DE60026588D1 - Impfstoffe zur erhöhung der immunantworten gegen herpes simplex virus - Google Patents

Impfstoffe zur erhöhung der immunantworten gegen herpes simplex virus

Info

Publication number
DE60026588D1
DE60026588D1 DE60026588T DE60026588T DE60026588D1 DE 60026588 D1 DE60026588 D1 DE 60026588D1 DE 60026588 T DE60026588 T DE 60026588T DE 60026588 T DE60026588 T DE 60026588T DE 60026588 D1 DE60026588 D1 DE 60026588D1
Authority
DE
Germany
Prior art keywords
type
hsv
nucleic acid
protein
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60026588T
Other languages
English (en)
Other versions
DE60026588T2 (de
Inventor
M Mishkin
J Natuk
W Pride
K Sidhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Wyeth LLC
Original Assignee
Wyeth Holdings LLC
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Holdings LLC, Wyeth LLC filed Critical Wyeth Holdings LLC
Application granted granted Critical
Publication of DE60026588D1 publication Critical patent/DE60026588D1/de
Publication of DE60026588T2 publication Critical patent/DE60026588T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
    • A61K2039/55538—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2000626588 1999-12-17 2000-12-07 Impfstoffe zur erhöhung der immunantworten gegen herpes simplex virus Expired - Fee Related DE60026588T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17231399P 1999-12-17 1999-12-17
US172313P 1999-12-17
PCT/US2000/033105 WO2001044477A1 (en) 1999-12-17 2000-12-07 Method of enhancing immune responses to herpes simplex virus vaccine

Publications (2)

Publication Number Publication Date
DE60026588D1 true DE60026588D1 (de) 2006-05-04
DE60026588T2 DE60026588T2 (de) 2007-01-18

Family

ID=22627181

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2000626588 Expired - Fee Related DE60026588T2 (de) 1999-12-17 2000-12-07 Impfstoffe zur erhöhung der immunantworten gegen herpes simplex virus

Country Status (16)

Country Link
EP (1) EP1238086B1 (de)
JP (1) JP2003517042A (de)
KR (1) KR100773390B1 (de)
CN (1) CN1222619C (de)
AT (1) ATE319833T1 (de)
AU (1) AU783730B2 (de)
BR (1) BR0016419A (de)
CA (1) CA2406678A1 (de)
CY (1) CY1105604T1 (de)
DE (1) DE60026588T2 (de)
DK (1) DK1238086T3 (de)
ES (1) ES2258987T3 (de)
IL (1) IL149810A0 (de)
MX (1) MXPA02005867A (de)
PT (1) PT1238086E (de)
WO (1) WO2001044477A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2504938C (en) * 2002-11-07 2011-10-11 Synergy America, Inc. Compositions and methods for treating or preventing pneumococcal infection
EP3590533A1 (de) 2009-05-22 2020-01-08 Genocea Biosciences, Inc. Impfstoffe gegen den herpes-simplex-virus vom typ 2: zusammensetzungen und verfahren zur auslösung einer immunreaktion
KR101008582B1 (ko) * 2010-09-20 2011-01-17 (주)칠칠공사 달비계용 2중 안전 샤클조립체
EP2643014A4 (de) 2010-11-24 2015-11-11 Genocea Biosciences Inc Impfstoffe gegen den herpes-simplex-virus vom typ 2: zusammensetzungen und verfahren zur auslösung einer immunreaktion
CA2885693C (en) 2011-11-23 2020-07-28 Genocea Biosciences, Inc. Nucleic acid vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
DK2941269T3 (da) 2013-01-07 2021-01-11 Mucosal Vaccine Tech Llc Terapeutiske vacciner til behandling af herpes simplex-virus type 2-infektioner
CA2942166A1 (en) * 2014-03-03 2015-09-11 Albert Einstein College Of Medicine, Inc. Recombinant herpes simplex virus 2 (hsv-2) vaccine vectors
US10918712B2 (en) 2014-03-03 2021-02-16 Albert Einstein College Of Medicine Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors
CN104721839A (zh) * 2015-03-17 2015-06-24 浙江省医学科学院 一种预防单纯疱疹病毒ii型的疫苗
CN104830781A (zh) * 2015-05-05 2015-08-12 杨光华 基于hsv-2抗原的dc细胞、靶向性免疫细胞群及其制备方法和用途
WO2018064232A1 (en) 2016-09-28 2018-04-05 Genocea Biosciences, Inc. Methods and compositions for treating herpes
JP7204653B2 (ja) * 2017-08-30 2023-01-16 Ｋｍバイオロジクス株式会社 改変型ＨＳＶ ｇＤタンパク質及びこれを含むワクチン

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU764036B2 (en) * 1998-02-12 2003-08-07 Wyeth Holdings Corporation Vaccines comprising interleukin-12 and herpes simplex viral antigen

Also Published As

Publication number Publication date
IL149810A0 (en) 2002-11-10
DE60026588T2 (de) 2007-01-18
MXPA02005867A (es) 2002-10-23
JP2003517042A (ja) 2003-05-20
CN1222619C (zh) 2005-10-12
AU2065101A (en) 2001-06-25
WO2001044477A1 (en) 2001-06-21
DK1238086T3 (da) 2006-06-26
EP1238086B1 (de) 2006-03-08
PT1238086E (pt) 2006-07-31
AU783730B2 (en) 2005-12-01
EP1238086A1 (de) 2002-09-11
BR0016419A (pt) 2002-08-20
CY1105604T1 (el) 2010-07-28
CN1434864A (zh) 2003-08-06
ES2258987T3 (es) 2006-09-16
KR20020073348A (ko) 2002-09-23
CA2406678A1 (en) 2001-06-21
KR100773390B1 (ko) 2007-11-09
ATE319833T1 (de) 2006-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee