DE60038057D1 - Methode zur photoreduktion von hämoglobin-vesikeln - Google Patents

Methode zur photoreduktion von hämoglobin-vesikeln

Info

Publication number
DE60038057D1
DE60038057D1 DE60038057T DE60038057T DE60038057D1 DE 60038057 D1 DE60038057 D1 DE 60038057D1 DE 60038057 T DE60038057 T DE 60038057T DE 60038057 T DE60038057 T DE 60038057T DE 60038057 D1 DE60038057 D1 DE 60038057D1
Authority
DE
Germany
Prior art keywords
photoreduction
hemoglobin vesicles
vesicles
hemoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60038057T
Other languages
English (en)
Other versions
DE60038057T2 (de
Inventor
Eishun Tsuchida
Hiromi Sakai
Hiroto Onuma
Shinji Takeoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waseda University
Original Assignee
Waseda University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waseda University filed Critical Waseda University
Application granted granted Critical
Publication of DE60038057D1 publication Critical patent/DE60038057D1/de
Publication of DE60038057T2 publication Critical patent/DE60038057T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6445—Haemoglobin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
DE60038057T 2000-06-12 2000-12-25 Methode zur photoreduktion von hämoglobin-vesikeln Expired - Fee Related DE60038057T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000175611 2000-06-12
JP2000175611A JP4181290B2 (ja) 2000-06-12 2000-06-12 ヘモグロビン小胞体の光還元法
PCT/JP2000/009198 WO2001095930A1 (en) 2000-06-12 2000-12-25 Method of photoreduction of hemoglobin vesicles

Publications (2)

Publication Number Publication Date
DE60038057D1 true DE60038057D1 (de) 2008-03-27
DE60038057T2 DE60038057T2 (de) 2009-02-19

Family

ID=18677465

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60038057T Expired - Fee Related DE60038057T2 (de) 2000-06-12 2000-12-25 Methode zur photoreduktion von hämoglobin-vesikeln

Country Status (5)

Country Link
US (1) US6916303B2 (de)
EP (1) EP1297843B1 (de)
JP (1) JP4181290B2 (de)
DE (1) DE60038057T2 (de)
WO (1) WO2001095930A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6969367B2 (en) * 2000-02-02 2005-11-29 Xepmed, Inc. Extracorporeal pathogen reduction system
WO2003072130A1 (fr) 2002-02-27 2003-09-04 Oxygenix Co., Ltd. Systeme transporteur d'oxygene, transporteur d'oxygene articifiel et agent reducteur
CA2490959C (en) * 2002-07-02 2013-04-16 Board Of Regents, The University Of Texas System Radiolabeled compounds and liposomes and their methods of making and using the same
AU2004255268B2 (en) * 2003-07-09 2010-04-01 Loma Linda University Use of nitrite salts for the treatment of cardiovascular conditions
JP4763265B2 (ja) * 2003-10-23 2011-08-31 学校法人早稲田大学 メト化防止剤を含有する人工酸素運搬体
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US20060088583A1 (en) * 2004-10-25 2006-04-27 Oxygenix Co., Ltd. Artificial oxygen carrier containing preventive agents of metHb formation
JP4665791B2 (ja) * 2005-04-15 2011-04-06 ニプロ株式会社 酸素運搬体の脱一酸化炭素化方法、脱一酸化炭素化された酸素運搬体、その医薬組成物及び脱一酸化炭素化装置
EP2237788A4 (de) * 2007-12-27 2013-06-05 Aires Pharmaceuticals Inc Aerosolisierte nitrit- und stickoxidspendende verbindungen und ihre verwendung
CA2860158A1 (en) * 2011-01-07 2012-07-12 Somerset Group Enterprises, Inc. Modular extracorporeal systems and methods for treating blood-borne diseases
US9375525B2 (en) 2012-01-09 2016-06-28 Somerset Group Enterprises, Inc. Modular extracorporeal systems and methods for treating blood-borne diseases
JP2018509994A (ja) * 2015-03-27 2018-04-12 エリアス・セラピューティクス・インコーポレイテッドＥｌｉａｚ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 患者選択的アフェレシス
CN113564943A (zh) * 2021-07-09 2021-10-29 天津工业大学 一种电子介体强化的靛蓝全细胞还原染色方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578056A (en) * 1984-10-29 1986-03-25 Extracorporeal Medical Specialties, Inc. Patient photopheresis treatment apparatus and method
SU1424851A1 (ru) * 1986-12-08 1988-09-23 Научно-Исследовательский Институт Трансплантологии И Искусственных Органов Аппарат "вспомогательна печень
JPH0459735A (ja) * 1990-06-27 1992-02-26 Terumo Corp ヘモグロビン含有リポソーム
US5261874A (en) * 1991-09-16 1993-11-16 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Extra-corporeal blood access, sensing, and radiation methods and apparatuses
US5476764A (en) * 1994-09-16 1995-12-19 The Regents Of The University Of California Method using CO for extending the useful shelf-life of refrigerated red blood cells

Also Published As

Publication number Publication date
US6916303B2 (en) 2005-07-12
US20020095108A1 (en) 2002-07-18
EP1297843A4 (de) 2004-04-28
WO2001095930A1 (en) 2001-12-20
DE60038057T2 (de) 2009-02-19
EP1297843B1 (de) 2008-02-13
JP4181290B2 (ja) 2008-11-12
EP1297843A1 (de) 2003-04-02
JP2001354585A (ja) 2001-12-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee