CY1106252T1 - Εμβολιο πολλαπλων συστατικων που πepιλαμβανει τουλαχιστον δυο αντιγονα απο haemophilus influenzae για την προστασια εναντι νοσησης - Google Patents
Εμβολιο πολλαπλων συστατικων που πepιλαμβανει τουλαχιστον δυο αντιγονα απο haemophilus influenzae για την προστασια εναντι νοσησηςInfo
- Publication number
- CY1106252T1 CY1106252T1 CY20061101690T CY061101690T CY1106252T1 CY 1106252 T1 CY1106252 T1 CY 1106252T1 CY 20061101690 T CY20061101690 T CY 20061101690T CY 061101690 T CY061101690 T CY 061101690T CY 1106252 T1 CY1106252 T1 CY 1106252T1
- Authority
- CY
- Cyprus
- Prior art keywords
- haemophilus influenzae
- antigens
- attaching
- protection against
- against disease
- Prior art date
Links
- 241000606768 Haemophilus influenzae Species 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 229940047650 haemophilus influenzae Drugs 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 206010061190 Haemophilus infection Diseases 0.000 abstract 1
- 229940124865 Haemophilus vaccine Drugs 0.000 abstract 1
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 abstract 1
- 230000005745 host immune response Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 230000002797 proteolythic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Ανοσογόνος σύνθεση πολλαπλών συστατικών επιφέρει προστασία σε ανοσοποιημένο ξενιστή έναντι λοίμωξης προκαλούμενης από Haemophilus influenzae. Τέτοια σύνθεση περιλαμβάνει τουλάχιστον δύο διαφορετικά αντιγόνα του Haemophilus influenzae, ένα των οποίων είναι κάποια προσκολλησίνη. Πρωτεΐνες υψηλού μοριακού βάρους (HMW) κάποιου μη τυποποιούμενου Haemophilus influenzae ενισχύουν την ανοσοαπόκριση σε ξενιστή έναντι κάποιου μη πρωτεολυτικού αναλόγου της πρωτεΐνης Hin47 σε τέτοιες ανοσογόνες συνθέσεις με το ένα συστατικό να μη μειώνει την ανοσογονικότητα του άλλου. Το εμβόλιο Haemophilus μπορεί να συνδυαστεί με εμβόλια DTP-συστατικών για την παροχή εμβολίων πολυσθενών συστατικών χωρίς εξασθένηση των ανοσογονικών ιδιοτήτων των άλλων αντιγόνων.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/210,995 US6974581B1 (en) | 1998-12-15 | 1998-12-15 | Multi-component vaccine comprising at least two antigens from haemophilus influenzae to protect against disease |
PCT/CA1999/001189 WO2000035477A2 (en) | 1998-12-15 | 1999-12-15 | Multi-component vaccine comprising at least two antigens from haemophilus influenzae |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106252T1 true CY1106252T1 (el) | 2011-06-08 |
Family
ID=22785184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101690T CY1106252T1 (el) | 1998-12-15 | 2006-11-21 | Εμβολιο πολλαπλων συστατικων που πepιλαμβανει τουλαχιστον δυο αντιγονα απο haemophilus influenzae για την προστασια εναντι νοσησης |
Country Status (14)
Country | Link |
---|---|
US (3) | US6974581B1 (el) |
EP (1) | EP1140158B2 (el) |
JP (1) | JP4105393B2 (el) |
AT (1) | ATE339221T1 (el) |
AU (1) | AU772882B2 (el) |
CA (1) | CA2355466C (el) |
CY (1) | CY1106252T1 (el) |
DE (1) | DE69933237T3 (el) |
DK (1) | DK1140158T4 (el) |
ES (1) | ES2272086T5 (el) |
NZ (1) | NZ512679A (el) |
PT (1) | PT1140158E (el) |
SI (1) | SI1140158T2 (el) |
WO (1) | WO2000035477A2 (el) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6974581B1 (en) * | 1998-12-15 | 2005-12-13 | Aventis Pasteur Limited | Multi-component vaccine comprising at least two antigens from haemophilus influenzae to protect against disease |
US6342232B1 (en) * | 1999-03-03 | 2002-01-29 | Aventis Pasteur Limited | Multi-component vaccine comprising at least three antigens to protect against disease cased by Haemophilus influenzae |
US7785609B1 (en) | 1999-03-16 | 2010-08-31 | Sanofi Pasteur Limited | Recombinant Haemophilus influenzae adhesin proteins |
US6391313B1 (en) * | 1999-07-15 | 2002-05-21 | Aventis Pasteur Limited | Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis |
US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
EP2773056B1 (en) | 2013-03-01 | 2018-05-09 | ADVA Optical Networking SE | A method for tuning a tunable optical transmitter in an optical WDM transmission system and corresponding optical WDM transmission system |
JP7382788B2 (ja) | 2019-10-29 | 2023-11-17 | 株式会社ノダ | 框組み建具 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US320942A (en) * | 1885-06-30 | Stone-dressing machine | ||
US6103243A (en) * | 1985-05-15 | 2000-08-15 | Biotechnology Australia Pty, Ltd | Oral vaccines |
IT1187753B (it) * | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
US5843463A (en) * | 1990-12-21 | 1998-12-01 | Antexbiologics, Inc. | Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae |
GB9205704D0 (en) * | 1992-03-16 | 1992-04-29 | Connaught Lab | High molecular weight membrane proteins of non-typeable haemophilus |
ATE168271T1 (de) * | 1992-05-23 | 1998-08-15 | Smithkline Beecham Biolog | Kombinierte impfstoffe, die hepatitis b oberfläche antigen und andere antigenen enthalten |
US5977336A (en) * | 1993-03-16 | 1999-11-02 | St. Louis University | High molecular weight surface proteins of non-typeable haemophilus |
US5770213A (en) * | 1994-05-05 | 1998-06-23 | American Cyanamid Company | Purified nontypable haemophilus influenzae P5 protein as a vaccine for nontypable haemophilus influenzae infection |
US5506139A (en) * | 1994-07-21 | 1996-04-09 | Connaught Laboratories Limited | Analog of haemophilus Hin47 with reduced protease activity |
BR9506272B8 (pt) * | 1994-07-21 | 2014-08-05 | Connaught Lab | PROTEÍNA MUTANTE ISOLADA E PURIFICADA Hin47 DE Haemophilus influenzae, MOLÉCULA QUIMÉRICA, MOLÉCULA DE ÁCIDO NUCLÉICO, PLASMÍDEO RECOMBINANTE, CÉLULA E. coli TRANSFORMADA, COMPOSIÇÃO IMUNOGÊNICA, PROCESSO PARA DETERMINAR A PRESENÇA DE ANTICORPOS, ESPECIFICAMENTE REATIVOS COM A PROTEÍNA Hin47 NUMA AMOSTRA, PROCESSO PARA DETERMINAR A PRESENÇA DE PROTEÍNA Hin47 NUMA AMOSTRA E KIT DE DIAGNÓSTICO PARA DETERMINAR A PRESENÇA DE ANTICORPOS NUMA AMOSTRA ESPECIFICAMENTE REATIVA COM A PROTEÍNA Hin47. |
FR2734484B1 (fr) * | 1995-05-24 | 1997-06-27 | Pasteur Merieux Serums Vacc | Composition vaccinale liquide et procede de fabrication |
US5750116A (en) * | 1995-06-02 | 1998-05-12 | Bactex, Inc. | Haemophilus influenzae pilus vaccines |
US6974581B1 (en) * | 1998-12-15 | 2005-12-13 | Aventis Pasteur Limited | Multi-component vaccine comprising at least two antigens from haemophilus influenzae to protect against disease |
-
1998
- 1998-12-15 US US09/210,995 patent/US6974581B1/en not_active Expired - Fee Related
-
1999
- 1999-12-15 PT PT99957822T patent/PT1140158E/pt unknown
- 1999-12-15 SI SI9930932T patent/SI1140158T2/sl unknown
- 1999-12-15 DE DE69933237T patent/DE69933237T3/de not_active Expired - Lifetime
- 1999-12-15 JP JP2000587796A patent/JP4105393B2/ja not_active Expired - Fee Related
- 1999-12-15 ES ES99957822T patent/ES2272086T5/es not_active Expired - Lifetime
- 1999-12-15 WO PCT/CA1999/001189 patent/WO2000035477A2/en active IP Right Grant
- 1999-12-15 CA CA002355466A patent/CA2355466C/en not_active Expired - Fee Related
- 1999-12-15 DK DK99957822.2T patent/DK1140158T4/da active
- 1999-12-15 AU AU15439/00A patent/AU772882B2/en not_active Ceased
- 1999-12-15 NZ NZ512679A patent/NZ512679A/en not_active IP Right Cessation
- 1999-12-15 EP EP99957822A patent/EP1140158B2/en not_active Expired - Lifetime
- 1999-12-15 AT AT99957822T patent/ATE339221T1/de active
-
2004
- 2004-09-30 US US10/955,055 patent/US20050118189A1/en not_active Abandoned
-
2006
- 2006-11-21 CY CY20061101690T patent/CY1106252T1/el unknown
-
2007
- 2007-10-23 US US11/975,956 patent/US20080286303A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69933237T2 (de) | 2007-04-12 |
EP1140158B1 (en) | 2006-09-13 |
PT1140158E (pt) | 2007-01-31 |
DE69933237D1 (de) | 2006-10-26 |
WO2000035477A3 (en) | 2000-10-26 |
DE69933237T3 (de) | 2011-03-03 |
SI1140158T2 (sl) | 2010-10-29 |
DK1140158T4 (da) | 2010-08-23 |
CA2355466A1 (en) | 2000-06-22 |
US6974581B1 (en) | 2005-12-13 |
EP1140158A2 (en) | 2001-10-10 |
AU1543900A (en) | 2000-07-03 |
SI1140158T1 (sl) | 2007-02-28 |
ES2272086T5 (es) | 2010-11-29 |
JP4105393B2 (ja) | 2008-06-25 |
JP2002532433A (ja) | 2002-10-02 |
ATE339221T1 (de) | 2006-10-15 |
US20080286303A1 (en) | 2008-11-20 |
CA2355466C (en) | 2009-09-08 |
ES2272086T3 (es) | 2007-04-16 |
DK1140158T3 (da) | 2007-01-22 |
EP1140158B2 (en) | 2010-07-28 |
US20050118189A1 (en) | 2005-06-02 |
AU772882B2 (en) | 2004-05-13 |
NZ512679A (en) | 2003-08-29 |
WO2000035477A2 (en) | 2000-06-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1106252T1 (el) | Εμβολιο πολλαπλων συστατικων που πepιλαμβανει τουλαχιστον δυο αντιγονα απο haemophilus influenzae για την προστασια εναντι νοσησης | |
KR920014829A (ko) | 뉴모코커스 다당류 결합체 백신 | |
BR9906927A (pt) | Proteìnas de neisseria meningitidis | |
BRPI0707154B8 (pt) | composição de vacina | |
BR9306820A (pt) | Conjugado de um antígeno fracamente imunogênico e um veículo peptideo sintetico vacina processos para melhorar a imunogenicidade de uma molecula de antigeno fracamente imunogenico e para imunizar um hospedeiro mamífero | |
DK0427347T3 (da) | Syntetiske peptider, der kan anvendes som universelle bærere til fremstilling af immunogene konjugater, og anvendelse deraf til udvikling af syntetiske vacciner | |
IS4518A (is) | Nýtt lyfjaform fyrir bóluefni | |
DK0778781T3 (da) | Pneumokok-polysaccharid-rekombinant pneumolysin-konjugat-vacciner til immunisering mod pneumokokinfektioner | |
WO1998046725A3 (en) | Attenuated, invasive vaccines against fish pathogens | |
CY1105010T1 (el) | Πεπτιδια που λαμβανονται απο τη συνδεση (g) πρωτεϊνης του αναπνευστικου συνκυτιακου ιου | |
WO2002072036A3 (en) | Compositions and methods comprising west nile virus polypeptides | |
WO2010141312A3 (en) | Flagellin fusion proteins and conjugates comprising pneumococcus antigens and methods of using the same | |
CY1107620T1 (el) | Πολυ-συστατικο εμβολιο για την προστασια εναντι της παθησης που προκαλειται απο haemophilus influenzae and moraxella catarrhalis | |
WO2003065973A3 (en) | Multivalent streptococcal vaccine compositions and methods for use | |
ATE302016T1 (de) | Peptide, verwendet als träger in immunogenen konstrukten, die in der entwicklung synthetischer impfstoffe geeignet sind | |
ATE105189T1 (de) | Haemophilus influenzae typ b polysaccharidaussermembranprotein-konjugat als impfstoff. | |
BR9709993A (pt) | Vacina preparação de vacina composição processo para produção de uma preparação imugênica e preparação imugênica | |
WO2002009749A3 (en) | Respiratory syncytial virus vaccine | |
WO2000051633A3 (en) | MULTI-COMPONENT VACCINE COMPRISING AT LEAST THREE ANTIGENS TO PROTECT AGAINST DISEASE CAUSED BY $i(HAEMOPHILUS INFLUENZAE) | |
ATE471156T1 (de) | Antigene zusammensetzungen zur immunisierung nichtmenschlicher säuger gegen streptococcus equi | |
DK1005487T3 (da) | Ydre 74 kD-membranprotein fra Moraxella catarrhalis | |
WO2002004497A3 (en) | Multiple antigenic peptides immunogenic against streptococcus pneumoniae | |
PL331792A1 (en) | Aviadenovirus, nucleic acid sequence encoding an antigen determinant, host cell transformed by such sequence, antibody or immune serum reacting with such antigen determinant and vaccine against diseases associated with a novel adenovirus | |
EP1535928A3 (en) | Omp85 proteins of Neisseria gonorrhoeae and Neisseria meningitidis, compositions containing same and methods of use thereof | |
RAHMAN et al. | CROSS-PROTECTION INDUCED BY CROSS-REACTIVE ANTIGEN AGAINST FASCIOLA GlGANTlCA AND TRICHINEL LA SPlRA LlS INFECTIONS |