DE60006698D1 - Unsubstituierte ethyl- und propylderivate von phenoxythienoisoxazolen als d4 antagonisten - Google Patents

Unsubstituierte ethyl- und propylderivate von phenoxythienoisoxazolen als d4 antagonisten

Info

Publication number
DE60006698D1
DE60006698D1 DE60006698T DE60006698T DE60006698D1 DE 60006698 D1 DE60006698 D1 DE 60006698D1 DE 60006698 T DE60006698 T DE 60006698T DE 60006698 T DE60006698 T DE 60006698T DE 60006698 D1 DE60006698 D1 DE 60006698D1
Authority
DE
Germany
Prior art keywords
phenoxythienoisoxazoles
antagonists
unsubstituted ethyl
propyl derivatives
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60006698T
Other languages
English (en)
Other versions
DE60006698T2 (de
Inventor
E Lee
A Ayers
G Jurcak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Application granted granted Critical
Publication of DE60006698D1 publication Critical patent/DE60006698D1/de
Publication of DE60006698T2 publication Critical patent/DE60006698T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
DE60006698T 1999-09-14 2000-09-13 Unsubstituierte ethyl- und propylderivate von phenoxythienoisoxazolen als d4 antagonisten Expired - Lifetime DE60006698T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39615699A 1999-09-14 1999-09-14
US396156 1999-09-14
PCT/US2000/024949 WO2001019832A2 (en) 1999-09-14 2000-09-13 Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists

Publications (2)

Publication Number Publication Date
DE60006698D1 true DE60006698D1 (de) 2003-12-24
DE60006698T2 DE60006698T2 (de) 2004-09-23

Family

ID=23566087

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60006698T Expired - Lifetime DE60006698T2 (de) 1999-09-14 2000-09-13 Unsubstituierte ethyl- und propylderivate von phenoxythienoisoxazolen als d4 antagonisten

Country Status (23)

Country Link
EP (1) EP1216249B1 (de)
JP (1) JP4717306B2 (de)
KR (1) KR20020027644A (de)
AR (1) AR032135A1 (de)
AT (1) ATE254620T1 (de)
AU (1) AU7577200A (de)
BR (1) BR0014513A (de)
CA (1) CA2383327C (de)
CZ (1) CZ2002896A3 (de)
DE (1) DE60006698T2 (de)
DK (1) DK1216249T3 (de)
EA (1) EA004177B1 (de)
EE (1) EE200200133A (de)
ES (1) ES2206305T3 (de)
HU (1) HUP0202712A3 (de)
IL (1) IL148522A0 (de)
MX (1) MXPA02002690A (de)
NO (1) NO20021249L (de)
PL (1) PL354481A1 (de)
PT (1) PT1216249E (de)
SK (1) SK3502002A3 (de)
WO (1) WO2001019832A2 (de)
ZA (1) ZA200201760B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0207449D0 (en) * 2002-03-28 2002-05-08 Glaxo Group Ltd Novel compounds
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728651A (en) * 1985-10-24 1988-03-01 Hoechst-Roussel Pharmaceuticals Inc. Antihypertensive thieno-isoxazoles and -pyrazoles
US6187774B1 (en) * 1996-03-04 2001-02-13 Yoshitomi Pharmaceutical Industries, Ltd. Fused heterocyclic compounds and pharmaceutical applications thereof
HUP9603001A3 (en) * 1996-10-30 1999-07-28 Richter Gedeon Vegyeszet Heterocycle compounds comprising nitrogen, process for producing them and pharmaceutical compositions containing the same
JP4627882B2 (ja) * 1998-02-09 2011-02-09 デユフアー・インターナシヨナル・リサーチ・ベー・ブイ Ｄ４−アンタゴニスト活性を有するベンズイソキサゾール誘導体

Also Published As

Publication number Publication date
EA004177B1 (ru) 2004-02-26
CA2383327A1 (en) 2001-03-22
WO2001019832A3 (en) 2001-10-04
EP1216249B1 (de) 2003-11-19
ATE254620T1 (de) 2003-12-15
AR032135A1 (es) 2003-10-29
JP4717306B2 (ja) 2011-07-06
KR20020027644A (ko) 2002-04-13
IL148522A0 (en) 2002-09-12
HUP0202712A2 (hu) 2002-12-28
CZ2002896A3 (cs) 2002-08-14
EA200200357A1 (ru) 2002-10-31
EE200200133A (et) 2003-04-15
ES2206305T3 (es) 2004-05-16
NO20021249D0 (no) 2002-03-13
PL354481A1 (en) 2004-01-26
JP2003509431A (ja) 2003-03-11
MXPA02002690A (es) 2004-09-10
BR0014513A (pt) 2002-07-02
SK3502002A3 (en) 2002-09-10
ZA200201760B (en) 2003-08-27
EP1216249A2 (de) 2002-06-26
DE60006698T2 (de) 2004-09-23
PT1216249E (pt) 2004-04-30
AU7577200A (en) 2001-04-17
CA2383327C (en) 2009-11-03
DK1216249T3 (da) 2004-03-15
NO20021249L (no) 2002-05-10
HUP0202712A3 (en) 2004-12-28
WO2001019832A2 (en) 2001-03-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS HOLDINGS INC., GREENVILLE, DEL., US

8327 Change in the person/name/address of the patent owner

Owner name: AVENTISUB II INC., GREENVILLE, DEL., US