DE60017787D1 - Strahlung-sensitive liposomen - Google Patents

Strahlung-sensitive liposomen

Info

Publication number
DE60017787D1
DE60017787D1 DE60017787T DE60017787T DE60017787D1 DE 60017787 D1 DE60017787 D1 DE 60017787D1 DE 60017787 T DE60017787 T DE 60017787T DE 60017787 T DE60017787 T DE 60017787T DE 60017787 D1 DE60017787 D1 DE 60017787D1
Authority
DE
Germany
Prior art keywords
liposome
radiation
liposomal
present
sensitive liposomes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60017787T
Other languages
English (en)
Other versions
DE60017787T2 (de
Inventor
F O'brien
A Mcgovern
Bruce Bondurant
M Sutherland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Arizona
Original Assignee
University of Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Arizona filed Critical University of Arizona
Application granted granted Critical
Publication of DE60017787D1 publication Critical patent/DE60017787D1/de
Publication of DE60017787T2 publication Critical patent/DE60017787T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Radiation-Therapy Devices (AREA)
DE60017787T 1999-11-30 2000-11-30 Strahlung-sensitive liposomen Expired - Lifetime DE60017787T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16810099P 1999-11-30 1999-11-30
US168100P 1999-11-30
PCT/US2000/032902 WO2001039744A2 (en) 1999-11-30 2000-11-30 Radiation sensitive liposomes

Publications (2)

Publication Number Publication Date
DE60017787D1 true DE60017787D1 (de) 2005-03-03
DE60017787T2 DE60017787T2 (de) 2006-01-05

Family

ID=22610124

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60017787T Expired - Lifetime DE60017787T2 (de) 1999-11-30 2000-11-30 Strahlung-sensitive liposomen

Country Status (7)

Country Link
US (4) US6989153B2 (de)
EP (1) EP1233752B1 (de)
JP (2) JP4829454B2 (de)
AT (1) ATE287700T1 (de)
AU (1) AU2427601A (de)
DE (1) DE60017787T2 (de)
WO (1) WO2001039744A2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989153B2 (en) 1999-11-30 2006-01-24 Varian Medical Systems Technologies, Inc. Radiation sensitive liposomes
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US6838452B2 (en) 2000-11-24 2005-01-04 Vascular Biogenics Ltd. Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
US20060014013A1 (en) * 2001-03-10 2006-01-19 Saavedra Steven S Stabilized biocompatible supported lipid membrane
CA2449054C (en) * 2001-05-30 2011-01-04 The Scripps Research Institute Integrin targeting liposome for nucleic acid delivery
EP1436313B1 (de) 2001-10-19 2010-09-22 Vascular Biogenics Ltd. Polynukleotidkonstrukte, pharmazeutische zusammensetzungen und verfahren zur gezielten herunterregulierung von angiogenese und zur krebstherapie
AR036316A1 (es) * 2002-08-29 2004-08-25 Monte Verde S A Una composicion farmaceutica de liposomas de tamano pequeno y metodo de preparacion
FR2848854B1 (fr) * 2002-12-24 2005-03-18 Coletica Particules comprenant un biopolymere degradable sous l'effet d'une onde electromagnetique telle qu'emise par un rayonnement solaire
US7711313B2 (en) * 2004-05-14 2010-05-04 Google Inc. Broadcast monitoring system and method for intelligent optimization
EP1600153A1 (de) * 2004-05-26 2005-11-30 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Wirkstoffabgabe-Überwachung ermöglichende pharmazeutische Zusammensetzung mit verzögerter Freisetzung
US7807847B2 (en) 2004-07-09 2010-10-05 Vascular Biogenics Ltd. Process for the preparation of oxidized phospholipids
EP2058009A4 (de) * 2006-08-31 2009-10-28 Astellas Pharma Inc Reverse-targeting-lipidvesikel
US8569529B2 (en) 2007-01-09 2013-10-29 Vascular Biogenics Ltd. High-purity phospholipids
US9006217B2 (en) 2007-01-09 2015-04-14 Vascular Biogenics Ltd. High-purity phospholipids
US20100104628A1 (en) * 2007-03-28 2010-04-29 Duke University method of treating neuroblastoma
US8784846B2 (en) * 2007-07-30 2014-07-22 Loma Linda University Medical Center Systems and methods for particle radiation enhanced delivery of therapy
JP5370153B2 (ja) * 2007-08-20 2013-12-18 コニカミノルタ株式会社 造影剤用化合物含有糖修飾リポソーム及び造影剤
WO2009042839A1 (en) * 2007-09-28 2009-04-02 Varian Medical Systems, Inc. Radiation sensitive liposomes
JP5207169B2 (ja) * 2007-10-18 2013-06-12 独立行政法人日本原子力研究開発機構 電離放射線分解性リポソーム、それを用いたリポソーム製剤、並びにリポソームの調整方法
JP5752599B2 (ja) 2008-11-06 2015-07-22 ヴァスキュラー バイオジェニックス リミテッド 酸化脂質化合物およびその使用
WO2010114901A1 (en) 2009-03-31 2010-10-07 The Board Of Trustees Of The University Of Arkansas Method of controlled drug release from a liposome carrier
AR076284A1 (es) 2009-04-29 2011-06-01 Bayer Schering Pharma Ag Inmunoconjugados de antimesotelina y usos de los mismos
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
KR102035187B1 (ko) * 2011-04-06 2019-11-08 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 지질-기반 나노입자들
US9849087B2 (en) 2011-11-08 2017-12-26 The Board Of Trustees Of The University Of Arkansas Methods and compositions for X-ray induced release from pH sensitive liposomes
MX366972B (es) 2012-01-20 2019-08-01 Ananth Annapragada Metodos y composiciones para caracterizar imagenes medicas en forma objetiva.
US9993553B2 (en) 2013-03-14 2018-06-12 The Regents Of The University Of California Methods and compositions for targeted release of molecules from nanoscale carriers
WO2016016790A1 (en) * 2014-07-31 2016-02-04 Universita' Degli Studi Di Cagliari Ester of a phospholipid with conjugated linoleic acid for the treatment of psychiatric disorders with neuroinflammatory and neurodegenerative basis
EP3542828A1 (de) 2014-10-08 2019-09-25 Texas Children's Hospital Mrt-bildgebung von amyloider plaque mittels liposomen
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
WO2016084023A1 (en) 2014-11-26 2016-06-02 Vascular Biogenics Ltd. Oxidized lipids and treatment or prevention of fibrosis
US10842746B1 (en) 2016-08-25 2020-11-24 Verily Life Sciences Llc Bi-directionally crosslinked liposomes and method of making same
TW202039026A (zh) 2019-03-08 2020-11-01 美商美威高能離子醫療系統公司 藉由管柱之輻射遞送及自其產生治療計劃
WO2022092411A1 (ko) * 2020-10-30 2022-05-05 가천대학교 산학협력단 대식작용 추적 pet 이미징을 위한 리포좀 및 이를 포함하는 나노 프로브
EP4356930A1 (de) 2022-10-21 2024-04-24 Universite De Bordeaux Lichtempfindliche diazirinkonjugierte phospholipide und deren verwendungen

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061484A (en) * 1988-03-11 1991-10-29 Alpha Therapeutic Corporation Perfluorochemical emulsion with stabilized vesicles
US20020150539A1 (en) * 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5088499A (en) 1989-12-22 1992-02-18 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
FR2694559B1 (fr) * 1992-08-06 1994-10-28 Atta Nouveaux dérivés amphiphiles d'aminoacides ou de peptides, leur procédé de préparation et leur utilisation dans des préparations à usage biomédical.
US5366881A (en) * 1993-02-23 1994-11-22 The United States Of America As Represented By The Secretary Of The Navy Polymerizable lipids for preparing vesicles that controllably release an encapsulant
US6531156B1 (en) * 1994-04-15 2003-03-11 Temple University Aqueous solven encapsulation method, apparatus and microcapsules
US20020010144A1 (en) * 1994-04-29 2002-01-24 Robert Sobol Enhancing the sensitivity of tumor cells to therapies
US6080423A (en) * 1994-08-11 2000-06-27 Regents Of The University Of California Three dimensional colorimetric assay assemblies
US5885613A (en) 1994-09-30 1999-03-23 The University Of British Columbia Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
US6090800A (en) * 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US6159443A (en) * 1999-04-29 2000-12-12 Vanderbilt University X-ray guided drug delivery
US6989153B2 (en) 1999-11-30 2006-01-24 Varian Medical Systems Technologies, Inc. Radiation sensitive liposomes
GB0518890D0 (en) * 2005-09-15 2005-10-26 Ucl Biomedica Plc Method of determining damage to skin
US20080314767A1 (en) * 2007-06-22 2008-12-25 Bausch & Lomb Incorporated Ophthalmic Solutions

Also Published As

Publication number Publication date
WO2001039744A2 (en) 2001-06-07
WO2001039744A3 (en) 2002-01-24
US20020064554A1 (en) 2002-05-30
DE60017787T2 (de) 2006-01-05
ATE287700T1 (de) 2005-02-15
EP1233752A2 (de) 2002-08-28
JP2011173896A (ja) 2011-09-08
US20110217236A1 (en) 2011-09-08
JP2003515550A (ja) 2003-05-07
JP4829454B2 (ja) 2011-12-07
US20130053618A1 (en) 2013-02-28
US8535712B2 (en) 2013-09-17
EP1233752B1 (de) 2005-01-26
US20060099141A1 (en) 2006-05-11
US6989153B2 (en) 2006-01-24
AU2427601A (en) 2001-06-12

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