DE60028563D1 - Aryl-chloralkyl harnstoffe - Google Patents

Aryl-chloralkyl harnstoffe

Info

Publication number
DE60028563D1
DE60028563D1 DE60028563T DE60028563T DE60028563D1 DE 60028563 D1 DE60028563 D1 DE 60028563D1 DE 60028563 T DE60028563 T DE 60028563T DE 60028563 T DE60028563 T DE 60028563T DE 60028563 D1 DE60028563 D1 DE 60028563D1
Authority
DE
Germany
Prior art keywords
alkyl
halide
derivatives
cycloalkyl
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60028563T
Other languages
English (en)
Other versions
DE60028563T2 (de
Inventor
C Gaudreault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOVAR
Original Assignee
SOVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOVAR filed Critical SOVAR
Application granted granted Critical
Publication of DE60028563D1 publication Critical patent/DE60028563D1/de
Publication of DE60028563T2 publication Critical patent/DE60028563T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE60028563T 1999-04-12 2000-04-12 Aryl-chloralkylharnstoffe Expired - Fee Related DE60028563T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA2268588 1999-04-12
CA002268588A CA2268588A1 (en) 1999-04-12 1999-04-12 Novel aryl-chloro-ethyl ureas
PCT/CA2000/000413 WO2000061546A2 (en) 1999-04-12 2000-04-12 Novel aryl-chloro-ethyl ureas

Publications (2)

Publication Number Publication Date
DE60028563D1 true DE60028563D1 (de) 2006-07-20
DE60028563T2 DE60028563T2 (de) 2006-11-09

Family

ID=4163454

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60028563T Expired - Fee Related DE60028563T2 (de) 1999-04-12 2000-04-12 Aryl-chloralkylharnstoffe

Country Status (10)

Country Link
US (1) US6686394B1 (de)
EP (1) EP1169303B1 (de)
JP (1) JP2002541240A (de)
AT (1) ATE312075T1 (de)
AU (1) AU778391B2 (de)
BR (1) BR0010615A (de)
CA (1) CA2268588A1 (de)
DE (1) DE60028563T2 (de)
MX (1) MXPA01010311A (de)
WO (1) WO2000061546A2 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61191667A (ja) 1985-02-21 1986-08-26 Tokuyama Soda Co Ltd 尿素化合物
CA2116621C (en) * 1993-03-03 2001-07-24 Rene C. Gaudreault Novel anticancer agents
US5750547A (en) 1995-01-06 1998-05-12 Universite Laval Certain carbanate anti-cancer agents

Also Published As

Publication number Publication date
EP1169303A2 (de) 2002-01-09
ATE312075T1 (de) 2005-12-15
US6686394B1 (en) 2004-02-03
WO2000061546A2 (en) 2000-10-19
WO2000061546A3 (en) 2001-01-11
AU778391B2 (en) 2004-12-02
EP1169303B1 (de) 2005-12-07
DE60028563T2 (de) 2006-11-09
AU3952000A (en) 2000-11-14
BR0010615A (pt) 2003-07-22
MXPA01010311A (es) 2005-09-08
CA2268588A1 (en) 2000-10-12
JP2002541240A (ja) 2002-12-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee