DE60037218D1 - Pflaster und Verfahren zur transdermalen Verabreichung von Bupropion als freie base - Google Patents

Pflaster und Verfahren zur transdermalen Verabreichung von Bupropion als freie base

Info

Publication number
DE60037218D1
DE60037218D1 DE60037218T DE60037218T DE60037218D1 DE 60037218 D1 DE60037218 D1 DE 60037218D1 DE 60037218 T DE60037218 T DE 60037218T DE 60037218 T DE60037218 T DE 60037218T DE 60037218 D1 DE60037218 D1 DE 60037218D1
Authority
DE
Germany
Prior art keywords
bupropion
plaster
free base
transdermal administration
transdermal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60037218T
Other languages
English (en)
Inventor
Kamal K Midha
Hans E Junglinger
Mark Hirsh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PIERCE MAN LLP
Original Assignee
PIERCE MAN LLP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/309,075 external-priority patent/US6280763B1/en
Application filed by PIERCE MAN LLP filed Critical PIERCE MAN LLP
Application granted granted Critical
Publication of DE60037218D1 publication Critical patent/DE60037218D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60037218T 1999-05-10 2000-05-10 Pflaster und Verfahren zur transdermalen Verabreichung von Bupropion als freie base Expired - Lifetime DE60037218D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/309,075 US6280763B1 (en) 1999-05-10 1999-05-10 Apparatus and method for transdermal delivery of bupropion
US09/562,178 US6312716B1 (en) 1999-05-10 2000-05-02 Patch and method for transdermal delivery of bupropion base

Publications (1)

Publication Number Publication Date
DE60037218D1 true DE60037218D1 (de) 2008-01-10

Family

ID=26976597

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037218T Expired - Lifetime DE60037218D1 (de) 1999-05-10 2000-05-10 Pflaster und Verfahren zur transdermalen Verabreichung von Bupropion als freie base

Country Status (5)

Country Link
US (1) US6312716B1 (de)
EP (1) EP1051971B1 (de)
JP (1) JP2000327564A (de)
CA (1) CA2307958A1 (de)
DE (1) DE60037218D1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8545880B2 (en) * 1999-02-26 2013-10-01 Andrx Pharmaceuticals, Llc Controlled release oral dosage form
US6582737B2 (en) * 2001-09-25 2003-06-24 Peirce Management, Llc Pharmaceutical composition containing two active ingredients for smoking cessation
DE10148233A1 (de) * 2001-09-28 2003-04-10 Boehringer Ingelheim Pharma Verbindungen zur Reduzierung übermäßiger Nahrungsaufnahme
US6893660B2 (en) * 2002-11-21 2005-05-17 Andrx Pharmaceuticals, Inc. Stable pharmaceutical compositions without a stabilizer
US20040247623A1 (en) * 2003-03-24 2004-12-09 Roger Cady Method and article for treatment of sensory neuron related disorders through transdermal application of botulinum toxin
US20050112198A1 (en) * 2003-10-27 2005-05-26 Challapalli Prasad V. Bupropion formulation for sustained delivery
US20060204571A1 (en) * 2005-03-12 2006-09-14 Sun Pharmaceutical Industries Limited Stable compositions of bupropion or its pharmaceutically acceptable salts
AU2006252736A1 (en) * 2005-05-27 2006-12-07 Johnson & Johnson Consumer Companies, Inc. Discrete patch for viral lesions
WO2007117581A2 (en) * 2006-04-06 2007-10-18 Collegium Pharmaceutical, Inc. Stabilized transdermal bupropion preparations
WO2007120747A2 (en) * 2006-04-13 2007-10-25 Nupathe Inc. Transdermal methods and systems for the delivery of anti-migraine compounds
TWI541246B (zh) 2008-12-08 2016-07-11 歐陸斯迪公司 二氫羥戊甲嗎啡
GB2484977A (en) * 2010-10-29 2012-05-02 Biocopea Ltd Treatment of a Th-1 mediated disease
CN104603100A (zh) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 用于治疗炎症性肠病的组合物和方法
CN104603097A (zh) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 用于治疗多发性硬化症的组合物和方法
GB201309654D0 (en) 2013-05-30 2013-07-17 Euro Celtique Sa Method
EP3240779B1 (de) 2014-09-26 2020-10-28 Cellixbio Private Limited Zusammensetzungen und verfahren zur behandlung von epilepsie- und lipidstörungen
ES2799309T3 (es) 2014-09-29 2020-12-16 Cellix Bio Private Ltd Compuestos y composiciones para el tratamiento de esclerosis múltiple
WO2016067297A1 (en) 2014-10-27 2016-05-06 Cellix Bio Private Limited Salts of valproic acid with piperazine, ethylenediamine, lysine and/or eicosapentaenoic ecid (epa) amine derivatives for the treatment of epilepsy
EP3212626B1 (de) 2014-10-27 2018-11-07 Cellix Bio Private Limited Drei-komponenten-salze des fumarsäuremonomethylesters mit piperazin und ethylendiamin zur behandlung von multipler sclerosis
CN107207411A (zh) 2014-12-01 2017-09-26 塞尔利克斯生物私人有限公司 用于治疗多发性硬化的组合物和方法
EP3256459B1 (de) 2015-02-09 2022-07-13 Cellixbio Private Limited Zusammensetzungen und verfahren zur behandlung von mukositis
NZ750126A (en) 2016-08-11 2022-07-01 Cellix Bio Private Ltd Compositions and methods for the treatment of irritable bowel syndrome
RU2749189C2 (ru) 2016-10-04 2021-06-07 Целликс Био Прайвет Лимитед Композиции и способы лечения ксеростомии
WO2018115984A1 (en) 2016-12-19 2018-06-28 Cellix Bio Private Limited Compositions and methods for the treatment of inflammation
KR20200034769A (ko) 2017-07-27 2020-03-31 알러간, 인코포레이티드 체지방 감소를 위한 프로스타시클린 수용체 작용제
EP3651747A4 (de) 2017-11-17 2020-07-22 Cellix Bio Private Limited Zusammensetzungen und verfahren zur behandlung augenkrankheiten
NZ763699A (en) 2017-11-17 2022-05-27 Cellix Bio Private Ltd Compounds, compositions and methods for treatment of eye disorders and skin diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9315856D0 (en) * 1993-07-30 1993-09-15 Wellcome Found Stabilized pharmaceutical
AUPN814496A0 (en) * 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
US6221917B1 (en) * 1997-12-30 2001-04-24 American Home Products Corporation Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
WO1999038504A1 (en) * 1998-01-29 1999-08-05 Sepracor Inc. Pharmaceutical uses of optically pure (-)-bupropion
CA2318921A1 (en) * 1998-01-29 1999-08-05 John R. Mccullough Pharmacological uses of optically pure (+)-bupropion
AU2483499A (en) * 1998-01-29 1999-08-16 Sepracor, Inc. Pharmaceutical uses of optically pure (+)-bupropion

Also Published As

Publication number Publication date
CA2307958A1 (en) 2000-11-10
EP1051971B1 (de) 2007-11-28
EP1051971A1 (de) 2000-11-15
US6312716B1 (en) 2001-11-06
JP2000327564A (ja) 2000-11-28

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Legal Events

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8332 No legal effect for de