DE60034678T2 - Logarithmischer lichtverstärker zum gebrauch mit photorezeptor basierenden implantierten retinalprothesen - Google Patents
Logarithmischer lichtverstärker zum gebrauch mit photorezeptor basierenden implantierten retinalprothesen Download PDFInfo
- Publication number
- DE60034678T2 DE60034678T2 DE60034678T DE60034678T DE60034678T2 DE 60034678 T2 DE60034678 T2 DE 60034678T2 DE 60034678 T DE60034678 T DE 60034678T DE 60034678 T DE60034678 T DE 60034678T DE 60034678 T2 DE60034678 T2 DE 60034678T2
- Authority
- DE
- Germany
- Prior art keywords
- image
- eye
- retinal
- light
- photoreceptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000002207 retinal effect Effects 0.000 title claims abstract description 60
- 108091008695 photoreceptors Proteins 0.000 claims abstract description 54
- 230000003287 optical effect Effects 0.000 claims abstract description 10
- 210000001525 retina Anatomy 0.000 claims abstract description 6
- 230000000007 visual effect Effects 0.000 claims description 8
- 210000005036 nerve Anatomy 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 5
- 230000006835 compression Effects 0.000 claims description 3
- 238000007906 compression Methods 0.000 claims description 3
- 108020003175 receptors Proteins 0.000 claims description 2
- 230000007383 nerve stimulation Effects 0.000 claims 1
- 230000000638 stimulation Effects 0.000 abstract description 34
- 230000003321 amplification Effects 0.000 abstract description 9
- 238000003199 nucleic acid amplification method Methods 0.000 abstract description 9
- 230000004456 color vision Effects 0.000 abstract description 8
- 239000003086 colorant Substances 0.000 abstract description 3
- 230000004438 eyesight Effects 0.000 abstract description 3
- 238000002347 injection Methods 0.000 abstract description 3
- 239000007924 injection Substances 0.000 abstract description 3
- 201000004569 Blindness Diseases 0.000 abstract description 2
- 238000003384 imaging method Methods 0.000 abstract description 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000002051 biphasic effect Effects 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 39
- 239000007943 implant Substances 0.000 description 16
- 230000006870 function Effects 0.000 description 8
- 239000012530 fluid Substances 0.000 description 7
- 238000012545 processing Methods 0.000 description 7
- 210000001747 pupil Anatomy 0.000 description 6
- 238000011084 recovery Methods 0.000 description 6
- 230000006978 adaptation Effects 0.000 description 5
- 230000005540 biological transmission Effects 0.000 description 3
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- 206010047571 Visual impairment Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000013507 mapping Methods 0.000 description 2
- 210000001328 optic nerve Anatomy 0.000 description 2
- 238000002310 reflectometry Methods 0.000 description 2
- 239000000829 suppository Substances 0.000 description 2
- 208000029257 vision disease Diseases 0.000 description 2
- 230000004393 visual impairment Effects 0.000 description 2
- 201000007737 Retinal degeneration Diseases 0.000 description 1
- 206010057430 Retinal injury Diseases 0.000 description 1
- 208000004350 Strabismus Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000012884 algebraic function Methods 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 210000003986 cell retinal photoreceptor Anatomy 0.000 description 1
- 230000007248 cellular mechanism Effects 0.000 description 1
- 239000002800 charge carrier Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000013479 data entry Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
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- 239000003623 enhancer Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 230000008447 perception Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000010363 phase shift Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000004258 retinal degeneration Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/08—Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Prostheses (AREA)
- Eye Examination Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12587499P | 1999-03-24 | 1999-03-24 | |
| US125874P | 1999-03-24 | ||
| PCT/US2000/005753 WO2000056244A2 (en) | 1999-03-24 | 2000-03-03 | Logarithmic light intensifier for use with photoreceptor-based implanted retinal prosthetics and those prosthetics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60034678D1 DE60034678D1 (de) | 2007-06-14 |
| DE60034678T2 true DE60034678T2 (de) | 2008-01-17 |
Family
ID=34421214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60034678T Expired - Fee Related DE60034678T2 (de) | 1999-03-24 | 2000-03-03 | Logarithmischer lichtverstärker zum gebrauch mit photorezeptor basierenden implantierten retinalprothesen |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US6507758B1 (https=) |
| EP (1) | EP1194083B1 (https=) |
| JP (1) | JP4384363B2 (https=) |
| AT (1) | ATE361041T1 (https=) |
| AU (1) | AU780183B2 (https=) |
| DE (1) | DE60034678T2 (https=) |
| WO (1) | WO2000056244A2 (https=) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6507758B1 (en) * | 1999-03-24 | 2003-01-14 | Second Sight, Llc | Logarithmic light intensifier for use with photoreceptor-based implanted retinal prosthetics and those prosthetics |
| WO2000056393A1 (en) * | 1999-03-24 | 2000-09-28 | Second Sight, Llc | Retinal color prosthesis for color sight restoration |
| US7103416B2 (en) * | 2001-01-16 | 2006-09-05 | Second Sight Medical Products, Inc. | Visual prosthesis including enhanced receiving and stimulating portion |
| WO2003015863A2 (en) * | 2001-08-17 | 2003-02-27 | Advanced Bionics Corporation | Gradual recruitment of muscle/neural excitable tissue using high-rate electrical stimulation parameters |
| US6976998B2 (en) * | 2002-01-17 | 2005-12-20 | Massachusetts Institute Of Technology | Minimally invasive retinal prosthesis |
| US7127301B1 (en) | 2003-04-28 | 2006-10-24 | Sandia Corporation | Flexible retinal electrode array |
| US7321796B2 (en) * | 2003-05-01 | 2008-01-22 | California Institute Of Technology | Method and system for training a visual prosthesis |
| US8260428B2 (en) * | 2003-05-01 | 2012-09-04 | California Institute Of Technology | Method and system for training a visual prosthesis |
| DE10329615A1 (de) * | 2003-06-23 | 2005-03-03 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Aktives Retina-Implantat mit einer Vielzahl von Bildelementen |
| US7311723B2 (en) * | 2003-07-11 | 2007-12-25 | University Of Washington | Scanning laser device and methods of use |
| US20050090875A1 (en) * | 2003-09-10 | 2005-04-28 | Palanker Daniel V. | Optical projection and tracking system for retinal prosthesis |
| GB2415631A (en) * | 2004-07-03 | 2006-01-04 | Martin Lister | Artificial eye with light sensitive LDRs |
| JP4310247B2 (ja) * | 2004-07-23 | 2009-08-05 | 株式会社ニデック | 視覚再生補助装置 |
| US8401212B2 (en) | 2007-10-12 | 2013-03-19 | Earlens Corporation | Multifunction system and method for integrated hearing and communication with noise cancellation and feedback management |
| US8103352B2 (en) * | 2004-12-03 | 2012-01-24 | Second Sight Medical Products, Inc. | Mimicking neural coding in retinal ganglion cells with short pulse electrical stimulation |
| US7571004B2 (en) | 2005-01-26 | 2009-08-04 | Second Sight Medical Products, Inc. | Neural stimulation for increased persistence |
| WO2006089155A2 (en) * | 2005-02-16 | 2006-08-24 | Second Sight Medical Products, Inc. | Fitting of brightness in a visual prosthesis |
| DE102005032989A1 (de) * | 2005-07-14 | 2007-01-25 | Imi Intelligent Medical Implants Ag | Extraokulares Epiretinal-Implantat |
| EP1951366B1 (en) * | 2005-09-16 | 2013-04-17 | Second Sight Medical Products, Inc. | Neural stimulation for increased contrast |
| US8709078B1 (en) * | 2011-08-03 | 2014-04-29 | Lockheed Martin Corporation | Ocular implant with substantially constant retinal spacing for transmission of nerve-stimulation light |
| US7877866B1 (en) * | 2005-10-26 | 2011-02-01 | Second Sight Medical Products, Inc. | Flexible circuit electrode array and method of manufacturing the same |
| US8271091B2 (en) * | 2006-04-28 | 2012-09-18 | Second Sight Medical Products, Inc. | Visual prosthesis fitting |
| EP2032205A2 (en) * | 2006-06-16 | 2009-03-11 | Second Sight Medical Products, Inc. | A method for electrical stimulation of human retina using pulse trains |
| US8457754B2 (en) * | 2006-06-16 | 2013-06-04 | Second Sight Medical Products, Inc. | Apparatus and method for electrical stimulation of human neurons |
| US8311634B2 (en) * | 2006-06-16 | 2012-11-13 | Second Sight Medical Products Inc. | Apparatus and method for electrical stimulation of human retina |
| GB0612242D0 (en) * | 2006-06-21 | 2006-08-02 | Imp Innovations Ltd | Retinal prosthetic devices |
| US9254385B2 (en) * | 2008-05-14 | 2016-02-09 | Second Sight Medical Products, Inc. | Visual prosthesis for phosphene shape control |
| WO2009155358A1 (en) | 2008-06-17 | 2009-12-23 | Earlens Corporation | Optical electro-mechanical hearing devices with separate power and signal components |
| WO2010017448A1 (en) * | 2008-08-07 | 2010-02-11 | Massachusetts Institute Of Technology | Coding for visual prostheses |
| EP3509324B1 (en) | 2008-09-22 | 2023-08-16 | Earlens Corporation | Balanced armature devices and methods for hearing |
| US8706243B2 (en) | 2009-02-09 | 2014-04-22 | Rainbow Medical Ltd. | Retinal prosthesis techniques |
| US8442641B2 (en) * | 2010-08-06 | 2013-05-14 | Nano-Retina, Inc. | Retinal prosthesis techniques |
| US8150526B2 (en) | 2009-02-09 | 2012-04-03 | Nano-Retina, Inc. | Retinal prosthesis |
| US8718784B2 (en) * | 2010-01-14 | 2014-05-06 | Nano-Retina, Inc. | Penetrating electrodes for retinal stimulation |
| US8428740B2 (en) | 2010-08-06 | 2013-04-23 | Nano-Retina, Inc. | Retinal prosthesis techniques |
| US9544700B2 (en) | 2009-06-15 | 2017-01-10 | Earlens Corporation | Optically coupled active ossicular replacement prosthesis |
| CN102598713A (zh) | 2009-06-18 | 2012-07-18 | 音束有限责任公司 | 用于听力系统的耳膜可植入装置及方法 |
| CN102640435B (zh) * | 2009-06-18 | 2016-11-16 | 伊尔莱茵斯公司 | 光学耦合的耳蜗植入系统及方法 |
| BRPI1016075A2 (pt) | 2009-06-22 | 2016-05-10 | SoundBeam LLC | dispositivo para transmitir som para um ouvido de um usuário e métodos associados. |
| US8845705B2 (en) | 2009-06-24 | 2014-09-30 | Earlens Corporation | Optical cochlear stimulation devices and methods |
| EP3758394A1 (en) | 2010-12-20 | 2020-12-30 | Earlens Corporation | Anatomically customized ear canal hearing apparatus |
| US8571669B2 (en) | 2011-02-24 | 2013-10-29 | Nano-Retina, Inc. | Retinal prosthesis with efficient processing circuits |
| FR2975251B1 (fr) * | 2011-05-12 | 2015-12-04 | Univ Pierre Et Marie Curie Paris 6 | Procede et dispositif de commande d'un dispositif d'aide a la vision |
| US8715345B2 (en) * | 2011-05-23 | 2014-05-06 | California Institute Of Technology | Accommodating intraocular lens |
| US8771347B2 (en) * | 2011-05-23 | 2014-07-08 | California Institute Of Technology | Accommodating intraocular lens |
| CN102283742B (zh) * | 2011-08-15 | 2013-09-11 | 重庆大学 | 一种光刺激视网膜假体修复装置 |
| US10376301B2 (en) | 2011-09-28 | 2019-08-13 | Covidien Lp | Logarithmic amplifier, electrosurgical generator including same, and method of controlling electrosurgical generator using same |
| WO2013067538A1 (en) | 2011-11-04 | 2013-05-10 | Nevro Corporation | Medical device communication and charding assemblies for use with implantable signal generators |
| US10121533B2 (en) | 2012-11-21 | 2018-11-06 | Nano-Retina, Inc. | Techniques for data retention in memory cells during power interruption |
| US9720477B2 (en) | 2012-11-21 | 2017-08-01 | Nano-Retina, Inc. | Weak power supply operation and control |
| US9959674B2 (en) * | 2013-02-26 | 2018-05-01 | Qualcomm Incorporated | Directional and X-ray view techniques for navigation using a mobile device |
| US9370417B2 (en) | 2013-03-14 | 2016-06-21 | Nano-Retina, Inc. | Foveated retinal prosthesis |
| US9474902B2 (en) | 2013-12-31 | 2016-10-25 | Nano Retina Ltd. | Wearable apparatus for delivery of power to a retinal prosthesis |
| US9331791B2 (en) | 2014-01-21 | 2016-05-03 | Nano Retina Ltd. | Transfer of power and data |
| US10034103B2 (en) | 2014-03-18 | 2018-07-24 | Earlens Corporation | High fidelity and reduced feedback contact hearing apparatus and methods |
| DK3169396T3 (da) | 2014-07-14 | 2021-06-28 | Earlens Corp | Glidende forspænding og peak-begrænsning for optiske høreapparater |
| US9924276B2 (en) | 2014-11-26 | 2018-03-20 | Earlens Corporation | Adjustable venting for hearing instruments |
| TWI569817B (zh) * | 2015-07-08 | 2017-02-11 | 國立交通大學 | 人工視網膜系統、眼外光學裝置及眼內植入晶片 |
| DK3888564T3 (da) | 2015-10-02 | 2025-07-14 | Earlens Corp | Indretning til tilpasset afgivelse af medicin i øregangen |
| US11350226B2 (en) | 2015-12-30 | 2022-05-31 | Earlens Corporation | Charging protocol for rechargeable hearing systems |
| WO2017116791A1 (en) | 2015-12-30 | 2017-07-06 | Earlens Corporation | Light based hearing systems, apparatus and methods |
| US10492010B2 (en) | 2015-12-30 | 2019-11-26 | Earlens Corporations | Damping in contact hearing systems |
| EP3500218B1 (en) | 2016-06-23 | 2021-10-13 | Frank H. Boehm | Minimally invasive surgical systems for fusion of the sacroiliac joint |
| CN112738700A (zh) | 2016-09-09 | 2021-04-30 | 伊尔兰斯公司 | 智能镜系统和方法 |
| WO2018059568A1 (zh) * | 2016-09-30 | 2018-04-05 | 深圳硅基仿生科技有限公司 | 用于神经刺激的脉冲电流产生电路、电荷补偿电路和方法及植入式视网膜电刺激器 |
| WO2018093733A1 (en) | 2016-11-15 | 2018-05-24 | Earlens Corporation | Improved impression procedure |
| US11638833B2 (en) | 2017-08-02 | 2023-05-02 | Multi Radiance Medical | Reducing light polution in photobiomodulation therapy of a patients eye |
| WO2019028222A1 (en) | 2017-08-02 | 2019-02-07 | Multi Radiance Medical | SYSTEM AND METHOD FOR DIRECTING LIGHT IN THE EYE OF A PATIENT |
| WO2019173470A1 (en) | 2018-03-07 | 2019-09-12 | Earlens Corporation | Contact hearing device and retention structure materials |
| WO2019199680A1 (en) | 2018-04-09 | 2019-10-17 | Earlens Corporation | Dynamic filter |
| AU2019261983B2 (en) | 2018-05-01 | 2024-12-05 | Nevro Corp. | A 2.4 GHz radio antenna for implanted medical devices, and associated systems and methods |
| WO2020192943A1 (en) * | 2019-03-28 | 2020-10-01 | Pixium Vision Sa | Method and device for projecting a pattern of interest on a modified retinal area of a human eye |
| CN116490154A (zh) * | 2020-09-24 | 2023-07-25 | 南加利福尼亚大学 | 用于恢复盲人颜色感知的系统和方法 |
| EP4231893A1 (en) * | 2020-09-29 | 2023-08-30 | Era Ophthalmica S.R.L. | Device for retinal neuromodulation therapy and extrafoveal reading in subjects affected by visual impairment |
| CN112717282B (zh) * | 2021-01-14 | 2023-01-10 | 重庆翰恒医疗科技有限公司 | 一种光诊疗装置及全自动光诊疗系统 |
| CN113258130B (zh) * | 2021-04-27 | 2023-01-03 | 燕山大学 | 非晶卤化物固体电解质及制备和在全固态电池中的应用 |
| KR102564879B1 (ko) * | 2021-06-02 | 2023-08-07 | 아주대학교산학협력단 | 2상 자극 시간 조절 방식의 인공망막 장치 및 그의 구동 방법 |
| US12295831B2 (en) | 2023-10-23 | 2025-05-13 | California Institute Of Technology | Liquid accommodating intraocular lens with an asymmetric chamber |
| CN119570731B (zh) * | 2024-12-10 | 2025-07-22 | 天津大学 | 一种在体外重建眼脑视觉通路模型的方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3449768A (en) * | 1966-12-27 | 1969-06-17 | James H Doyle | Artificial sense organ |
| GB1286316A (en) * | 1969-11-13 | 1972-08-23 | Hermann Mengeler | Method and apparatus for transmitting optical impressions upon the visual regions of the human cerebral cortex |
| DE2948266A1 (de) * | 1979-11-30 | 1981-06-19 | geb. Lehrmund Margot 8000 München Stover | Sehgeraet |
| US4611596A (en) * | 1980-10-14 | 1986-09-16 | Purdue Research Foundation | Sensory prostheses |
| US4628933A (en) | 1985-07-23 | 1986-12-16 | Michelson Robin P | Method and apparatus for visual prosthesis |
| US4677989A (en) * | 1986-02-06 | 1987-07-07 | Eic Laboratories, Inc. | Iridium oxide coated electrodes for neural stimulation |
| US5016633A (en) | 1989-08-08 | 1991-05-21 | Chow Alan Y | Artificial retina device |
| US5109844A (en) * | 1990-10-11 | 1992-05-05 | Duke University | Retinal microstimulation |
| US5369415A (en) | 1992-06-29 | 1994-11-29 | Motorola, Inc. | Direct retinal scan display with planar imager |
| US5467104A (en) | 1992-10-22 | 1995-11-14 | Board Of Regents Of The University Of Washington | Virtual retinal display |
| US5556423A (en) | 1993-05-03 | 1996-09-17 | Alan Y. Chow | Independent photoelectric artificial retina device and method of using same |
| US5397350A (en) | 1993-05-03 | 1995-03-14 | Chow; Alan Y. | Independent photoelectric artificial retina device and method of using same |
| NZ310074A (en) * | 1995-06-06 | 1999-09-29 | Vincent Chow | Dual pin nip microphotodiode retinal implants |
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| US5935155A (en) | 1998-03-13 | 1999-08-10 | John Hopkins University, School Of Medicine | Visual prosthesis and method of using same |
| US6397350B1 (en) * | 1999-02-19 | 2002-05-28 | International Business Machines Corporation | Method of providing direct data processing access using a queued direct input-output device |
| US6507758B1 (en) * | 1999-03-24 | 2003-01-14 | Second Sight, Llc | Logarithmic light intensifier for use with photoreceptor-based implanted retinal prosthetics and those prosthetics |
| US6389317B1 (en) * | 2000-03-31 | 2002-05-14 | Optobionics Corporation | Multi-phasic microphotodetector retinal implant with variable voltage and current capability |
-
2000
- 2000-02-29 US US09/515,383 patent/US6507758B1/en not_active Expired - Lifetime
- 2000-03-03 JP JP2000606153A patent/JP4384363B2/ja not_active Expired - Fee Related
- 2000-03-03 EP EP00917743A patent/EP1194083B1/en not_active Expired - Lifetime
- 2000-03-03 DE DE60034678T patent/DE60034678T2/de not_active Expired - Fee Related
- 2000-03-03 AU AU38671/00A patent/AU780183B2/en not_active Ceased
- 2000-03-03 WO PCT/US2000/005753 patent/WO2000056244A2/en not_active Ceased
- 2000-03-03 AT AT00917743T patent/ATE361041T1/de not_active IP Right Cessation
-
2002
- 2002-11-26 US US10/304,815 patent/US7133724B2/en not_active Expired - Lifetime
-
2006
- 2006-09-14 US US11/522,001 patent/US7539544B2/en not_active Expired - Fee Related
-
2009
- 2009-04-16 US US12/425,236 patent/US8046078B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20070016294A1 (en) | 2007-01-18 |
| AU3867100A (en) | 2000-10-09 |
| US20090204212A1 (en) | 2009-08-13 |
| EP1194083A2 (en) | 2002-04-10 |
| AU780183B2 (en) | 2005-03-03 |
| US7133724B2 (en) | 2006-11-07 |
| WO2000056244A3 (en) | 2002-01-24 |
| US7539544B2 (en) | 2009-05-26 |
| US20030181957A1 (en) | 2003-09-25 |
| ATE361041T1 (de) | 2007-05-15 |
| JP4384363B2 (ja) | 2009-12-16 |
| EP1194083B1 (en) | 2007-05-02 |
| US6507758B1 (en) | 2003-01-14 |
| DE60034678D1 (de) | 2007-06-14 |
| WO2000056244A2 (en) | 2000-09-28 |
| US8046078B2 (en) | 2011-10-25 |
| EP1194083A4 (en) | 2005-02-02 |
| JP2002538936A (ja) | 2002-11-19 |
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