DE60038664D1 - Genträger - Google Patents
GenträgerInfo
- Publication number
- DE60038664D1 DE60038664D1 DE60038664T DE60038664T DE60038664D1 DE 60038664 D1 DE60038664 D1 DE 60038664D1 DE 60038664 T DE60038664 T DE 60038664T DE 60038664 T DE60038664 T DE 60038664T DE 60038664 D1 DE60038664 D1 DE 60038664D1
- Authority
- DE
- Germany
- Prior art keywords
- gene carriers
- gene
- carriers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP31947099 | 1999-11-10 | ||
JP31947099 | 1999-11-10 | ||
JP2000142897 | 2000-05-16 | ||
JP2000142897 | 2000-05-16 | ||
PCT/JP2000/007875 WO2001034207A1 (fr) | 1999-11-10 | 2000-11-09 | Supports de genes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60038664D1 true DE60038664D1 (de) | 2008-06-05 |
DE60038664T2 DE60038664T2 (de) | 2009-05-28 |
Family
ID=26569729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60038664T Expired - Lifetime DE60038664T2 (de) | 1999-11-10 | 2000-11-09 | Genträger |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1142591B1 (de) |
JP (1) | JP4064108B2 (de) |
DE (1) | DE60038664T2 (de) |
WO (1) | WO2001034207A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002237559B2 (en) * | 2001-03-13 | 2006-10-26 | Japan Science And Technology Agency | Gene carriers with the use of polysaccharide and process for producing the same |
EP1625850B1 (de) * | 2003-05-15 | 2012-02-29 | Japan Science and Technology Agency | Immunostimulierende mittel |
JP2005080598A (ja) * | 2003-09-10 | 2005-03-31 | Japan Science & Technology Agency | β−1,3−グルカン誘導体を用いるプラスミドDNAの導入法 |
JP2005204612A (ja) * | 2004-01-26 | 2005-08-04 | Japan Science & Technology Agency | 新規な遺伝子導入法 |
JP2005255750A (ja) * | 2004-03-10 | 2005-09-22 | Japan Science & Technology Agency | ポリエチレングリコールまたはポリプロピレングリコール修飾β−1,3−グルカン系遺伝子キャリアー |
JP4712333B2 (ja) * | 2004-08-31 | 2011-06-29 | 独立行政法人科学技術振興機構 | ハイブリッド多糖系キャリアーを用いる核酸類の導入方法。 |
JP4841825B2 (ja) * | 2004-11-05 | 2011-12-21 | 独立行政法人科学技術振興機構 | ポリアニリン/β−1,3−グルカン複合体 |
WO2007058323A1 (ja) * | 2005-11-17 | 2007-05-24 | Napa Jenomics Co., Ltd. | 核酸ホモポリマー結合機能性核酸医薬品の製造法 |
JP5138954B2 (ja) * | 2006-03-09 | 2013-02-06 | 独立行政法人科学技術振興機構 | 両親媒性高分子複合体 |
JP4878915B2 (ja) * | 2006-05-25 | 2012-02-15 | 独立行政法人科学技術振興機構 | 核酸/多糖/カーボンナノチューブ複合体 |
CN101918554B (zh) | 2007-12-18 | 2013-07-03 | 独立行政法人产业技术综合研究所 | 多糖/双链rna复合物 |
WO2012008465A1 (ja) | 2010-07-16 | 2012-01-19 | ナパジェン ファーマ,インコーポレテッド | 核酸多糖複合体 |
US8852750B2 (en) | 2011-03-29 | 2014-10-07 | Wintershall Holding GmbH | Method for the coating of a cellulose material by using a glucan |
CN103459714A (zh) * | 2011-03-29 | 2013-12-18 | 巴斯夫欧洲公司 | 通过使用葡聚糖涂布纤维素材料的方法 |
WO2013191223A1 (ja) | 2012-06-20 | 2013-12-27 | 独立行政法人科学技術振興機構 | 核酸複合体および核酸多糖複合体 |
PL3048170T3 (pl) | 2013-09-20 | 2020-01-31 | National Institutes Of Biomedical Innovation, Health And Nutrition | Kompleks zawierający oligonukleotyd mający aktywność immunostymulującą i jego zastosowanie |
WO2015118789A1 (ja) * | 2014-02-06 | 2015-08-13 | 独立行政法人科学技術振興機構 | ペプチド/β-1,3-グルカン複合体及びその製造方法並びにそれを含む医薬組成物 |
JPWO2018174140A1 (ja) | 2017-03-23 | 2020-04-09 | ナパジェン ファーマ, インコーポレテッドNapaJen Pharma, Inc. | 癌細胞の接着活性阻害剤 |
US11793874B2 (en) | 2017-03-30 | 2023-10-24 | The University Of Kitakyushu | Immunity-inducing agent and pharmaceutical composition containing same |
CA3114149A1 (en) | 2018-09-28 | 2020-04-02 | The University Of Kitakyushu | Immunity-inducing agent comprising antigen peptide-adjuvant nucleotide conjugate and pharmaceutical composition comprising same |
WO2022102694A1 (ja) | 2020-11-12 | 2022-05-19 | 第一三共株式会社 | 粒子径が制御された、ベータグルカンと核酸との複合体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993008200A1 (en) * | 1991-10-15 | 1993-04-29 | Fmc Corporation | β-1,3-GLUCAN POLYSACCHARIDES, COMPOSITIONS, AND THEIR PREPARATION AND USES |
US5455344A (en) * | 1993-09-03 | 1995-10-03 | Fmc Corporation | Agarose compositions for nucleic acid sequencing |
WO1996014873A2 (en) * | 1994-11-16 | 1996-05-23 | Sri International | COVALENTLY BOUND β-GLUCAN CONJUGATES IN TARGETED DELIVERY |
DE19605279A1 (de) * | 1996-02-13 | 1997-08-14 | Hoechst Ag | Zielzellspezifische Vektoren für die Einschleusung von Genen in Zellen, Arzneimittel enthaltend derartige Vektoren und deren Verwendung |
-
2000
- 2000-11-09 EP EP00974855A patent/EP1142591B1/de not_active Expired - Lifetime
- 2000-11-09 DE DE60038664T patent/DE60038664T2/de not_active Expired - Lifetime
- 2000-11-09 WO PCT/JP2000/007875 patent/WO2001034207A1/ja active IP Right Grant
- 2000-11-09 JP JP2001536203A patent/JP4064108B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1142591A1 (de) | 2001-10-10 |
DE60038664T2 (de) | 2009-05-28 |
EP1142591A4 (de) | 2002-03-06 |
WO2001034207A1 (fr) | 2001-05-17 |
EP1142591B1 (de) | 2008-04-23 |
JP4064108B2 (ja) | 2008-03-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |