DE60037655D1 - 4-(4-hydroxystyryl)pyridin-enthaltende substrate für analytabhängiges enzym aktivierungssystem - Google Patents

4-(4-hydroxystyryl)pyridin-enthaltende substrate für analytabhängiges enzym aktivierungssystem

Info

Publication number
DE60037655D1
DE60037655D1 DE60037655T DE60037655T DE60037655D1 DE 60037655 D1 DE60037655 D1 DE 60037655D1 DE 60037655 T DE60037655 T DE 60037655T DE 60037655 T DE60037655 T DE 60037655T DE 60037655 D1 DE60037655 D1 DE 60037655D1
Authority
DE
Germany
Prior art keywords
hydroxystyryl
pyridine
analyte
activation system
containing substrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60037655T
Other languages
English (en)
Other versions
DE60037655T2 (de
Inventor
Mark Norman Bobrow
Kevin Aaron Roth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PerkinElmer Health Sciences Inc
Original Assignee
PerkinElmer LAS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PerkinElmer LAS Inc filed Critical PerkinElmer LAS Inc
Publication of DE60037655D1 publication Critical patent/DE60037655D1/de
Application granted granted Critical
Publication of DE60037655T2 publication Critical patent/DE60037655T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20—Immunohistochemistry assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
DE60037655T 1999-03-17 2000-03-17 4-(4-hydroxystyryl)pyridin-enthaltende substrate für analytabhängiges enzym aktivierungssystem Expired - Fee Related DE60037655T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12482699P 1999-03-17 1999-03-17
US124826P 1999-03-17
US526594 2000-03-16
US09/526,594 US6355443B1 (en) 1999-03-17 2000-03-16 4-(4-hydroxystyryl) pyridine-containing substrates for an analyte dependent enzyme activation system
PCT/US2000/007229 WO2000055358A1 (en) 1999-03-17 2000-03-17 4-(4-hydroxystyryl)pyridine-containing substrates for an analyte dependent enzyme activation system

Publications (2)

Publication Number Publication Date
DE60037655D1 true DE60037655D1 (de) 2008-02-14
DE60037655T2 DE60037655T2 (de) 2008-11-27

Family

ID=26822989

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037655T Expired - Fee Related DE60037655T2 (de) 1999-03-17 2000-03-17 4-(4-hydroxystyryl)pyridin-enthaltende substrate für analytabhängiges enzym aktivierungssystem

Country Status (7)

Country Link
US (1) US6355443B1 (de)
EP (1) EP1161555B1 (de)
JP (1) JP2003524768A (de)
AT (1) ATE382705T1 (de)
CA (1) CA2368190A1 (de)
DE (1) DE60037655T2 (de)
WO (1) WO2000055358A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0487435A (ja) * 1990-07-31 1992-03-19 Fujitsu Ltd 回線分岐方式
EP1634074B1 (de) * 2003-06-12 2009-08-12 Perkinelmer Las, Inc. Hydrolytische substrate für ein analytabhängiges enzymaktivierungssystem
WO2006078941A2 (en) * 2005-01-20 2006-07-27 Sirtris Pharmaceuticals, Inc. Novel sirtuin activating compounds and methods of use thereof
WO2012092322A1 (en) * 2010-12-30 2012-07-05 Ventana Medical Systems, Inc. Enhanced deposition of chromogens utilizing pyrimidine analogs
WO2019236841A1 (en) 2018-06-08 2019-12-12 Ultivue, Inc. Multiplexed catalyzed reporter deposition
US11237170B2 (en) * 2018-12-04 2022-02-01 Aat Bioquest, Inc. Styryl phenols, derivatives and their use in methods of analyte detection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196306A (en) 1989-03-29 1993-03-23 E. I. Du Pont De Nemours And Company Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system
US5863748A (en) 1997-03-14 1999-01-26 New Life Science Products, Inc. p-Hydroxycinnamoyl-containing substrates for an analyte dependent enzyme activation system
DE69837683T2 (de) * 1998-06-04 2008-01-10 PerkinElmer LAS, Inc., Waltham Neuartige peroxidasesubstrate und ihre anwendung in katalysierten reporterbindungsassays

Also Published As

Publication number Publication date
US6355443B1 (en) 2002-03-12
EP1161555A1 (de) 2001-12-12
EP1161555A4 (de) 2004-12-22
CA2368190A1 (en) 2000-09-21
ATE382705T1 (de) 2008-01-15
EP1161555B1 (de) 2008-01-02
JP2003524768A (ja) 2003-08-19
DE60037655T2 (de) 2008-11-27
WO2000055358A1 (en) 2000-09-21
WO2000055358A9 (en) 2002-01-03

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee