DE60044746D1 - Amphipathische verbindung mit dendritischer struktur - Google Patents

Amphipathische verbindung mit dendritischer struktur

Info

Publication number
DE60044746D1
DE60044746D1 DE60044746T DE60044746T DE60044746D1 DE 60044746 D1 DE60044746 D1 DE 60044746D1 DE 60044746 T DE60044746 T DE 60044746T DE 60044746 T DE60044746 T DE 60044746T DE 60044746 D1 DE60044746 D1 DE 60044746D1
Authority
DE
Germany
Prior art keywords
amphipathic
connection
dendritical
dendritical structure
amphipathic connection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60044746T
Other languages
English (en)
Inventor
Eishun Tsuchida
Shinji Takeoka
Keitaro Sou
Haruki Ohkawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waseda University
Original Assignee
Waseda University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waseda University filed Critical Waseda University
Application granted granted Critical
Publication of DE60044746D1 publication Critical patent/DE60044746D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Polyamides (AREA)
  • Polyethers (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
DE60044746T 1999-08-31 2000-08-24 Amphipathische verbindung mit dendritischer struktur Expired - Lifetime DE60044746D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24573199A JP3181276B2 (ja) 1999-08-31 1999-08-31 樹枝状分岐構造を持つ両親媒性化合物
PCT/JP2000/005702 WO2001016211A1 (fr) 1999-08-31 2000-08-24 Compose amphipathique a structure dendritique

Publications (1)

Publication Number Publication Date
DE60044746D1 true DE60044746D1 (de) 2010-09-09

Family

ID=17137974

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60044746T Expired - Lifetime DE60044746D1 (de) 1999-08-31 2000-08-24 Amphipathische verbindung mit dendritischer struktur

Country Status (5)

Country Link
US (1) US6933352B2 (de)
EP (1) EP1219659B1 (de)
JP (1) JP3181276B2 (de)
DE (1) DE60044746D1 (de)
WO (1) WO2001016211A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE471956T1 (de) * 2001-01-30 2010-07-15 Kyowa Hakko Kirin Co Ltd Verzweigte polyalkylenglykole
JP4678967B2 (ja) * 2001-03-08 2011-04-27 本田技研工業株式会社 ゲル化性有機化合物及びそれを用いるゲル
US9389227B2 (en) * 2001-09-05 2016-07-12 Posco Solid substrate comprising array of dendrons and methods for using the same
JP2004307404A (ja) 2003-04-08 2004-11-04 Nipro Corp 人工酸素運搬体を含む医薬組成物
JP2005154514A (ja) * 2003-11-21 2005-06-16 Univ Waseda 機能性生分解性材料およびその製造方法
WO2006018063A1 (en) * 2004-08-17 2006-02-23 Unilever Plc Hair care composition comprising a dendritic macromolecule
JP5038128B2 (ja) * 2005-03-16 2012-10-03 日本ケミカルリサーチ株式会社 薬物運搬体
US8647613B2 (en) 2005-03-16 2014-02-11 Jcr Pharmaceuticals Co., Ltd. Drug carrier
US7960442B2 (en) 2005-04-20 2011-06-14 International Business Machines Corporation Nanoporous media templated from unsymmetrical amphiphilic porogens
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid
US7723438B2 (en) * 2005-04-28 2010-05-25 International Business Machines Corporation Surface-decorated polymeric amphiphile porogens for the templation of nanoporous materials
WO2006132388A1 (en) 2005-06-06 2006-12-14 Waseda University Bone marrow-directing drug delivery materials and their applications
JP4991168B2 (ja) * 2006-03-10 2012-08-01 大阪瓦斯株式会社 新規デンドリマー
US7674781B2 (en) * 2006-04-28 2010-03-09 Heather Sheardown Hyaluronic acid-retaining polymers
WO2007140282A1 (en) * 2006-05-24 2007-12-06 Peg Biosciences Peg linker compounds and biologically active conjugates thereof
AU2007296190A1 (en) * 2006-09-15 2008-03-20 Enzon Pharmaceuticals, Inc. Lysine-based polymeric linkers
CN101516491B (zh) * 2006-09-27 2012-08-08 西巴控股有限公司 聚亚乙基亚胺型树枝状分散剂
US8241647B2 (en) 2007-05-17 2012-08-14 Waseda University Amphiphilic molecule, molecular assembly comprising the amphiphilic molecule, and use of the molecular assembly
CN106995465B (zh) * 2016-01-25 2019-11-01 沈阳药科大学 一种化合物及其应用以及一种铂类配合物及其脂质体
CN106832056B (zh) * 2017-02-24 2019-08-06 中国药科大学 硫酸化透明质酸2-辛基十二醇酯
CN110028678A (zh) * 2019-04-03 2019-07-19 同济大学 高代树枝状聚赖氨酸及其制备方法
US20240247032A1 (en) * 2021-08-23 2024-07-25 Kaohsiung Medical University Method of synthesizing dendrimeric amphiphile
US11851454B2 (en) 2021-12-30 2023-12-26 Hongene Biotech Corporation Compositions and methods for liquid phase oligonucleotide synthesis
WO2023249905A1 (en) * 2022-06-21 2023-12-28 Hongene Biotech Corporation Compositions and methods for liquid phase oligonucleotide synthesis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560929A (en) * 1986-08-18 1996-10-01 The Dow Chemical Company Structured copolymers and their use as absorbents, gels and carriers of metal ions
US5229490A (en) 1987-05-06 1993-07-20 The Rockefeller University Multiple antigen peptide system
JPH07505915A (ja) * 1992-04-14 1995-06-29 コーネル　リサーチ　ファウンデーション、インコーポレーテッド 樹枝状巨大分子およびその製造法
EP0638060A4 (de) * 1992-04-21 1995-04-19 Univ South Florida T-butyl-kaskaden polymere.
US5739218A (en) * 1997-06-02 1998-04-14 Dow Corning Corporation Radially layered copoly (amidoamine-organosilicon) dendrimers
US5902863A (en) * 1997-07-21 1999-05-11 Dow Corning Corporation Dendrimer-based networks containing lyophilic organosilicon and hydrophilic polyamidoamine nanoscopic domains
JPH11296638A (ja) 1998-04-10 1999-10-29 Nippon Telegr & Teleph Corp <Ntt> Ｉｃカード

Also Published As

Publication number Publication date
EP1219659A1 (de) 2002-07-03
EP1219659A4 (de) 2004-03-17
US20020120096A1 (en) 2002-08-29
JP2001064383A (ja) 2001-03-13
EP1219659B1 (de) 2010-07-28
JP3181276B2 (ja) 2001-07-03
WO2001016211A1 (fr) 2001-03-08
US6933352B2 (en) 2005-08-23

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