DE60033291D1 - Multi-komponenten impfstoff zum schutz vor krankheiten die durch haemophilus influenza und moxarella catarrhalis ausgelöst werden - Google Patents
Multi-komponenten impfstoff zum schutz vor krankheiten die durch haemophilus influenza und moxarella catarrhalis ausgelöst werdenInfo
- Publication number
- DE60033291D1 DE60033291D1 DE60033291T DE60033291T DE60033291D1 DE 60033291 D1 DE60033291 D1 DE 60033291D1 DE 60033291 T DE60033291 T DE 60033291T DE 60033291 T DE60033291 T DE 60033291T DE 60033291 D1 DE60033291 D1 DE 60033291D1
- Authority
- DE
- Germany
- Prior art keywords
- antigens
- antigen
- component
- moraxella catarrhalis
- haemophilus influenzae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000606768 Haemophilus influenzae Species 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 6
- 102000036639 antigens Human genes 0.000 abstract 6
- 108091007433 antigens Proteins 0.000 abstract 6
- 241000588655 Moraxella catarrhalis Species 0.000 abstract 3
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 3
- 230000002163 immunogen Effects 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 abstract 2
- 241000991587 Enterovirus C Species 0.000 abstract 1
- 241000606790 Haemophilus Species 0.000 abstract 1
- 101710116435 Outer membrane protein Proteins 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002797 proteolythic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
- A61K39/1045—Moraxella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/353,617 US6391313B1 (en) | 1999-07-15 | 1999-07-15 | Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis |
| US353617 | 1999-07-15 | ||
| PCT/CA2000/000811 WO2001005424A2 (en) | 1999-07-15 | 2000-07-11 | Multi-component vaccine to protect against disease caused by haemophilus influenzae and moraxella catarrhalis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60033291D1 true DE60033291D1 (de) | 2007-03-22 |
| DE60033291T2 DE60033291T2 (de) | 2007-07-05 |
Family
ID=23389874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60033291T Expired - Lifetime DE60033291T2 (de) | 1999-07-15 | 2000-07-11 | Multi-komponenten impfstoff zum schutz vor krankheiten die durch haemophilus influenza und moxarella catarrhalis ausgelöst werden |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6391313B1 (de) |
| EP (2) | EP1200122B1 (de) |
| AT (1) | ATE353223T1 (de) |
| AU (1) | AU767096B2 (de) |
| CA (1) | CA2378862C (de) |
| CY (1) | CY1107620T1 (de) |
| DE (1) | DE60033291T2 (de) |
| DK (1) | DK1200122T3 (de) |
| ES (1) | ES2280230T3 (de) |
| PT (1) | PT1200122E (de) |
| SI (1) | SI1200122T1 (de) |
| WO (1) | WO2001005424A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6440425B1 (en) * | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| NZ517235A (en) * | 1999-07-27 | 2004-01-30 | Aventis Pasteur | Recombinant high molecular weight major outer membrane protein of moraxella |
| SE0102410D0 (sv) | 2001-07-04 | 2001-07-04 | Arne Forsgren | Novel surface exposed immunoglobulin D-binding protein from moraxella catarrhalis |
| JP2011514881A (ja) | 2007-11-09 | 2011-05-12 | ザ ソルク インスティテュート フォー バイオロジカル スタディーズ | 免疫増強剤としてのｔａｍ受容体阻害剤の使用および免疫抑制剤としてのｔａｍ活性化剤の使用 |
| CN105175549B (zh) * | 2015-09-30 | 2019-08-16 | 康希诺生物股份公司 | 一种流感嗜血杆菌融合蛋白及其构建方法与应用 |
| CN110662557A (zh) * | 2017-03-31 | 2020-01-07 | 葛兰素史克知识产权开发有限公司 | 免疫原性组合物、用途和治疗方法 |
| WO2018178265A1 (en) * | 2017-03-31 | 2018-10-04 | Glaxosmithkline Intellectual Property Development Limited | Immunogenic composition, use and method of treatment |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4496538A (en) | 1982-07-06 | 1985-01-29 | Connaught Laboratories, Inc. | Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine |
| ATE195076T1 (de) * | 1989-03-09 | 2000-08-15 | American Cyanamid Co | Verfahren zur isolierung von haemopnilus influenzae protein-e |
| US5843463A (en) | 1990-12-21 | 1998-12-01 | Antexbiologics, Inc. | Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae |
| US5603938A (en) | 1992-03-16 | 1997-02-18 | St. Louis University | High molecular weight surface proteins of non-typeable haemophilus |
| AU696207B2 (en) * | 1993-03-16 | 1998-09-03 | St. Louis University | High molecular weight surface proteins of non-typeable haemophilus |
| US5977336A (en) | 1993-03-16 | 1999-11-02 | St. Louis University | High molecular weight surface proteins of non-typeable haemophilus |
| US5712118A (en) * | 1993-09-29 | 1998-01-27 | Research Foundation Of State University Of New York | Vaccine for branhamella catarrhalis |
| US5506139A (en) | 1994-07-21 | 1996-04-09 | Connaught Laboratories Limited | Analog of haemophilus Hin47 with reduced protease activity |
| US6764682B1 (en) | 1994-06-16 | 2004-07-20 | Aventis Pasteur Limited | Adjuvant compositions containing more than one adjuvant |
| BR9506272B8 (pt) | 1994-07-21 | 2014-08-05 | Connaught Lab | PROTEÍNA MUTANTE ISOLADA E PURIFICADA Hin47 DE Haemophilus influenzae, MOLÉCULA QUIMÉRICA, MOLÉCULA DE ÁCIDO NUCLÉICO, PLASMÍDEO RECOMBINANTE, CÉLULA E. coli TRANSFORMADA, COMPOSIÇÃO IMUNOGÊNICA, PROCESSO PARA DETERMINAR A PRESENÇA DE ANTICORPOS, ESPECIFICAMENTE REATIVOS COM A PROTEÍNA Hin47 NUMA AMOSTRA, PROCESSO PARA DETERMINAR A PRESENÇA DE PROTEÍNA Hin47 NUMA AMOSTRA E KIT DE DIAGNÓSTICO PARA DETERMINAR A PRESENÇA DE ANTICORPOS NUMA AMOSTRA ESPECIFICAMENTE REATIVA COM A PROTEÍNA Hin47. |
| US5646259A (en) | 1995-03-24 | 1997-07-08 | St. Louis University | DNA encoding haemophilus adhesion proteins |
| US6440425B1 (en) | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| US6335018B1 (en) | 1995-05-01 | 2002-01-01 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| JP2002509115A (ja) * | 1998-01-13 | 2002-03-26 | アメリカ合衆国 | 哺乳動物におけるモラクセラ（ブランハメラ）カタラリス感染の予防のためのリポオリゴ糖ベースのワクチン |
| US6974581B1 (en) * | 1998-12-15 | 2005-12-13 | Aventis Pasteur Limited | Multi-component vaccine comprising at least two antigens from haemophilus influenzae to protect against disease |
-
1999
- 1999-07-15 US US09/353,617 patent/US6391313B1/en not_active Expired - Lifetime
-
2000
- 2000-07-11 CA CA002378862A patent/CA2378862C/en not_active Expired - Fee Related
- 2000-07-11 SI SI200030936T patent/SI1200122T1/sl unknown
- 2000-07-11 DK DK00945494T patent/DK1200122T3/da active
- 2000-07-11 AU AU59586/00A patent/AU767096B2/en not_active Ceased
- 2000-07-11 ES ES00945494T patent/ES2280230T3/es not_active Expired - Lifetime
- 2000-07-11 WO PCT/CA2000/000811 patent/WO2001005424A2/en active IP Right Grant
- 2000-07-11 PT PT00945494T patent/PT1200122E/pt unknown
- 2000-07-11 EP EP00945494A patent/EP1200122B1/de not_active Revoked
- 2000-07-11 EP EP06076726A patent/EP1880734A3/de not_active Withdrawn
- 2000-07-11 AT AT00945494T patent/ATE353223T1/de active
- 2000-07-11 DE DE60033291T patent/DE60033291T2/de not_active Expired - Lifetime
-
2007
- 2007-04-23 CY CY20071100548T patent/CY1107620T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60033291T2 (de) | 2007-07-05 |
| EP1200122B1 (de) | 2007-02-07 |
| AU5958600A (en) | 2001-02-05 |
| CA2378862C (en) | 2005-05-10 |
| CY1107620T1 (el) | 2013-03-13 |
| ES2280230T3 (es) | 2007-09-16 |
| ATE353223T1 (de) | 2007-02-15 |
| US6391313B1 (en) | 2002-05-21 |
| DK1200122T3 (da) | 2007-06-04 |
| WO2001005424A3 (en) | 2001-08-02 |
| PT1200122E (pt) | 2007-05-31 |
| SI1200122T1 (sl) | 2007-08-31 |
| EP1200122A2 (de) | 2002-05-02 |
| WO2001005424A2 (en) | 2001-01-25 |
| AU767096B2 (en) | 2003-10-30 |
| EP1880734A3 (de) | 2008-06-25 |
| CA2378862A1 (en) | 2001-01-25 |
| EP1880734A2 (de) | 2008-01-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent |