DE60040608D1 - Bioproduktion von para-hydroxy-zimtsäure - Google Patents

Bioproduktion von para-hydroxy-zimtsäure

Info

Publication number
DE60040608D1
DE60040608D1 DE60040608T DE60040608T DE60040608D1 DE 60040608 D1 DE60040608 D1 DE 60040608D1 DE 60040608 T DE60040608 T DE 60040608T DE 60040608 T DE60040608 T DE 60040608T DE 60040608 D1 DE60040608 D1 DE 60040608D1
Authority
DE
Germany
Prior art keywords
phca
pal
developing
yeast
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60040608T
Other languages
English (en)
Inventor
Xiao-Song Tang
Todd M Vannelli
Wei Wei Qi
Sima Sariaslani
Anthony A Gatenby
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of DE60040608D1 publication Critical patent/DE60040608D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60040608T 1999-08-06 2000-08-03 Bioproduktion von para-hydroxy-zimtsäure Expired - Lifetime DE60040608D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14771999P 1999-08-06 1999-08-06
PCT/US2000/021156 WO2001011071A2 (en) 1999-08-06 2000-08-03 Bioproduction of para-hydroxycinnamic acid

Publications (1)

Publication Number Publication Date
DE60040608D1 true DE60040608D1 (de) 2008-12-04

Family

ID=22522651

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60040608T Expired - Lifetime DE60040608D1 (de) 1999-08-06 2000-08-03 Bioproduktion von para-hydroxy-zimtsäure

Country Status (5)

Country Link
EP (1) EP1226265B1 (de)
JP (1) JP4786844B2 (de)
AT (1) ATE412060T1 (de)
DE (1) DE60040608D1 (de)
WO (1) WO2001011071A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6368837B1 (en) * 1999-08-06 2002-04-09 E. I. Du Pont Nemours And Company Bioproduction of para-hydroxycinnamic acid
US6521748B2 (en) 1999-08-06 2003-02-18 E. I. Du Pont De Nemours And Company Polynucleotide encoding a mutant Rhodotorula glutinis tyrosine ammonia lyase polypeptide
JP2005522180A (ja) * 2001-05-04 2005-07-28 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー チロシン、桂皮酸およびパラ−ヒドロキシ桂皮酸の産生方法
US7879582B2 (en) 2002-02-26 2011-02-01 E. I. Du Pont De Nemours And Company Method for the recombination of genetic elements
US6951751B2 (en) * 2002-05-23 2005-10-04 E. I. Du Pont De Nemours And Company DNA and amino acid sequences of a tyrosine-inducible tyrosine ammonia lyase enzyme from the yeast Trichosporon cutaneum
EP1589112A1 (de) * 2004-04-21 2005-10-26 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO Mikrobielle Herstellung aromatischer Säuren
CN103409449A (zh) * 2012-09-18 2013-11-27 江南大学 一种粘红酵母苯丙氨酸脱氨酶基因克隆及在大肠菌种的高效表达方法
EP3714056A1 (de) 2017-11-20 2020-09-30 Axxence Holding B.V. Herstellung einer aromaverbindung in einer wirtszelle
CN111849794B (zh) * 2020-06-29 2022-05-31 扬州大学 一种酿酒酵母重组菌及其构建方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636466A (en) * 1983-10-31 1987-01-13 Genex Corporation Phenylalanine ammonia lyase-producing microbial cells
JPH0673459B2 (ja) * 1985-10-31 1994-09-21 工業技術院長 ラット肝チトクロムｐ―４５０ｃおよびｎａｄｐｈ―チトクロムｐ―４５０還元酵素を同時に酵母内で発現させることを目的とした発現用プラスミドｐａｒｍ１，ならびにｐａｒｍ１を菌体内に保持する酵母菌体
JP2507345B2 (ja) * 1986-09-16 1996-06-12 三井東圧化学株式会社 Ｌ―フェニルアラニン―アンモニアリ・ア―ゼ構造遺伝子
JP2525413B2 (ja) * 1987-06-18 1996-08-21 三井東圧化学株式会社 Ｌ−フェニルアラニン・アンモニアリア−ゼ発現用組換え体プラスミド及び該プラスミドを有する形質転換株
US4946790A (en) * 1987-02-06 1990-08-07 Mitsui Toatsu Chemicals, Inc. Recombinant plasmid for the expression of L-phenylalanine ammonia-lyase and transformed strain carrying same
DE69122016T2 (de) * 1990-09-26 1997-04-30 Sumitomo Chemical Co Mitochondriales P450
EP0618972A1 (de) * 1991-12-16 1994-10-12 E.I. Du Pont De Nemours And Company KONSTITUTIVE EXPRESSION VON P450-SOY UND FERREDOXIN-SOY IN -i(STREPTOMYCETEN), UND BIOTRANSFORMATION VON CHEMIKALIEN DURCH REKOMBINANTE ORGANISMEN
DK72992D0 (da) * 1992-06-01 1992-06-01 Novo Nordisk As Enzym

Also Published As

Publication number Publication date
WO2001011071A3 (en) 2001-06-07
JP4786844B2 (ja) 2011-10-05
JP2003506096A (ja) 2003-02-18
EP1226265B1 (de) 2008-10-22
WO2001011071A2 (en) 2001-02-15
ATE412060T1 (de) 2008-11-15
EP1226265A2 (de) 2002-07-31

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DE60040608D1 (de) Bioproduktion von para-hydroxy-zimtsäure
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