DE60023547D1 - Partikel zur inhalation - Google Patents

Partikel zur inhalation

Info

Publication number
DE60023547D1
DE60023547D1 DE60023547T DE60023547T DE60023547D1 DE 60023547 D1 DE60023547 D1 DE 60023547D1 DE 60023547 T DE60023547 T DE 60023547T DE 60023547 T DE60023547 T DE 60023547T DE 60023547 D1 DE60023547 D1 DE 60023547D1
Authority
DE
Germany
Prior art keywords
particles
inhalation
droplets
carrier gas
liquid feed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60023547T
Other languages
English (en)
Other versions
DE60023547T3 (de
DE60023547T2 (de
Inventor
Wiwik Watanabe
Petri Ahonen
Esko Kauppinen
Raoul Jaervinen
David Brown
Jorma Jokiniemi
Esa Muttonen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=67253261&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60023547(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Oyj filed Critical Orion Oyj
Publication of DE60023547D1 publication Critical patent/DE60023547D1/de
Application granted granted Critical
Publication of DE60023547T2 publication Critical patent/DE60023547T2/de
Publication of DE60023547T3 publication Critical patent/DE60023547T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
DE60023547.5T 1999-12-30 2000-12-28 PARTIKEL ZUR INHALATION: Herstellungsmethode Expired - Lifetime DE60023547T3 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FI992820 1999-12-30
FI19992820 1999-12-30
FI20002217A FI20002217A (fi) 1999-12-30 2000-10-06 Inhalaatiopartikkelit
FI20002217 2000-10-06
EP00988840.5A EP1242048B2 (de) 1999-12-30 2000-12-28 PARTIKEL ZUR INHALATION: Herstellungsmethode
PCT/FI2000/001151 WO2001049263A1 (en) 1999-12-30 2000-12-28 Inhalation particles

Publications (3)

Publication Number Publication Date
DE60023547D1 true DE60023547D1 (de) 2005-12-01
DE60023547T2 DE60023547T2 (de) 2006-07-27
DE60023547T3 DE60023547T3 (de) 2019-06-13

Family

ID=67253261

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60023547.5T Expired - Lifetime DE60023547T3 (de) 1999-12-30 2000-12-28 PARTIKEL ZUR INHALATION: Herstellungsmethode

Country Status (10)

Country Link
US (1) US20040081626A1 (de)
EP (1) EP1242048B2 (de)
JP (1) JP5139615B2 (de)
AT (1) ATE307570T1 (de)
AU (1) AU2519701A (de)
CA (1) CA2395881C (de)
DE (1) DE60023547T3 (de)
ES (1) ES2251418T5 (de)
FI (1) FI20002217A (de)
WO (1) WO2001049263A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
FI20011386A0 (fi) * 2001-06-28 2001-06-28 Orion Corp Inhalaatiopartikkeleja
JP2005514188A (ja) * 2001-12-07 2005-05-19 エイフェル テクノロジーズ リミテッド 小粒子の合成
US7811606B2 (en) 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
US9808471B2 (en) * 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
US20060009435A1 (en) * 2004-06-23 2006-01-12 Joseph Kaspi Synthesis and powder preparation of fluticasone propionate
GB0425758D0 (en) 2004-11-23 2004-12-22 Vectura Ltd Preparation of pharmaceutical compositions
BR112014025518B1 (pt) 2012-04-13 2022-05-24 Glaxosmithkline Intellectual Property Development Limited Partículas agregadas de umeclidinium, vilanterol e fluticasona, composição em pó, inalador, processo para a preparação de partículas agregadas, e, uso de estearato de magnésio em partículas agregadas
US20140147475A1 (en) 2012-11-29 2014-05-29 Antonius Arnoldus Christiaan Jacobs Vaccine to protect a ruminant against pneumonia caused by pasteurella multocida
EP2976102B1 (de) * 2013-03-18 2019-12-11 Intervet International B.V. Impfstoff zum schutz von wiederkäuern vor lungenentzündung aufgrund von mannheimia haemolytica

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3306250A1 (de) * 1983-02-23 1984-08-23 Basf Ag, 6700 Ludwigshafen Sphaerische einkristalle fuer pharmazeutische zwecke
FR2624505A1 (fr) * 1987-12-11 1989-06-16 Rhone Poulenc Chimie Zircone stabilisee, son procede de preparation et son application dans des compositions ceramiques
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5061682A (en) * 1990-01-17 1991-10-29 The Washington Technology Center Ceramic precursor mixture and technique for converting the same to ceramic
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
US6060069A (en) * 1991-05-20 2000-05-09 Dura Pharmaceuticals, Inc. Pulmonary delivery of pharmaceuticals
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US5819726A (en) * 1993-01-29 1998-10-13 Aradigm Corporation Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease
AU689217B2 (en) * 1994-03-07 1998-03-26 Novartis Ag Methods and compositions for pulmonary delivery of insulin
US6019968A (en) * 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
US5972331A (en) * 1995-12-22 1999-10-26 Schering Corporation Crystalline interferon alpha for pulmonary delivery and method for producing the same
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
ES2236832T3 (es) * 1997-01-16 2005-07-16 Massachusetts Institute Of Technology Preparacion de particulas para inhalacion.
US6051257A (en) * 1997-02-24 2000-04-18 Superior Micropowders, Llc Powder batch of pharmaceutically-active particles and methods for making same
US6165247A (en) * 1997-02-24 2000-12-26 Superior Micropowders, Llc Methods for producing platinum powders
US6338809B1 (en) * 1997-02-24 2002-01-15 Superior Micropowders Llc Aerosol method and apparatus, particulate products, and electronic devices made therefrom
TW453876B (en) * 1999-06-30 2001-09-11 Inhale Therapeutic Syst Spray drying process control of drying kinetics

Also Published As

Publication number Publication date
AU2519701A (en) 2001-07-16
EP1242048B2 (de) 2019-01-23
JP2003519171A (ja) 2003-06-17
EP1242048B1 (de) 2005-10-26
FI20002217A (fi) 2001-07-01
EP1242048A1 (de) 2002-09-25
FI20002217A0 (fi) 2000-10-06
US20040081626A1 (en) 2004-04-29
ES2251418T3 (es) 2006-05-01
JP5139615B2 (ja) 2013-02-06
ATE307570T1 (de) 2005-11-15
DE60023547T3 (de) 2019-06-13
CA2395881A1 (en) 2001-07-12
WO2001049263A1 (en) 2001-07-12
CA2395881C (en) 2009-02-03
ES2251418T5 (es) 2019-07-19
DE60023547T2 (de) 2006-07-27

Similar Documents

Publication Publication Date Title
FI20010115A0 (fi) Menetelmä nanopartikkelien valmistamiseksi
ATE307570T1 (de) Partikel zur inhalation
AU616992B2 (en) Solid aerosol generator
Jayasinghe et al. Controlled deposition of nanoparticle clusters by electrohydrodynamic atomization
CA2280865A1 (en) Aerosol method and apparatus, particulate products, and electronic devices made therefrom
DE69508770T2 (de) Suspension plasmabeschichtung
JPS5676235A (en) Granulator
TW200706615A (en) Powder coating materials
DE60107862D1 (de) Inhalationspartikel bestehend aus mindestens zwei wirkstoffen
EP0361396B1 (de) Verfahren und Vorrichtung zum Herstellen eines Pulvers von amorphen Partikeln einer keramischen oder metallischen Substanz
FI895015A0 (fi) Foerfarande och apparatur foer framstaellning av baerare foer polymerisationskatalysatorer.
US5173274A (en) Flash liquid aerosol production method and appartus
FI20002216A0 (fi) Yhdistelmäpartikkelit astman hoitoon
CN1551797B (zh) 流化床造粒方法
US11794126B2 (en) System, apparatuses, devices, and methods for producing particles
CA2230539A1 (en) Apparatus and process for coating a solid particle
ATE333948T1 (de) Gas kollimator für eine kinetische pulversprühdüse
CN100434152C (zh) 制备尿素颗粒的方法
Strauss et al. Effect of gas propreties on powder yield produced by close-coupled gas atomization
Jayasinghe et al. Electrostatic atomization of chitosan.
DE60220536D1 (de) Vorrichtung zur erzeugung von tröpfchenstrahlen eines mit teilchen gefüllten viskosen mediums
TWI302112B (de)
Jaworek et al. Generation of Charged Aerosol by Electrodynamic Method
RU2134965C1 (ru) Способ получения гранулированного хлорофоса
Leifsen Spot Paint Sprayer