | |
WO2005113000A3 (en) | Anti-cancer activity of an anti-thymidine kinase monoclonal antibody | |
CA2384579A1 (en) | Early cancer tumor marker | |
ATE238555T1 (de) | Krebsbehandlung | |
WO2001075177A3 (en) | Tumor markers in ovarian cancer | |
WO2004056874A3 (en) | Neuropilin-1 inhibitors | |
WO2007121465A3 (en) | Detection of proteins from circulating neoplastic cells | |
CN111273012B (zh) | 一种血清自身抗体联合检测的方法 | |
WO2008019201A3 (en) | Enhanced diagnostic multimarker serological profiling | |
WO2007111875A3 (en) | Methods for diagnosing and treating kidney and colorectal cancer | |
WO2003087760A3 (en) | Methods for detecting bcr-abl signaling activity in tissues using phospho- specific antibodies | |
CN101042402A (zh) | 用于癌症诊断的自身抗体检测 | |
EP0163303A3 (de) | Menschliche monoklonale Antikörper gegen Zelloberflächen- oder Innenzellantigene | |
HK1126278A1 (en) | Identification of non-small cell lung carcinoma (nsclc) tumors expressing pdgfr-alpha pdgfr(nsclc) | |
DK1214447T3 (da) | Påvisning af pyruvatkinase-isoenzymer i fæces | |
WO2005114203A3 (en) | Dominant b cell epitopes and methods of making and using thereof | |
SE9500030D0 (sv) | Method of determining metastatic potential of tumor cells | |
ATE394676T1 (de) | Verbindungen und verfahren zur diagnose von prostatakrebs | |
AU2002306568A1 (en) | Forms of prostate specific antigens and methods for their detection | |
Xie et al. | Expression of IL-33 in colorectal cancer and its association with clinical features |